2-AMINO-5-CHLOROBENZOPHENONE OXIME
Description Reference- Product Name
- 2-AMINO-5-CHLOROBENZOPHENONE OXIME
- CAS No.
- 18097-52-4
- Chemical Name
- 2-AMINO-5-CHLOROBENZOPHENONE OXIME
- Synonyms
- AKOS 90376;TIMTEC-BB SBB003174;Oxazepam Impurity 3;Mixtureofsyn-andanti-isomeres;2-Amino-5-Chlor-Benzophenonoxim;2-Amino-5-Chlorobenzopheone Oxime;2-AMINO-5-CHLOROBENZOPHENONE OXIME;2-AMINO-5-CHLOROBENZOPHENEONE OXIME;2-Amino-5-chlorobenzophenoneα-oxime-,(Z)-;(2-amino-5-chlorophenyl)phenyl-methanonoxime
- CBNumber
- CB4368100
- Molecular Formula
- C13H11ClN2O
- Formula Weight
- 246.69
- MOL File
- 18097-52-4.mol
2-AMINO-5-CHLOROBENZOPHENONE OXIME Property
- Melting point:
- 117-120oC
- Boiling point:
- 434.9±45.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- pka
- 10.20±0.28(Predicted)
- color
- Pale Yellow to Light Yellow
- EPA Substance Registry System
- Methanone, (2-amino-5-chlorophenyl)phenyl-, oxime (18097-52-4)
Safety
- Safety Statements
- 24/25
- HS Code
- 29280090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- S413445
- Product name
- 2-AMINO-5-CHLOROBENZOPHENONE OXIME (MIXTURE OF SYN AND ANTI ISOMERS)
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $179
- Updated
- 2024/03/01
- Product number
- A603730
- Product name
- 2-Amino-5-chlorobenzophenoneOxime(E/Zmixture)
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A603730
- Product name
- 2-Amino-5-chlorobenzophenoneOxime(E/Zmixture)
- Packaging
- 5G
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 002114
- Product name
- 2-Amino-5-chlorobenzophenone Oxime
- Packaging
- 250mg
- Price
- $312
- Updated
- 2021/12/16
- Product number
- FA67520
- Product name
- 2-Amino-5-chlorobenzophenone oxime
- Packaging
- 5G
- Price
- $100
- Updated
- 2021/12/16
2-AMINO-5-CHLOROBENZOPHENONE OXIME Chemical Properties,Usage,Production
Description
2-Amino-5-Chlorobenzophenone is in the form of a yellow-brown crystalline powder. Its melting point is 98-100°C. It is used to produce intermediates for the synthesis of Oxazolam drug and intermediates for psychotherapeutic agents, such as chlorodiazepoxide and diazepam.1,2
Reference
- R. Liao, Synthetic method of Oxazolam drug intermediate 2-amino-5-chlorobenzophenone, Patent CN105461576A
- S. Nakanishi, W. E. Barth, Process for preparing 6-chloromethyl-4-phenylquinazoline-3-oxide and intermediates therefor, Patent US3932325A
Chemical Properties
yellow crystalline powder
Uses
Intermediate in the preparation of Chlordiazepoxide (C327050) and its metabolites.
Definition
ChEBI: (2-amino-5-chlorophenyl)(phenyl)methanone oxime is a diarylmethane.
Synthesis Reference(s)
The Journal of Organic Chemistry, 30, p. 3957, 1965 DOI: 10.1021/jo01022a519
2-AMINO-5-CHLOROBENZOPHENONE OXIME Preparation Products And Raw materials
Raw materials
Preparation Products
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