ChemicalBook > CAS DataBase List > H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH
H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH
- Product Name
- H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH
- CAS No.
- 79994-24-4
- Chemical Name
- H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH
- Synonyms
- YGGFLRRIRP;DYNORPHIN A (1-10);Porcine dynorphin A(1-10);DYNORPHIN A (1-10), PORCINE;dynorphin A, porcine, fragment 1-10;TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO;dynorphin A fragment 1-10 porcine*sequence;H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH;DYNORPHIN A (1-10) SYNTHETIC >97% OPIOID AGONIST
- CBNumber
- CB4395153
- Molecular Formula
- C57H91N19O12
- Formula Weight
- 1234.45
- MOL File
- 79994-24-4.mol
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H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH Property
- storage temp.
- -15°C
- solubility
- Soluble in DMSO
- Sequence
- Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro
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N-Bromosuccinimide Price
Biorbyt Ltd
- Product number
- orb364565
- Product name
- Dynorphin A (1-10)
- Purity
- > 95%
- Packaging
- 1mg
- Price
- $287.3
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb364565
- Product name
- Dynorphin A (1-10)
- Purity
- > 95%
- Packaging
- 5mg
- Price
- $552.5
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0001226
- Product name
- DYNORPHIN A (1 - 10), PORCINE
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $594.25
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb364565
- Product name
- Dynorphin A (1-10)
- Purity
- > 95%
- Packaging
- 10mg
- Price
- $708.9
- Updated
- 2021/12/16
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H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH Chemical Properties,Usage,Production
Uses
Dynorphin A (1-10) an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) also blocks NMDA-activated current with an IC50 of 42.0 μM.
IC 50
NMDA Receptor; κ Opioid Receptor/KOR
References
[1] Paterlini G, et al. Molecular simulation of dynorphin A-(1-10) binding to extracellular loop 2 of the kappa-opioidreceptor. A model for receptor activation. J Med Chem. 1997 Sep 26;40(20):3254-62. DOI:10.1021/jm970252j
[2] Chen L, et al. Dynorphin block of N-methyl-D-aspartate channels increases with the peptide length. J Pharmacol Exp Ther. 1998 Mar;284(3):826-31. PMID:9495839
H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH Suppliers
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79994-24-4, H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OHRelated Search:
RIMORPHIN
TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2
Dynorphin A (1-13)
DYNORPHIN B (1-9)
dynorphin B (1-29)
LEU-ENKEPHALIN-ARG
H-ALA-ALA-PRO-OH
DES-TYR1-LEUCINE ENKEPHALINAMIDE ACETATE SALT
H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH
LEU-ENKEPHALIN AMIDE
H-VAL-GLY-GLY-OH