TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2

Product Name: TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2
CAS No.: 80448-90-4
Chemical Name: TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2
Synonyms: DYNORPHIN A;dynorphin-(1-17);Dynorphin A【pig】;Dynorphin A【rat】;Dynorphin A admin;YGGFLRRIRPKLKWDNQ;DYNORPHIN A AMIDE;Dynorphin acetate;DYNORPHIN A (1-17);DYNORPHIN A(HUMAN)
CBNumber: CB7135123
Molecular Formula: C99H155N31O23
Formula Weight: 2147.52
MOL File: 80448-90-4.mol

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TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 Property

Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Methanol (Slightly), Water (Slightly)
form: Solid
color: White to off-white
Water Solubility: Soluble to 0.80 mg/ml in water
Sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-21

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D8147
Product name: Dynorphin A porcine
Purity: ≥95% (HPLC)
Packaging: 0.1mg
Price: $111
Updated: 2025/07/31

Sigma-Aldrich

Product number: D8147
Product name: Dynorphin A porcine
Purity: ≥95% (HPLC)
Packaging: 0.5mg
Price: $339
Updated: 2025/07/31

Cayman Chemical

Product number: 18169
Product name: Dynorphin A
Purity: ≥95%
Packaging: 500μg
Price: $37
Updated: 2021/12/16

Cayman Chemical

Product number: 18169
Product name: Dynorphin A
Purity: ≥95%
Packaging: 1mg
Price: $70
Updated: 2021/12/16

Sigma-Aldrich

Product number: D8147
Product name: Dynorphin A porcine
Purity: ≥95% (HPLC)
Packaging: 1mg
Price: $424.2
Updated: 2025/07/31

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TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 Chemical Properties,Usage,Production

Uses

Dynorphin A has been used in immunohistochemistry.

Biochem/physiol Actions

Dynorphin A porcine is an opioid peptide. It is an endogenous κ-agonist that is resistant to enzymatic degradation. Dynorphin A has the ability to decrease calcium current by selectively decreasing the large inactivating (N) calcium current. It can decrease the calcium-dependent action potential duration of DRG (dorsal root ganglion) and myenteric neurons.

in vivo

Dynorphin A (intracerebroventricular injection, 1 μg of 2 μL, a single dose) inhibits vasopressin (VP) release in 24 h water-deprived male rats^[5].
Dynorphin A (intracerebroventricular injection, 500 pmol/5 μL per day for 4 d) alleviates stress-induced behavioral impairments in ddY mice accompanied by regulation of the 5-HTergic system in the brain^[6].

Animal Model:	24 h water-deprived male rats^[5]
Dosage:	1 μg of 2 μL
Administration:	Intracerebroventricular injection
Result:	Inhibited vasopressin (VP) release 30 min upon injection.

Animal Model:	Male ddY mice^[6]
Dosage:	15, 150, 1500 pmol/5 μL per day for 4 days
Administration:	Intracerebroventricular injection
Result:	Attenuated the repeated stress-induced escape failures from the shock.

IC 50

Human Endogenous Metabolite; Caspase 3; κ Opioid Receptor/KOR

storage

Store at -20°C

TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 Suppliers

China 110 Europe 1 France 1 Germany 3 Japan 2 Switzerland 1 United Kingdom 1 United States 14 Global 133

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80448-90-4, TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2Related Search:

LEU-ENKEPHALIN-ARG H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH dynorphin B (1-29) DYNORPHIN B (1-9) Dynorphin A (1-13) RIMORPHIN Aceglutamide GLYCYL-L-GLUTAMINE MONOHYDRATE TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 AC-TRP-NH2 L-Alanyl-L-Glutamine Glycyl-L-glutamine monohydrate LEU-ENKEPHALIN AMIDE DYNORPHIN A (1-11) AMIDE DYNORPHIN A (1-10) AMIDE H-TRP-BETA-ALA-OH AC-TRP-NHME L-TRP-GLY AMIDE

YGGFLRRIRPKLKWDNQ

TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN

TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2

TRY-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN

PRODYNORPHIN (207-223) (HUMAN)

PRODYNORPHIN (209-225)

Dynorphin A admin

DYNORPHIN A

DYNORPHIN A (1-17)

DYNORPHIN A (HUMAN) (PORCINE, RAT, BOVINE)

DYNORPHIN A PORCINE

DYNORPHIN A AMIDE

DYNORPHIN A AMIDE, PORCINE

DYNORPHIN A(HUMAN)

DYNORPHIN A PRODYNORPHIN (207-223), HUMAN

H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-OH

PRODYNORPHIN (209-225) (PORCINE)

dynorphin-(1-17)

Dynorphin A【pig】

Dynorphin A【rat】

L-Tyr-Gly-Gly-L-Phe-L-Leu-L-Arg-L-Arg-L-Ile-L-Arg-L-Pro-L-Lys-L-Leu-L-Lys-L-Trp-L-Asp-L-Asn-L-Gln-OH

Dynorphin A (1-17), (Prodynorphin 209-225), Porcine

Dynorphin A (swine)

Dynorphin A (human, porcine)

Dynorphin acetate

Prodynorphin (207-223) (huMan), Prodynorphin (209-225) (porcine)

Dynorphins(1 - 17)

Dynorphin (1-17), Dynorphin (1-13)

Dynorphin A amide, porcine YGGFLRRIRPKLKWDNQ-NH2

TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 USP/EP/BP

Dynorphin A, kappa agonist

Dynorphin A (1-17) Peptide Fragment

Dynorphin A (Dynorphin A (1-17))

Dynorphin A (1-17) (Porcine)

Dynorphin A porcine/80448-90-4/95%

80448-90-4

C99H155N31O23

BioChemical

Biochemicals and Reagents

Amino Acids and Peptides

Dynorphins

Opioid Peptides

Peptides

Opioid receptor and opioid-like receptor

peptide