LEU-ENKEPHALIN AMIDE

Product Name: LEU-ENKEPHALIN AMIDE
CAS No.: 60117-24-0
Chemical Name: LEU-ENKEPHALIN AMIDE
Synonyms: YGGFL-NH2;NSC 351912;LEU-ENKEPHALIN NH2;enkephalinamide-leu;LEU-ENKEPHALIN AMIDE;[LEU5]-ENKEPHALIN AMIDE;DYNORPHIN A (1-5) AMIDE;TYR-GLY-GLY-PHE-LEU-NH2;leucine enkephalinamide;H-TYR-GLY-GLY-PHE-LEU-NH2
CBNumber: CB8373676
Molecular Formula: C28H38N6O6
Formula Weight: 554.64
MOL File: 60117-24-0.mol

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LEU-ENKEPHALIN AMIDE Property

Melting point:: 123-126 °C
Boiling point:: 1012.8±65.0 °C(Predicted)
Density: 1.254±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: Soluble in DMSO
pka: 9.97±0.15(Predicted)
form: Solid
color: White to off-white
Sequence: Tyr-Gly-Gly-Phe-Leu-NH2

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0044406
Product name: [Leu5]-Enkephalin,amide
Purity: 99.44%
Packaging: 10mg
Price: $70
Updated: 2021/12/16

ChemScene

Product number: CS-0044406
Product name: [Leu5]-Enkephalin,amide
Purity: 99.44%
Packaging: 25mg
Price: $110
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0000183
Product name: [LEU5]-ENKEPHALIN, AMIDE
Purity: 95.00%
Packaging: 1MG
Price: $405.55
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0000183
Product name: [LEU5]-ENKEPHALIN, AMIDE
Purity: 95.00%
Packaging: 5MG
Price: $427.2
Updated: 2021/12/16

1Pluschem

Product number: 1P00EACW
Product name: LEU-ENKEPHALIN AMIDE
Purity: 99%
Packaging: 25mg
Price: $145
Updated: 2021/12/16

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LEU-ENKEPHALIN AMIDE Chemical Properties,Usage,Production

Uses

[Leu5]-Enkephalin, amide is a δ opioid receptor agonist.

in vivo

Levels of [Leu5]-Enkephalin are significantly increased in the nucleus raphe magnus (NRM) of rats 2 weeks after the injection of complete Freund's adjuvant (CFA) (1.02±0.2 pmol/mg protein) as compared with saline-treated rats (0.49±0.04 pmol/mg protein; p<0.01). Tissue levels of [Leu5]-Enkephalin are uniformly increased in the caudal ventrolateral periaqueductal gray (PAG) 4 hr (1.15±0.25 pmol/mg protein), 4 d (1.16±0.18 pmol/mg protein), and 2 weeks (1.18±0.17 pmol/mg protein) after the injection of CFA as compared with saline-treated rats (0.55±0.03 pmol/mg protein; p<0.05, all times). A smaller increase in the levels of [Leu5]-Enkephalin occurred in the rostral aspect of the ventrolateral PAG at all time points. Finally, levels of [Leu5]-Enkephalin are also increased in the contralateral microcellular tegmental nucleus 4 d after the injection of CFA (0.53±0.04 pmol/mg protein) compared with levels in saline-treated rats (0.38±0.02 pmol/mg protein; p<0.05)^[1].

References

[1] Hurley RW, et al. Contribution of endogenous enkephalins to the enhanced analgesic effects of supraspinal mu opioid receptor agonists after inflammatory injury. J Neurosci. 2001 Apr 1;21(7):2536-45. DOI:10.1523/JNEUROSCI.21-07-02536.2001
[2] Kennedy C, et al. [Met5]enkephalin acts via delta-opioid receptors to inhibit pelvic nerve-evoked contractions of cat distal colon. Br J Pharmacol. 1987 Oct;92(2):291-8. DOI:10.1111/j.1476-5381.1987.tb11323.x

LEU-ENKEPHALIN AMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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LEU-ENKEPHALIN AMIDE Suppliers

China 58 Germany 2 Switzerland 1 The Netherlands 1 United Kingdom 1 United States 12 Global 75

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29760
Advantage: 68

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4802
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

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View Lastest Price from LEU-ENKEPHALIN AMIDE manufacturers

Career Henan Chemical Co

Product: LEU-ENKEPHALIN AMIDE 60117-24-0
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-18

60117-24-0, LEU-ENKEPHALIN AMIDERelated Search:

CYT-1010 MM 54 H-ALA-ARG-LEU-ASP-VAL-ALA-SER-GLU-PHE-ARG-LYS-LYS-TRP-ASN-LYS-TRP-ALA-LEU-SER-ARG-NH2 PACAP (1-27), human, ovine, rat (TFA) BAY 55-9837 H-ALA-VAL-SER-GLU-HIS-GLN-LEU-LEU-HIS-ASP-LYS-GLY-LYS-SER-ILE-GLN-ASP-LEU-ARG-ARG-ARG-PHE-PHE-LEU-HIS-HIS-LEU-ILE-ALA-GLU-ILE-HIS-THR-ALA-OH Met-enkephalinamide Dynorphin A (1-13) TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 H-TYR-GLY-GLY-PHE-LEU-D-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-OH LEU-ENKEPHALIN-ARG-PHE LEU-ENKEPHALIN-ARG H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-OH DYNORPHIN B TYR-GLY-GLY-PHE-LEU-ARG-LYS-ARG DYNORPHIN A (1-10) AMIDE H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-D-ARG-ARG-PRO-LYS-LEU-LYS-OH H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-OH

ALPHA-NEOENDORPHIN (1-5) AMIDE

leucine enkephalinamide acetate

DYNORPHIN A (1-5) AMIDE

DYNORPHIN A (1-5) AMIDE ACETATE SALT

H-TYR-GLY-GLY-PHE-LEU-NH2

H-TYR-GLY-GLY-PHE-LEU-NH2 ACETATE SALT

LEU-ENKEPHALIN NH2

LEU-ENKEPHALIN AMIDE

[LEU5]-ENKEPHALIN AMIDE

enkephalinamide-leu

YGGFL-NH2

TYR-GLY-GLY-PHE-LEU-NH2

leucine enkephalinamide

4-Hydroxy-L-Phe-Gly-Gly-Phe-Leu-NH2

L-Tyr-Gly-Gly-L-Phe-L-Leu-NH2

a-Neoendorphin (1-5) aMide, Dynorphin A (1-5) aMide

Leu-Enkephalin amide,α-Neoendorphin (1-5) amide

Leu-Enkephalin amide acetate salt

L-Leucinamide, L-tyrosylglycylglycyl-L-phenylalanyl-

NSC 351912

Leu-Enkephalin amide acetate salt H-Tyr-Gly-Gly-Phe-Leu-NH2 acetate salt

60117-24-0

C28H38N6O6

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical

Enkephalins

Peptides

Opioid Peptides