ChemicalBook > CAS DataBase List > tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu

tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu

Product Name
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
CAS No.
1118767-16-0
Chemical Name
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
Synonyms
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu;Semaglutide side chain;(S)-22-(tert-butoxycarbonyl)-43,43-dimethyl-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontanoic acid;Side chain;Semaglutide linker;Carbaryl Impurity 3;Egf(a) analogue-13C4;Somaluptide side chain;Semaglutide impurity 22;tBuO-Ste-Glu(AEEA-AEEA)-OtBu
CBNumber
CB43975343
Molecular Formula
C43H79N3O13
Formula Weight
846.1
MOL File
1118767-16-0.mol
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tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu Property

Boiling point:
940.6±65.0 °C(Predicted)
Density 
1.079±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place, Sealed in dry, Store in freezer, under -20°C
pka
3.39±0.10(Predicted)
InChIKey
YZUXNRZPWYRMGH-DHUJRADRSA-N
SMILES
C(O)(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(OC(C)(C)C)=O)NC(=O)CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemPep
Product number
181927
Product name
Octa(OtBu)-Glu(AEEA-AEEA-OH)-OtBu
Packaging
1g
Price
$800
Updated
2021/12/16
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tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu Chemical Properties,Usage,Production

Description

tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu is the 18-carbon fatty acid side chain of somatostatin, which contributes to an increased affinity for albumin (approximately 5-6 fold). Somalutide is a glucagon-like peptide-1 (GLP-1) analogue with hypoglycaemic properties.

Uses

(S)-22-(Tert-butoxycarbonyl)-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontane-1,41-dioic acid can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and chemical production processes.

Definition

TBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu is also known as Semaglutide Side Chain. An 18-carbon fatty acid side chain of semaglutide. The affinity of the semaglutide side chain for albumin was enhanced 5-6 times. Semaglutide is a glucagon-like peptide-1 (GLP-1) analog with significant hypoglycemic efficacy.

Application

OLED intermediates, Pharmaceutical Raw Intermediates, Fine Chemical Intermediate

tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu Suppliers

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View Lastest Price from tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
(S)-22-(tert-butoxycarbonyl)-43,43-dimethyl-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontanoic acid 1118767-16-0
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98
Supply Ability
1
Release date
2021-07-06
Henan Fengda Chemical Co., Ltd
Product
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu 1118767-16-0
Price
US $2.00-0.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-15
Alpha Biopharmaceuticals Co., Ltd
Product
Octadecane(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH 1118767-16-0
Price
US $0.00-0.00/g
Min. Order
1g
Purity
>98%
Supply Ability
15kg per batch
Release date
2024-01-26

1118767-16-0, tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBuRelated Search:

Semaglutide intermediate Semaglutide Rosiptor Boc-His(Trt)-Aib-OH Octadecanedioic acid mono-tert-butyl ester Fmoc-8-amino-3,6-dioxaoctanoic acid

  • (S)-22-(Tert-butoxycarbonyl)-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontane-1,41-dioic acid
  • Octadecane(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH
  • Side chain
  • tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
  • Semaglutide side chain
  • Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OHu
  • (S)-22-(tert-butoxycarbonyl)-43,43-dimethyl-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontanoic acid
  • Egf(a) analogue-13C4
  • 3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid, 22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-, 41-(1,1-dimethylethyl) ester, (22S)-
  • tBuO-Ste-Glu(AEEA-AEEA)-OtBu
  • Octa(OtBu)-Glu(AEEA-AEEA-OH)-OtBu
  • Octadecane(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH
  • Octadecane(OtBu)-Glu( α -OtBu)-AEEA-AEEA- OH
  • TBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu/ Semaglutide Side Chain
  • Somaluptide side chain
  • intermediates of semaglutide
  • PEG2-PEG2-(γ-Glu-tBu)-17-carboxyheptadecanoyl-tBu
  • tBuO-Ste-E(AEEA-AEEA-OH)OtBu
  • (S)-22-(tert-butoxycarbonyl)-30,30-dimethyl-10,19,24,28-tetraoxo-3,6,12,15,29-pentaoxa-9,18,23-triazahentriacontanoic acid
  • Carbaryl Impurity 3
  • tBuO-Ste-γGlu(OtBu)-AEEA- AEEA-OH
  • tBuO-Ste-rGlu(OtBu)-AEEA-AEEA-OH
  • 3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid, 22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-,41-(1,1-dimethylethyl) ester
  • 2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(18-tert-butoxy-18-oxo-octadecanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetic acid
  • Semaglutide impurity 22
  • tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu (DMF solution)
  • Semaglutide side chain-tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu
  • Semaglutide linker
  • tBuO-Ste-y-Glu(AEEA-AEEA-OH)-OtBu
  • tBuO-ste-Glu(AEEA-AEEA- 0 H) -otBu
  • 1118767-16-0
  • C43H79N3O13