ChemicalBook > CAS DataBase List > 5-Hydroxyisophthalic acid

5-Hydroxyisophthalic acid

Product Name: 5-Hydroxyisophthalic acid
CAS No.: 618-83-7
Chemical Name: 5-Hydroxyisophthalic acid
Synonyms: OHIPA;5-HIPA;5-HydroxyisophthaL;3,5-Dicarboxyphenol;5-Hydroxy Isophthalate;5-hydroxy-isophthalicaci;5-HYDROXYISOPTHALIC ACID;5-HYDROXYISOPHTHALIC ACID;HYDROXYISOPHTHALIC-5 ACID;5-Hydroxy-m-phthalic acid
CBNumber: CB4412793
Molecular Formula: C8H6O5
Formula Weight: 182.13
MOL File: 618-83-7.mol

Less

5-Hydroxyisophthalic acid Property

Melting point:: 298-302 °C (lit.)
Boiling point:: 235.5°C (rough estimate)
Density: 1.3293 (rough estimate)
vapor pressure: 0Pa at 25℃
refractive index: 1.4330 (estimate)
storage temp.: Store below +30°C.
solubility: 0.6g/l
form: Powder
pka: 3.41±0.10(Predicted)
color: White to slightly yellow
PH: <7 (H2O, 20℃)
Water Solubility: 0.6g/L(15 ºC)
BRN: 2693561
Dissociation constant: 0-0 at 23℃
CAS DataBase Reference: 618-83-7(CAS DataBase Reference)
EPA Substance Registry System: 5-Hydoxyisophthalic acid (618-83-7)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-24/25-36
WGK Germany: 2
RTECS: CZ4280000
TSCA: Yes
HS Code: 29182990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 311278
Product name: 5-Hydroxyisophthalic acid
Purity: 97%
Packaging: 100g
Price: $87.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.40013
Product name: 5-Hydroxyisophthalic acid
Purity: for synthesis
Packaging: 50g
Price: $90.5
Updated: 2022/05/15

TCI Chemical

Product number: H0794
Product name: 5-Hydroxyisophthalic Acid
Purity: >97.0%(T)
Packaging: 25g
Price: $64
Updated: 2025/07/31

TCI Chemical

Product number: H0794
Product name: 5-Hydroxyisophthalic Acid
Purity: >97.0%(T)
Packaging: 500g
Price: $622
Updated: 2025/07/31

TRC

Product number: H943485
Product name: 5-Hydroxyisophthalic Acid
Packaging: 10g
Price: $85
Updated: 2021/12/16

Less

5-Hydroxyisophthalic acid Chemical Properties,Usage,Production

Chemical Properties

white to slightly yellow powder

Uses

5-Hydroxyisophthalic Acid is used as a reagent in the synthesis of silver carboxylate metal organic framework (MOF) complexes. 5-Hydroxyisophthalic Acid is also used as the starting material in the synthesis of N,NтАЩ-Bis(2,3-dihydroxypropyl)-5-[(N-(2-hydroxyethyl)carbamoyl)methoxy]-2,4,6-triiodoisophthalamide (B426310); a compound related to Ioversol( I737000) which is a nonionic, low osmolality, radiographic contrast agent.

General Description

The hydrothermal reaction of 5-hydroxyisophthalic acid, Co(II)/Cu(II) and dipyridophenazine, that forms two 3D chiral coordination polymers, was studied.

Synthesis

13036-02-7

618-83-7

The general procedure for the synthesis of 5-hydroxyisophthalic acid from dimethyl 5-hydroxyisophthalate was as follows: dimethyl 5-hydroxyisophthalate (40 g, 19.03 mmol) was dissolved in THF (10 mL), followed by the addition of aqueous lithium hydroxide (20 mL, 2 M). The reaction mixture was stirred at 40 °C overnight. Upon completion of the reaction, THF was removed by distillation under reduced pressure. the pH of the remaining aqueous solution was adjusted to about 2 with 6N hydrochloric acid to precipitate the product. The precipitated 5-hydroxyisophthalic acid was collected by filtration and dried in a vacuum oven to give 20 g of white solid product in 58% yield.

References

[1] Patent: WO2010/78449, 2010, A2. Location in patent: Page/Page column 317

5-Hydroxyisophthalic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Less

5-Hydroxyisophthalic acid Suppliers

Americas 1 Belgium 3 China 261 Czech Republic 3 Europe 4 Finland 1 France 1 Germany 8 India 18 Italy 1 Japan 10 Slovakia 1 South Korea 1 Switzerland 2 Ukraine 2 United Kingdom 12 United States 40 Global 369

Zhengzhou Alfachem Co.,Ltd.

Tel: 0371-53778726 18003825608
Fax: QQ：2885354392
Email: liuxiaoyan@alfachem.cn
Country: China
ProdList: 1987
Advantage: 58

Huaihua Baohua Biological Technology Co. LTD

Tel: 0519-82698292
Email: info@hhbhswkj.com
Country: China
ProdList: 134
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2805
Advantage: 65

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
Country: China
ProdList: 2816
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527621225
Email: 1791901229@qq.com
Country: China
ProdList: 6945
Advantage: 52

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3295
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Nanjing Vital Chemical Co., Ltd.

Tel: Please Send Email 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 4378
Advantage: 65

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6134
Advantage: 55

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4566
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2930
Advantage: 58

RiZhao LiDeShi Chemical Co., Ltd.

Tel: 010-51268198
Fax: 010-63833209
Email: leadershipchem@126.com
Country: China
ProdList: 2546
Advantage: 58

Zhengzhou HongSheng Pharmaceutical Co., Ltd.

Tel: 0371-0371-13526885213 15637198702
Fax: 0371-63709726
Email: hsyykjchem@163.com
Country: China
ProdList: 3853
Advantage: 58

Mei Lan Industrial (Shanghai) Co., Ltd.

Tel: 021-58958189
Fax: 021-58957967
Email: wouchina@126.com
Country: China
ProdList: 2666
Advantage: 55

Shanghai ideal Industrial Co., Ltd.

Tel: 021-58957966 18930537195
Fax: 021-60899437
Email: wouchina@126.com
Country: China
ProdList: 3027
Advantage: 58

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

GuangTuo Chemical (Shanghai) Co., Ltd.

Tel: 021-60899189-8001 18918189673
Fax: 021-60899304
Email: gtchem@126.com
Country: China
ProdList: 2656
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.

Tel: 021-69106960 13701823733
Fax: 021-69106780
Email: 13701823733@163.com
Country: China
ProdList: 4641
Advantage: 60

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Less

View Lastest Price from 5-Hydroxyisophthalic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 5-Hydroxyisophthalic acid 618-83-7
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-05

Shaanxi Dideu New Materials Co. Ltd

Product: 5-Hydroxyisophthalic acid 618-83-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 10000KGS
Release date: 2025-02-18

Wuhan Boyuan Import & Export Co., LTD

Product: 5-Hydroxyisophthalic acid 618-83-7
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000tons
Release date: 2023-06-06

618-83-7, 5-Hydroxyisophthalic acidRelated Search:

5-Aminoisophthalic acid 4-Hydroxybenzoic acid 2'-Hydroxy-3-phenylpropiophenone Ethyl 2-(Chlorosulfonyl)acetate Methylparaben 3-Hydroxybenzoic acid Isopropylparaben Butylparaben CHLOROPHOSPHONAZO III Folic acid (±)-HIP-A SALICYLIC ACID, IMP. B (EP): 4-HYDROXYISOPHTHALIC ACID MM(CRM STANDARD) Isophthalic acid Citric acid Ascoric Acid 5-(OCTADECYLOXY)ISOPHTHALIC ACID 5-METHOXYISOPHTHALIC ACID 5-HYDROXYISOPHTHALIC ACID DIMETHYL,Dimethyl 5-hydroxybenzene-1,3-dicarboxylate~5-Hydroxyisophthalic acid dimethyl ester,5-HYDROXYISOPHTHALIC ACID DIMETHYL ESTER

OHIPA

5-hydroxy-3-benzenedicarboxylicacid

5-hydroxy-isophthalicaci

5-HYDROXYBENZENE-1,3-DICARBOXYLIC ACID

5-HYDROXYISOPHTHALIC ACID

5-HYDROXYISOPTHALIC ACID

5-HIPA

5-HYDROXY-1,3-BENZENEDICARBOXYLIC ACID

HYDROXYISOPHTHALIC-5 ACID

HYDROXYISOPHTHALIC ACID, 5-

5-Hydroxyisophthalic acid high quality(618-83-7)

5-HydroxyisophthaL

5-hydroxybenzene-1,3-dicarboxylate

sym-Hydroxy-iso-phthalicacid

5-Hydroxy-m-phthalic acid

5-Hydroxy-1,3-benzenedicarboxy

5-HYDROXYISOPHTHHALIC ACID

5-Hydroxy Isophthalate

5-Hydroxy isophtalic acid

3,5-Dicarboxyphenol

5-Hydroxyisophthalic acid, 99% 100GR

5-Hydroxyisophthalic acid, 99% 25GR

5-Hydroxyisophthalic acid, 99% 500GR

5-Hydroxybenzene-1,3-dicarboxylic acid, 3,5-Dicarboxyphenol

5- hydroxybenzene between two forMic acid

5-HydroxyisophthalicAcid&gt

5-HYDROXYISOPHTHALIC ACID FOR SYNTHESIS

1,3-Benzenedicarboxylic acid, 5-hydroxy-

5-HYDROXYISOPHTHALIC ACID (5-HIPA)

618-83-7

C8H6O5

HOC6H313CO2H2

Building Blocks for Dendrimers

Organic Building Blocks

Carbonyl Compounds

Carboxylic Acids

Building Blocks

Phthalic Acids, Esters and Derivatives

Organic acids

Building Blocks for Dendrimers

Functional Materials

Benzene derivatives

Carbonyl Compounds

Carboxylic Acids