ChemicalBook > CAS DataBase List > (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride

(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride

Product Name
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
CAS No.
101152-94-7
Chemical Name
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
Synonyms
IXEL;F 2207;TOLEDOMIN;Dalcipran;cis-(+-)-d;MIDALCIPRAN;MLNACIPRAM HCL;Milnacipran HCI;Chiral Reagents;MILNACIPRAN HCL
CBNumber
CB4423243
Molecular Formula
C15H23ClN2O
Formula Weight
282.81
MOL File
101152-94-7.mol
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(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Property

Melting point:
179-1810C
Flash point:
9℃
storage temp. 
2-8°C
solubility 
H2O: 19 mg/mL
form 
solid
color 
white
Water Solubility 
H2O: 19mg/mL
Merck 
14,6194
CAS DataBase Reference
101152-94-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
22-39/23/24/25-23/24/25-11
Safety Statements 
7-16-36/37-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
GZ1014010
HazardClass 
6.1
PackingGroup 
III
HS Code 
29242990
Toxicity
LD50 orally in mice: 237 mg/kg (Bonnaud)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M-145
Product name
Milnacipran hydrochloride solution
Purity
1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$213
Updated
2024/03/01
Sigma-Aldrich
Product number
M1318
Product name
Milnacipran hydrochloride
Purity
≥98% (HPLC), solid
Packaging
10mg
Price
$242
Updated
2024/03/01
Sigma-Aldrich
Product number
M1318
Product name
Milnacipran hydrochloride
Purity
≥98% (HPLC), solid
Packaging
50mg
Price
$526.2
Updated
2024/03/01
TCI Chemical
Product number
M2133
Product name
Milnacipran Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
50mg
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
M2133
Product name
Milnacipran Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
500mg
Price
$94
Updated
2024/03/01
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(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

antibacterial

Uses

Antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.

Definition

ChEBI: Milnacipran hydrochloride is a member of acetamides.

General Description

Milnacipran, sold under the brand names Savella?, Ixel?, Dalcipran?, or Toledomin, is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the treatment of depression. In 2009, the US Food and Drug Administration (FDA) approved milnacipran for management of the chronic pain disorder fibromyalgia, making it only the third drug approved in the US for this indication besides duloxetine and pregabalin.

Biological Activity

Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .

Biochem/physiol Actions

Serotonin and norepinephrine reuptake inhibitor (SNRI)

storage

+4°C

(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Suppliers

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View Lastest Price from (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Milnacipran hydrochloride solution 101152-94-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Milnacipran hydrochloride solution 101152-94-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
Milnacipran Hydrochloride 101152-94-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

101152-94-7, (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochlorideRelated Search:

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