E-64C

Product Name: E-64C
CAS No.: 76684-89-4
Chemical Name: E-64C
Synonyms: E-64C;NSC 694279;E-64c, EP 475;Loxistatin acid;anecarboxylicacid;ep475(enzymeinhibitor);Loxistatin Acid (E-64C);Inhibitorforthiolprotease;NSC 694279 Loxistatin Acid;E-64-c Loxistatin acid NSC 694279
CBNumber: CB4425580
Molecular Formula: C15H26N2O5
Formula Weight: 314.38
MOL File: 76684-89-4.mol

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E-64C Property

storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: ≥31.4 mg/mL in DMSO; insoluble in H2O; ≥111.8 mg/mL in EtOH
form: White to off-white solid
color: White to off-white
InChIKey: SCMSYZJDIQPSDI-SRVKXCTJSA-N

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Safety

WGK Germany: 3
RTECS: RR0404200
HS Code: 29241990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10007964
Product name: E-64c
Purity: ≥98%
Packaging: 1mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 10007964
Product name: E-64c
Purity: ≥98%
Packaging: 5mg
Price: $270
Updated: 2024/03/01

Cayman Chemical

Product number: 10007964
Product name: E-64c
Purity: ≥98%
Packaging: 10mg
Price: $477
Updated: 2024/03/01

Cayman Chemical

Product number: 10007964
Product name: E-64c
Purity: ≥98%
Packaging: 25mg
Price: $1041
Updated: 2024/03/01

TRC

Product number: E100495
Product name: E-64c
Packaging: 25mg
Price: $875
Updated: 2021/12/16

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E-64C Chemical Properties,Usage,Production

Description

E-64c is an active metabolite of the protease inhibitor E-64d . E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when used at concentrations ranging from 0.1 to 1 mg/ml. E-64c reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) surface glycoprotein, also known as the spike glycoprotein, in a concentration-dependent manner.

Uses

E-64c is a cysteine protease inhibitor used for detecting autophagy in plants.

Definition

ChEBI: E-64c is a leucine derivative.

target

cathepsins B

E-64C Preparation Products And Raw materials

Raw materials

Preparation Products

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E-64C Suppliers

China 92 France 1 Germany 2 Japan 1 Switzerland 1 United Kingdom 1 United States 16 USA 1 Global 115

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Alabiotech Inc.

Tel: 001-619-354-5251
Fax: 001-855-855-6087
Email: sales@alabiotech-e.com
Country: United States
ProdList: 972
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

ApexBio Technology

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Country: United States
ProdList: 6251
Advantage: 58

Alfa Chemistry

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Country: United States
ProdList: 6814
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Cayman Chemical Company

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Country: United States
ProdList: 6213
Advantage: 81

United States Biological

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ProdList: 6214
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MedChemExpress

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Country: United States
ProdList: 6398
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Riedel-de Haen AG

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ProdList: 6773
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Matrix Scientific

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Santa Cruz Biotechnology, Inc.

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Country: United States
ProdList: 3597
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BIOMOL INTERNATIONAL, LP

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Chem-Impex International, Inc.

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ProdList: 6730
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View Lastest Price from E-64C manufacturers

Career Henan Chemical Co

Product: E-64C;NSC 694279 Loxistatin Acid 76684-89-4
Price: US $0.01/KG
Min. Order: 1KG
Purity: 98%; 99%
Supply Ability: 1kg；10kg; 25kg
Release date: 2020-01-07

76684-89-4, E-64CRelated Search:

2-Hydroxy-4-amino butanoic acid (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID BUTTPARK 37\11-64 GLYCIDAMIDE EST BUTTPARK 45\03-64 BUTTPARK 44\01-64 BUTTPARK 36\08-64 BUTTPARK 45\03-64 BUTTPARK 43\57-64 (2-amino-2-oxoethoxy)acetic acid E-64C (2-AMINO-ETHOXY)-ACETIC ACID 2(2-HYDROXYETHOXY)ACETAMIDE BUTTPARK 62\07-64 BUTTPARK 51\09-64 BUTTPARK 64\41-01 BUTTPARK 46\18-64

(2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE

(2S,3S)-L-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE

(2S,3S)-3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylic acid

2-Oxiranecarboxylicacid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)-

Loxistatin Acid (E-64C)

NSC 694279

E-64c, EP 475

(1S,2S)-2-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)cyclopropanecarboxylic

(L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCINE (3-METHYLBUTYL)AMIDE

E-64C

L-TRANS-EPOXYSUCCINYL-LEU-3-METHYLBUTYLAMIDE

E-64-c Loxistatin acid NSC 694279

(+)-(2s,3s)-3-((s)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxir

(2s-(2-alpha,3-beta(r*)))-mino)carbonyl)

anecarboxylicacid

ep475(enzymeinhibitor)

oxiranecarboxylicacid,3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)a

(2S,3S)-TRANS-EPOXYSUCCINYL-L-*LEUCYLAMI DO-3-METHYL

Inhibitorforthiolprotease

(2S)-3β-[[[(S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2α-oxiranecarboxylic acid

(2S,3S)-3-[[(1S)-1-(3-Methylbutylcarbamoyl)-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid

Loxistatin acid

NSC 694279 Loxistatin Acid

NSC 694279 LOXISTATIN ACID; EP 475;E64C;E 64C

76684-89-4

BioChemical

Calpain

A to C

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Enzyme

Enzyme Inhibitors

Biochemicals and Reagents

Pepetides

Inhibitors

peptides