β-Boswellic Acid
- Product Name
- β-Boswellic Acid
- CAS No.
- 631-69-6
- Chemical Name
- β-Boswellic Acid
- Synonyms
- BRN0077366;Masticinic acid;B-BOSWELLIC ACID;Β-BOSWELLIC ACID;β-Boswellic Acid;BOSWELLIC ACID, B-;BETA-BOSWELLIC ACID;BOSWELLIC ACID, a-(P);β-Boswellic Acid USP/EP/BP;NBGQZFQREPIKMG-PONOSELZSA-N
- CBNumber
- CB4427357
- Molecular Formula
- C30H48O3
- Formula Weight
- 456.71
- MOL File
- 631-69-6.mol
β-Boswellic Acid Property
- Melting point:
- 130-135°C
- alpha
- D +107° (c = 0.75 in CHCl3)
- Boiling point:
- 556.0±50.0 °C(Predicted)
- Density
- 1.09±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- pka
- 4.50±0.70(Predicted)
- color
- Off-White
- Water Solubility
- practically insoluble in water
- InChIKey
- NBGQZFQREPIKMG-AKOQEMLPSA-N
- LogP
- 9.105 (est)
- CAS DataBase Reference
- 631-69-6
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 80342
- Product name
- β-Boswellic acid
- Purity
- analytical standard
- Packaging
- 5mg
- Price
- $561
- Updated
- 2024/03/01
- Product number
- 11693
- Product name
- β-Boswellic Acid
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 11693
- Product name
- β-Boswellic Acid
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $183
- Updated
- 2024/03/01
- Product number
- 11693
- Product name
- β-Boswellic Acid
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $321
- Updated
- 2024/03/01
- Product number
- 361758
- Product name
- Beta-Boswellic acid
- Packaging
- 10mg
- Price
- $632
- Updated
- 2021/12/16
β-Boswellic Acid Chemical Properties,Usage,Production
Description
β-Boswellic acid is a pentacyclic triterpene originally isolated from Boswellia that has diverse bioactivities. It inhibits 5-lipoxygenase (5-LO) with an IC50 value of approximately 5 μM but is less potent than its derivative 3-acetyl-11-keto-β-boswellic acid . It inhibits cell proliferation in HL-60 cells with IC50 values of 3.7, 7.1, and 6.3 μM for DNA, RNA, and protein synthesis, respectively. In human umbilical vein endothelial cells (HUVECs) transiently deprived of oxygen and glucose, β-boswellic acid increases nitric oxide and increases phosphorylation of enzyme nitric oxide synthase (eNOS). It also increases calcium mobilization in platelets at concentrations ≥3 μM and induces platelet aggregation (EC50 = 8 μM).
Chemical Properties
BETA-BOSWELLIC ACID is Off-White Solid
Uses
The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.
Definition
ChEBI: Boswellic acid is a triterpenoid.
Anticancer Research
It is a natural pentacyclic triterpenediol and occurs in Boswellia serrata plants as anisomeric blend of 3α, 24-dihydroxyolean-12-ene and 3α, 24-dihydroxyurs-12-ene.It induces apoptosis in various cancer cells. The events involved in this process areexcessive reactive oxygen species (ROS), nitric oxide (NO) formation, DNA ladderformation, and increased sub-G0 phase in cell cycle. This ultimately results incleavage of Bcl-2 and translocation of Bax to mitochondria, which lead to the lossof mitochondrial potential and release of cyt-c and other factors into cytosol. All these events are linked with reduced expression of survivin and inhibitor of caspase-activatedDNases (ICAD) that leads to the activation of poly(ADP-ribose) polymerase(PARP). The triterpene upregulates the expression of cell death receptor-4(DR-4) and tumor necrosis factor receptor-1 (TNF-R1), where both lead to activationof caspase-8 (Huang et al. 2000; Desai et al. 2008; Lu et al. 2008).
β-Boswellic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from β-Boswellic Acid manufacturers
- Product
- β-Boswellic Acid 631-69-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- >99% HPLC
- Supply Ability
- 1000KG
- Release date
- 2022-09-22
- Product
- β-Boswellic Acid 631-69-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-10-10
- Product
- β-Boswellic Acid 631-69-6
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2023-03-22