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β-Boswellic Acid

Product Name
β-Boswellic Acid
CAS No.
631-69-6
Chemical Name
β-Boswellic Acid
Synonyms
BRN0077366;Masticinic acid;Frankincic acid;B-BOSWELLIC ACID;Β-BOSWELLIC ACID;β-Boswellic Acid;BOSWELLIC ACID, B-;BETA-BOSWELLIC ACID;BOSWELLIC ACID, a-(P);BOSWELLIC ACID B-(P) 25mg
CBNumber
CB4427357
Molecular Formula
C30H48O3
Formula Weight
456.71
MOL File
631-69-6.mol
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β-Boswellic Acid Property

Melting point:
130-135°C
alpha 
D +107° (c = 0.75 in CHCl3)
Boiling point:
556.0±50.0 °C(Predicted)
Density 
1.09±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
4.50±0.70(Predicted)
color 
Off-White
Water Solubility 
practically insoluble in water
InChIKey
NBGQZFQREPIKMG-AKOQEMLPSA-N
LogP
9.105 (est)
CAS DataBase Reference
631-69-6
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
80342
Product name
β-Boswellic acid
Purity
analytical standard
Packaging
5mg
Price
$561
Updated
2024/03/01
Cayman Chemical
Product number
11693
Product name
β-Boswellic Acid
Purity
≥95%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
11693
Product name
β-Boswellic Acid
Purity
≥95%
Packaging
5mg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
11693
Product name
β-Boswellic Acid
Purity
≥95%
Packaging
10mg
Price
$321
Updated
2024/03/01
Usbiological
Product number
361758
Product name
Beta-Boswellic acid
Packaging
10mg
Price
$632
Updated
2021/12/16
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β-Boswellic Acid Chemical Properties,Usage,Production

Description

β-Boswellic acid is a pentacyclic triterpene originally isolated from Boswellia that has diverse bioactivities. It inhibits 5-lipoxygenase (5-LO) with an IC50 value of approximately 5 μM but is less potent than its derivative 3-acetyl-11-keto-β-boswellic acid . It inhibits cell proliferation in HL-60 cells with IC50 values of 3.7, 7.1, and 6.3 μM for DNA, RNA, and protein synthesis, respectively. In human umbilical vein endothelial cells (HUVECs) transiently deprived of oxygen and glucose, β-boswellic acid increases nitric oxide and increases phosphorylation of enzyme nitric oxide synthase (eNOS). It also increases calcium mobilization in platelets at concentrations ≥3 μM and induces platelet aggregation (EC50 = 8 μM).

Chemical Properties

BETA-BOSWELLIC ACID is Off-White Solid

Uses

The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.

Definition

ChEBI: Boswellic acid is a triterpenoid.

Anticancer Research

It is a natural pentacyclic triterpenediol and occurs in Boswellia serrata plants as anisomeric blend of 3α, 24-dihydroxyolean-12-ene and 3α, 24-dihydroxyurs-12-ene.It induces apoptosis in various cancer cells. The events involved in this process areexcessive reactive oxygen species (ROS), nitric oxide (NO) formation, DNA ladderformation, and increased sub-G0 phase in cell cycle. This ultimately results incleavage of Bcl-2 and translocation of Bax to mitochondria, which lead to the lossof mitochondrial potential and release of cyt-c and other factors into cytosol. All these events are linked with reduced expression of survivin and inhibitor of caspase-activatedDNases (ICAD) that leads to the activation of poly(ADP-ribose) polymerase(PARP). The triterpene upregulates the expression of cell death receptor-4(DR-4) and tumor necrosis factor receptor-1 (TNF-R1), where both lead to activationof caspase-8 (Huang et al. 2000; Desai et al. 2008; Lu et al. 2008).

β-Boswellic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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β-Boswellic Acid Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
ProdList
96815
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
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3bsc@sina.com
Country
China
ProdList
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Chembest Research Laboratories Limited
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+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
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China
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Chemsky(shanghai)International Co.,Ltd.
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021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
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ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
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021-55068248
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shyysw007@163.com
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T&W GROUP
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021-61551611 13296011611
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+86 21-50676805
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contact@trustwe.com
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Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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+86-28-82633165
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cwb1@biopurify.cn
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China
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Shanghai Tauto Biotech Co., Ltd.
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021-51320588
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0086-21-51320502
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tauto@tautobiotech.com
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China
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3989
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66
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
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marketing@targetmol.com
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China
ProdList
7783
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Shanghai BeiZhuo Biotech Co., Ltd.
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021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
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50
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View Lastest Price from β-Boswellic Acid manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
β-Boswellic Acid 631-69-6
Price
US $0.00/KG
Min. Order
1KG
Purity
>99% HPLC
Supply Ability
1000KG
Release date
2022-09-22
Hebei Zhuanglai Chemical Trading Co Ltd
Product
β-Boswellic Acid 631-69-6
Price
US $79.00-38.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-11-21
Hebei Weibang Biotechnology Co., Ltd
Product
β-Boswellic Acid 631-69-6
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04

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