ChemicalBook > CAS DataBase List > β-Boswellic Acid

β-Boswellic Acid

Product Name
β-Boswellic Acid
CAS No.
631-69-6
Chemical Name
β-Boswellic Acid
Synonyms
BRN0077366;Masticinic acid;Frankincic acid;B-BOSWELLIC ACID;β-Boswellic Acid;BOSWELLIC ACID, B-;BETA-BOSWELLIC ACID;BOSWELLIC ACID, a-(P);BOSWELLIC ACID B-(P) 25mg;β-Boswellic Acid USP/EP/BP
CBNumber
CB4427357
Molecular Formula
C30H48O3
Formula Weight
456.71
MOL File
631-69-6.mol
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β-Boswellic Acid Property

Melting point:
130-135°C
alpha 
D +107° (c = 0.75 in CHCl3)
Boiling point:
556.0±50.0 °C(Predicted)
Density 
1.09±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
4.50±0.70(Predicted)
color 
Off-White
Water Solubility 
practically insoluble in water
InChIKey
NBGQZFQREPIKMG-AKOQEMLPSA-N
LogP
9.105 (est)
CAS DataBase Reference
631-69-6
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
80342
Product name
β-Boswellic acid
Purity
analytical standard
Packaging
5mg
Price
$561
Updated
2024/03/01
Cayman Chemical
Product number
11693
Product name
β-Boswellic Acid
Purity
≥95%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
11693
Product name
β-Boswellic Acid
Purity
≥95%
Packaging
5mg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
11693
Product name
β-Boswellic Acid
Purity
≥95%
Packaging
10mg
Price
$321
Updated
2024/03/01
Usbiological
Product number
361758
Product name
Beta-Boswellic acid
Packaging
10mg
Price
$632
Updated
2021/12/16
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β-Boswellic Acid Chemical Properties,Usage,Production

Description

β-Boswellic acid is a pentacyclic triterpene originally isolated from Boswellia that has diverse bioactivities. It inhibits 5-lipoxygenase (5-LO) with an IC50 value of approximately 5 μM but is less potent than its derivative 3-acetyl-11-keto-β-boswellic acid . It inhibits cell proliferation in HL-60 cells with IC50 values of 3.7, 7.1, and 6.3 μM for DNA, RNA, and protein synthesis, respectively. In human umbilical vein endothelial cells (HUVECs) transiently deprived of oxygen and glucose, β-boswellic acid increases nitric oxide and increases phosphorylation of enzyme nitric oxide synthase (eNOS). It also increases calcium mobilization in platelets at concentrations ≥3 μM and induces platelet aggregation (EC50 = 8 μM).

Chemical Properties

BETA-BOSWELLIC ACID is Off-White Solid

Uses

The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.

Definition

ChEBI: Boswellic acid is a triterpenoid.

Anticancer Research

It is a natural pentacyclic triterpenediol and occurs in Boswellia serrata plants as anisomeric blend of 3α, 24-dihydroxyolean-12-ene and 3α, 24-dihydroxyurs-12-ene.It induces apoptosis in various cancer cells. The events involved in this process areexcessive reactive oxygen species (ROS), nitric oxide (NO) formation, DNA ladderformation, and increased sub-G0 phase in cell cycle. This ultimately results incleavage of Bcl-2 and translocation of Bax to mitochondria, which lead to the lossof mitochondrial potential and release of cyt-c and other factors into cytosol. All these events are linked with reduced expression of survivin and inhibitor of caspase-activatedDNases (ICAD) that leads to the activation of poly(ADP-ribose) polymerase(PARP). The triterpene upregulates the expression of cell death receptor-4(DR-4) and tumor necrosis factor receptor-1 (TNF-R1), where both lead to activationof caspase-8 (Huang et al. 2000; Desai et al. 2008; Lu et al. 2008).

β-Boswellic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from β-Boswellic Acid manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
β-Boswellic Acid 631-69-6
Price
US $0.00/KG
Min. Order
1KG
Purity
>99% HPLC
Supply Ability
1000KG
Release date
2022-09-22
Hebei Mujin Biotechnology Co.,Ltd
Product
β-Boswellic Acid 631-69-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-10
Hebei Zhuanglai Chemical Trading Co Ltd
Product
β-Boswellic Acid 631-69-6
Price
US $79.00-38.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-11-21

631-69-6, β-Boswellic AcidRelated Search:

Carbenoxolone OLIBANUM GUM β-Elemonic Acid (3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid BOSWELLIC ACID, B-(P) ACETYL-B-BOSWELLIC ACID, 3-(P) ACETYL-A-BOSWELLIC ACID, 3-(P) ALPHA-BOSWELLIC ACID 11-KETO-BETA-BOSWELLIC ACID 3-ACETYL-11-KETO-BETA-BOSWELLIC ACID,3-O-ACETYL-11-KETO-BETA-BOSWELLIC ACID,ACETYL-11-KETO-BETA-BOSWELLIC ACID BETA-BOSWELLIC ACID BRASSIDIC ACID 3-ACETYL-BETA-BOSWELLIC ACID URS-12(13)-ENE Erucic Acid

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  • B-BOSWELLIC ACID
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  • Beta-BoswellicAcidforU.Lingner-HoffmannCHEMOSGmbHsales
  • (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picene-4-carboxylic acid
  • BOSWELLIC ACID, a-(P)
  • (3A,4B)-3-HYDROXYURS-12-EN-23-OIC ACID
  • (3a,4)-3-Hydroxyurs-12-en-23-oic Acid
  • (3α,4β)-3-Hydroxyurs-12-en-23-oic Acid
  • 3-Hydroxy-12-ursen-24-oic acid
  • 3α-Hydroxyurs-12-en-24-oic acid
  • NBGQZFQREPIKMG-PONOSELZSA-N
  • Soluble BOSWELLIC ACID, Liposomal BOSWELLIC ACID, BOSWELLIC ACID NanoEmulsion, NanoActive BOSWELLIC ACID, BETA-BOSWELLIC ACID,Boswellia sacra
  • Soluble BOSWELLIC ACID, Liposomal BOSWELLIC ACID, BOSWELLIC ACID NanoEmulsion, NanoActive BOSWELLIC ACID, BETA-BOSWELLIC ACID
  • Urs-12-en-23-oic acid, 3-hydroxy-, (3α,4β)-
  • β-Boswellic Acid USP/EP/BP
  • Masticinic acid
  • BRN0077366
  • β-Boswellic Acid
  • BOSWELLIC ACID B-(P) 25mg
  • Frankincic acid
  • β-Boswellic acid, 10 mM in DMSO
  • 631-69-6
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