ChemicalBook > CAS DataBase List > 3-Acetylthiophene

3-Acetylthiophene

Product Name
3-Acetylthiophene
CAS No.
1468-83-3
Chemical Name
3-Acetylthiophene
Synonyms
3-Acetyl;3-Acetylthioph;Acetylthiophene;Acetylthio[hene;3-Acetylthiophen;3-ACETYLTHIOPHENE;Acetylthiophene,97%;Acetylthiophene,95%;3-Acetylthiophene99%;1-thien-3-ylethanone
CBNumber
CB4434894
Molecular Formula
C6H6OS
Formula Weight
126.18
MOL File
1468-83-3.mol
More
Less

3-Acetylthiophene Property

Melting point:
57-62 °C (lit.)
Boiling point:
208-210 °C/748 mmHg (lit.)
Density 
1.176 (estimate)
refractive index 
1.5667 (estimate)
Flash point:
208-210°C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Hexane (Slightly)
form 
Adhering Crystals
color 
Beige to light brown
Sensitive 
Light Sensitive
BRN 
107241
InChIKey
RNIDWJDZNNVFDY-UHFFFAOYSA-N
LogP
1.240
CAS DataBase Reference
1468-83-3(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(3-thienyl)-(1468-83-3)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-24/25-36/37-36-26
RIDADR 
UN2811
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
196320
Product name
3-Acetylthiophene
Purity
98%
Packaging
10g
Price
$129
Updated
2025/07/31
TCI Chemical
Product number
A1006
Product name
3-Acetylthiophene
Purity
>95.0%(GC)
Packaging
10g
Price
$115
Updated
2025/07/31
TCI Chemical
Product number
A1006
Product name
3-Acetylthiophene
Purity
>95.0%(GC)
Packaging
25g
Price
$166
Updated
2023/01/07
TRC
Product number
A188800
Product name
3-Acetylthiophene
Packaging
50g
Price
$470
Updated
2021/12/16
TRC
Product number
A188800
Product name
3-Acetylthiophene
Packaging
10g
Price
$120
Updated
2021/12/16
More
Less

3-Acetylthiophene Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

3-Acetylthiophene was used in the preparation of 1-(methylthiophenylidine)-8-naphthylamine(Schiff′s base) and 1-(thiophen-3-yl)ethanone.

Definition

ChEBI: 3-Acetylthiophene is an aromatic ketone.

General Description

3-Acetylthiophene modified glassy carbon electrode has been used in voltammetric determination of uric acid in urine samples.

Synthesis

67237-53-0

1468-83-3

The general procedure for the synthesis of 3-acetylthiophene from 3-ethynylthiophene was as follows: a mixture of 3-ethynylthiophene (232 mg, 2.0 mmol) and S-COPNA (NP) resin (59 mg, 0.2 mmol) in H2O (4 mL) was subjected to refluxing conditions (bath temperature of 120°C) and the reaction was stirred for 8 h at 600 rpm. After completion of the reaction, the catalyst was removed by filtration and washed sequentially with H2O and heptane. A drop of saturated NaHCO3 solution was added to the organic layer, followed by evaporation of the organic solvent under reduced pressure. The residue was purified by column chromatography using heptane-acetone (20:1) as eluent to give finally 3-acetylthiophene (225 mg, 84% yield).

Purification Methods

Recrystallise the thiophene from pet ether (b 30-60o) or EtOH. The 2,4-dinitrophenylhydrazone crystallises from CHCl3, m 265o, and the semicarbazone crystallises from EtOH, m 174-175o. [Campaigne & Le Suer J Am Chem Soc 70 1555 1948, Beilstein 17/9 V 399.]

References

[1] Applied Organometallic Chemistry, 2012, vol. 26, # 12, p. 722 - 726
[2] Tetrahedron Letters, 2017, vol. 58, # 10, p. 955 - 958
[3] Tetrahedron Letters, 2014, vol. 55, # 8, p. 1444 - 1447
[4] ChemSusChem, 2013, vol. 6, # 3, p. 430 - 432

3-Acetylthiophene Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-Acetylthiophene Suppliers

Americas 1 Belgium 2 Canada 1 China 226 Europe 3 France 1 Germany 12 India 30 Japan 5 Slovakia 3 Switzerland 3 The Netherlands 1 United Kingdom 23 United States 51 USA 1 Global 363
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376080562
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
884
Advantage
60
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94644
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 18982182443
Email
yangli@happysyn.com
Country
China
ProdList
2151
Advantage
55
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shenzhen Pharma Technology Co., Ltd.
Tel
0755-86648230
Fax
0755-86648231
Email
pharma08@sina.com
Country
China
ProdList
166
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4924
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2930
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
6295
Advantage
60
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4641
Advantage
60
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Beijing Xinsavi Chemical Technology Co., Ltd.
Tel
010-56218822 13717722232
Fax
010-56218800
Email
xinsavichem@163.com
Country
China
ProdList
3201
Advantage
56
Beijing Holiyang Chemical Co. Ltd.
Tel
13718199399
Fax
QQ : 206661479
Email
holiyangchem@163.com
Country
China
ProdList
3280
Advantage
56
Shanghai YouPeng Chemical Co. Ltd.
Tel
021-69005955 13701776567
Fax
021-69005775
Email
youpengchem@163.com
Country
China
ProdList
4161
Advantage
56
Sichuan Hainuowei Technology Co. Ltd.
Tel
13708085536 13708085536
Fax
QQ : 121102042
Email
hanovichem@163.com
Country
China
ProdList
3282
Advantage
56
Sicemo Ltd.
Tel
0532-85625977 13668866880
Email
interchem@foxmail.com
Country
China
ProdList
74
Advantage
55
More
Less

View Lastest Price from 3-Acetylthiophene manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
3-Acetylthiophene 1468-83-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26
Shaanxi Dideu Medichem Co. Ltd
Product
3-Acetylthiophene 1468-83-3
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-22
Hebei Zhanyao Biotechnology Co. Ltd
Product
3-Acetylthiophene 1468-83-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 Tons
Release date
2021-10-13

1468-83-3, 3-AcetylthiopheneRelated Search:

Kresoxim-methyl Methyl salicylate METSULFURON METHYL 4,4'-Diacetylbiphenyl Methyl acetate Acetylferrocene Tribenuron methyl N-ACETYL-L-TYROSINE ETHYL ESTER Tetraacetylethylenediamine Thiophanate-methyl Methyl 3-Acetyl benz[b]thiophene 6,6-DIMETHYL-3-(METHYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBONITRILE 4-KETO-4,5,6,7-TETRAHYDROTHIANAPHTHENE 3-Acetyl-2,5-dimethylthiophene 2,5-Dichloro-3-acetylthiophene Methyl bromide alpha-acetylthiophen

  • 1-(Thien-3-yl)ethan-1-one, 1-Oxo-1-(thien-3-yl)ethane
  • 3-Acetylthioph
  • Ethanone,1-(3-thienyl)-
  • Ketone, methyl 3-thienyl
  • Ketone,methyl3-thienyl
  • Acetylthiophene,95%
  • Acetylthiophene,97%
  • 3-Acetylthiophene99%
  • 3-Acetyl
  • 1-(Thien-3-yl)ethan-1-one
  • 1-(thiophen-3-yl)ethan-1-one
  • 3-Acetylthiophene, 98% 10GR
  • 1-thien-3-ylethanone
  • 3-Thienyl (methyl) ketone
  • 3-Acetylthiophene,98%
  • 1-(1-methyl-2-pyrrolyl)ethanone
  • Methyl 3-thienyl ketone for synthesis
  • 1-(3-THIENYL)ETHANONE
  • 1-(3-Thienyl)-1-ethanone
  • 1-Thiophen-3-yl-ethanone
  • 3-Acetylthiophen
  • METHYL 3-THIENYL KETONE
  • 3-ACETYLTHIOPHENE
  • 3-Acetylthiophene &gt
  • Acetylthiophene
  • Acetylthio[hene
  • 3-Acetylthiophene ISO 9001：2015 REACH
  • 1468-83-3
  • C6H6OS
  • Building Blocks
  • Heterocyclic Building Blocks
  • Thiophenes
  • Building Blocks
  • C4 to C6
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Sulphur Derivatives
  • Thiophene&Benzothiophene
  • Heterocyclic Compounds
  • Thiophenes