ChemicalBook > CAS DataBase List > B-HT 920 DIHYDROCHLORIDE

B-HT 920 DIHYDROCHLORIDE

Product Name
B-HT 920 DIHYDROCHLORIDE
CAS No.
36085-73-1
Chemical Name
B-HT 920 DIHYDROCHLORIDE
Synonyms
b-ht920;4H-Thiazolo[4;B-HT 920 2HCl;Talipexole HCl;Talipexole 2HCl;5-d]azepin-2-aMine;hydrochloride (1:2);Hydrochloric talipexole;talipexole hydrochloride;B-HT 920 (hydrochloride)
CBNumber
CB4437406
Molecular Formula
C10H17Cl2N3S
Formula Weight
282.23
MOL File
36085-73-1.mol
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B-HT 920 DIHYDROCHLORIDE Property

Melting point:
245°C dec.
storage temp. 
Desiccate at RT
solubility 
H2O: >20 mg/mL
form 
solid
color 
off-white
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
RTECS 
XJ7050340
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14177
Product name
B-HT 920 (hydrochloride)
Purity
≥95%
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
14177
Product name
B-HT 920 (hydrochloride)
Purity
≥95%
Packaging
10mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
14177
Product name
B-HT 920 (hydrochloride)
Purity
≥95%
Packaging
50mg
Price
$502
Updated
2024/03/01
Tocris
Product number
2759
Product name
B-HT920
Purity
≥98%(HPLC)
Packaging
50
Price
$523
Updated
2021/12/16
Tocris
Product number
2759
Product name
B-HT920
Purity
≥98%(HPLC)
Packaging
10
Price
$142
Updated
2021/12/16
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B-HT 920 DIHYDROCHLORIDE Chemical Properties,Usage,Production

Description

B-HT 920 is a potent agonist of dopamine 2 (D2) receptors (Ki = 5.8 nM) that shows selectivity for D2 over D3 and D4 receptors. It has neuroprotective and regenerative effects in animal models of Parkinson’s disease. B-HT 920 is also an agonist of α2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3; Ki = 0.35 μM) receptors.

Chemical Properties

B-HT 920 DIHYDROCHLORIDE is Light Yellow Solid

Uses

B-HT 920 DIHYDROCHLORIDE is an alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent

Definition

ChEBI: Talipexole dihydrochloride is an azepine.

Biological Activity

Dopamine D 2 receptor agonist, α 2 -adrenoceptor agonist and 5-HT 3 receptor antagonist. Displays antiParkinsonian activity.

B-HT 920 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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B-HT 920 DIHYDROCHLORIDE Suppliers

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36085-73-1, B-HT 920 DIHYDROCHLORIDERelated Search:

Levofloxacin HCL Capsule Levofloxacin hydrochloride Naloxone hydrochloride Olopatadine hydrochloride Donepezil Hydrochloride Trimetazidine dihydrochloride TALIPEXOLE

  • 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amineDihydrochloride,6-Allyl-2-amino-5,6,7,8-tetrahydro-4
  • B-HT920dihydrochlorideTalipexole
  • 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride
  • Talipexole, 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride
  • 5,6,7,8-Tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d] azepin-2-amine dihydrochloride
  • talipexole hydrochloride
  • 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride
  • 2-Amino-6-allyl-4,5,7,8-tetrahydro-6H-thiazolo(5,4-D)azepin-dihydrochlorid [german]
  • 4H-Thiazolo(4,5-D)azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propenyl)-, dihydrochloride
  • 4H-Thiazolo[4
  • 5-d]azepin-2-aMine
  • 8-tetrahydro-6-(2-propen-1-yl)-
  • hydrochloride (1:2)
  • Talipexole dihydrochloride(B-HT 920)
  • B-HT 920 2HCl
  • Hydrochloric talipexole
  • B-HT 920 (hydrochloride)
  • TALIPEXOLE DIDHYDROCHLORIDE
  • 2-amino-6-allyl-4,5,7,8-tetrahydro-6h-thiazolo(5,4-d)azepin-dihydrochlorid
  • 5,6,7,8-tetrahydro-6-(2-propenyl)-4h-thiazolo(4,5-d)azepin-2-aminedihydrochl
  • 5-d)azepin-2-amine,5,6,7,8-tetrahydro-6-(2-propenyl)-4h-thiazolo(dihydroch
  • b-ht920
  • talipexoledihydrochloride
  • 6-ALLYL-2-AMINO-5,6,7,8-TETRAHYDRO-4H-THIAZOLO[4,5-D]AZEPINE DIHYDROCHLORIDE
  • 5,6,7,8-TETRAHYDRO-6-(2-PROPENYL)-4H-THIAZOLO[4,5-D]AZEPIN-2-AMINE DIHYDROCHLORIDE
  • 5,6,7,8-TETRAHYDRO-6-(2-PROPENYL)-4H-THIAZOLO[4,5-D]AZEPINE-2-AMINE DIHYDROCHLORIDE
  • B-HT 920 DIHYDROCHLORIDE
  • B-HT 920 DIHYDROCHLORIDE A2 ADRENOCEPTOR AGONI
  • B-HT 920 Dihydrochloride\nTalipexole
  • Talipexole HCl
  • 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine dihydrochloride
  • 6-Allyl-5,6,7,8-tetrahydro-4H-thiazole [4,5-d] aza-2-amine dihydrochloride
  • 4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-, hydrochloride (1:2)
  • Talipexole 2HCl
  • Talipexole dihydrochloride, 10 mM in DMSO
  • 36085-73-1
  • C10H17Cl2N3S
  • C10H15N3S2HCl
  • Adrenoceptor
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  • Inhibitors
  • Intermediates & Fine Chemicals
  • Neurochemicals
  • Pharmaceuticals