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REVEROMYCIN A

Product Name
REVEROMYCIN A
CAS No.
134615-37-5
Chemical Name
REVEROMYCIN A
Synonyms
REVEROMYCIN A;ZESGNAJSBDILTB-OXVOKJAASA-N;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
CBNumber
CB4443481
Molecular Formula
C36H52O11
Formula Weight
660.79
MOL File
134615-37-5.mol
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REVEROMYCIN A Property

Boiling point:
849.0±65.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF: soluble
form 
solid
pka
4.36±0.17(Predicted)
color 
tan
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R0654
Product name
Reveromycin A
Purity
solid
Packaging
100μg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
17458
Product name
Reveromycin A
Purity
≥99%
Packaging
250μg
Price
$353
Updated
2024/03/01
Cayman Chemical
Product number
17458
Product name
Reveromycin A
Purity
≥99%
Packaging
1mg
Price
$704
Updated
2024/03/01
TRC
Product number
R279910
Product name
Reveromycin A
Packaging
250μg
Price
$305
Updated
2021/12/16
Usbiological
Product number
464650
Product name
Reveromycin A
Packaging
100μg
Price
$453
Updated
2021/12/16
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REVEROMYCIN A Chemical Properties,Usage,Production

Uses

Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.

Uses

Reveromycin A is a spiroketal antibiotic inhibitor of EGF mitogenic activity. Inhibits the signal transduction of the epidermal growth factor. May be used

REVEROMYCIN A Preparation Products And Raw materials

Raw materials

Preparation Products

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REVEROMYCIN A Suppliers

Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58

134615-37-5, REVEROMYCIN ARelated Search:


  • REVEROMYCIN A
  • ZESGNAJSBDILTB-OXVOKJAASA-N
  • Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
  • 134615-37-5
  • C36H52O11
  • BioChemical
  • Antibiotics
  • Antibiotics A to Z
  • Antibiotics N-S
  • Epidermal Growth Factor Receptor (EGFR)Antibiotics
  • Interferes with Protein Synthesis
  • Antibiotics
  • Antibiotics A to
  • Antibiotics by Application
  • Antibiotics N-SAntibiotics
  • AntifungalAntibiotics
  • Mechanism of Action
  • Receptor Tyrosine Kinase Inhibitors
  • Spectrum of Activity
  • Antineoplastic and Immunosuppressive AntibioticsReceptor Tyrosine Kinase Biology