REVEROMYCIN A

Product Name: REVEROMYCIN A
CAS No.: 134615-37-5
Chemical Name: REVEROMYCIN A
Synonyms: REVEROMYCIN A;ZESGNAJSBDILTB-OXVOKJAASA-N;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
CBNumber: CB4443481
Molecular Formula: C36H52O11
Formula Weight: 660.79
MOL File: 134615-37-5.mol

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REVEROMYCIN A Property

Boiling point:: 849.0±65.0 °C(Predicted)
Density: 1.21±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMF: soluble
form: solid
pka: 4.36±0.17(Predicted)
color: tan

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R0654
Product name: Reveromycin A
Purity: solid
Packaging: 100μg
Price: $341
Updated: 2024/03/01

Cayman Chemical

Product number: 17458
Product name: Reveromycin A
Purity: ≥99%
Packaging: 250μg
Price: $353
Updated: 2024/03/01

Cayman Chemical

Product number: 17458
Product name: Reveromycin A
Purity: ≥99%
Packaging: 1mg
Price: $704
Updated: 2024/03/01

TRC

Product number: R279910
Product name: Reveromycin A
Packaging: 250μg
Price: $305
Updated: 2021/12/16

Usbiological

Product number: 464650
Product name: Reveromycin A
Packaging: 100μg
Price: $453
Updated: 2021/12/16

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REVEROMYCIN A Chemical Properties,Usage,Production

Uses

Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.

Uses

Reveromycin A is a spiroketal antibiotic inhibitor of EGF mitogenic activity. Inhibits the signal transduction of the epidermal growth factor. May be used

REVEROMYCIN A Preparation Products And Raw materials

Raw materials

Preparation Products

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REVEROMYCIN A Suppliers

China 41 India 1 Switzerland 1 United Kingdom 4 United States 11 Global 58

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
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Alfa Chemistry

Tel: 1-516-6625404
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Country: United States
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
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Lynnchem

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Email: info@lynnchem.com
Country: China
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Novachemistry

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Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
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Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
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BOC Sciences

Tel: +16314854226
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Country: United States
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Alfa Chemistry

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Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
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134615-37-5, REVEROMYCIN ARelated Search:

L-MIMOSINE VERRUCULOGEN Vinblastine sulfate S-Trityl-L-cysteine Morin hydrate Tangeretin MALVIDIN CHLORIDE TRYPROSTATIN A (E,E)-2,4-Dodecadienal FEMA 3766 1,1-DI(2-METHYLBUTOXY)ETHANE REVEROMYCIN A ACETIC ACID 2-METHYL-4-PENTEN-2-YL ESTER REVEROMYCIN D REVEROMYCIN C REVEROMYCIN B (-)-Reveromycin B, Synthetic (-)-REVEROMYCIN B

REVEROMYCIN A

ZESGNAJSBDILTB-OXVOKJAASA-N

Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester

134615-37-5

C36H52O11

BioChemical

Antibiotics

Antibiotics A to Z

Antibiotics N-S

Epidermal Growth Factor Receptor (EGFR)Antibiotics

Interferes with Protein Synthesis

Antibiotics

Antibiotics A to

Antibiotics by Application

Antibiotics N-SAntibiotics

AntifungalAntibiotics

Mechanism of Action

Receptor Tyrosine Kinase Inhibitors

Spectrum of Activity

Antineoplastic and Immunosuppressive AntibioticsReceptor Tyrosine Kinase Biology