ChemicalBook > CAS DataBase List > Doxifluridine

Doxifluridine

Product Name
Doxifluridine
CAS No.
3094-09-5
Chemical Name
Doxifluridine
Synonyms
flutron;5'-DFUR;5'DFURD;furtulon;AMC 0101;5-F-5‘-dU;RO-21-9738;5-cl-5'-dU;Doxifluidine;DOXIFLURIDINE
CBNumber
CB4461786
Molecular Formula
C9H11FN2O5
Formula Weight
246.19
MOL File
3094-09-5.mol
More
Less

Doxifluridine Property

Melting point:
188-192 °C(lit.)
alpha 
D25 +18.4° (c = 0.419 in water)
Density 
1.3751 (estimate)
refractive index 
20 ° (C=1, H2O)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
7.4(at 25℃)
color 
White
Merck 
14,3437
CAS DataBase Reference
3094-09-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
2
RTECS 
YU7526000
Hazard Note 
Irritant
HazardClass 
IRRITANT, IRRITANT-HARMFUL
HS Code 
29349990
Toxicity
LD50 (14 day) in mice or rats (mg/kg): >1000 i.v.: >2000 s.c.; in male, female mice, male, female rats (mg/kg): >5000, >5000, 3471, 3390 orally (Shimizu)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F8791
Product name
5-Fluoro-5′-deoxyuridine
Packaging
25MG
Price
$86.6
Updated
2023/06/20
Sigma-Aldrich
Product number
Y0001644
Product name
Capecitabine impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
Y0001644
Price
$218
Updated
2023/06/20
Sigma-Aldrich
Product number
F8791
Product name
5-Fluoro-5′-deoxyuridine
Packaging
100MG
Price
$267
Updated
2023/06/20
Sigma-Aldrich
Product number
F8791
Product name
5-Fluoro-5′-deoxyuridine
Packaging
250MG
Price
$466
Updated
2023/06/20
Sigma-Aldrich
Product number
PHR2850
Product name
5′-deoxy-5-fluorouridine
Purity
certified reference material, pharmaceutical secondary standard
Packaging
50MG
Price
$452
Updated
2022/05/15
More
Less

Doxifluridine Chemical Properties,Usage,Production

Description

Doxifluridine is a prodrug derivative of 5-fluorouracil (5-FU). As an antineoplastic it is more potent than 5-FU in the treatment of breast, stomach, colon and rectal cancers.

Chemical Properties

White Solid

Originator

Hoffmann-LaRoche (USA)

Uses

A prodrug of 5-Flurouridine. A fluorinated pyrimidine nucleoside with cytostatic activity

Uses

An antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes. A metabolite of Capecitabine

Uses

antineoplastic, pyrimidine antimetabolite

Uses

5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.

Definition

ChEBI: A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluoro racil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.

brand name

Furtulon

Biochem/physiol Actions

Doxifluridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts transformed by H-ras or trk oncogenes. Possesses anticachectic activity which is independent of its antiproliferative activity.

Doxifluridine Preparation Products And Raw materials

Raw materials

Palladium carbon fine chemical catalyzer p-Toluenesulfonic acid monohydrate Ethyl acetate Triphenylantimony Iodomethane 2,2-Dimethoxypropane

Preparation Products

More
Less

Doxifluridine Suppliers

Americas 1 Canada 1 China 271 China Hong Kong 2 Europe 3 Germany 3 India 7 Italy 1 Japan 4 South Korea 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 14 United States 45 Global 356
Suzhou Tianhong Medicine Chemical Technology Co.,Ltd.
Tel
18949937116
Email
dongye.huaxue@126.com
Country
China
ProdList
145
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8838
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9462
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1972
Advantage
58
Nanjing ShengSai Chemical Co., Ltd.
Tel
025-85205967 13951876367
Fax
025-85205967
Email
shengsaichem@163.com
Country
China
ProdList
811
Advantage
58
Wuhan DKY Technology Co.,Ltd.
Tel
27-81302488 18007166089
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
2024
Advantage
58
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9346
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Modachem Shanghai Co., Ltd
Tel
+86 (0)21 51320687 51371369 1744605818
Fax
+86 (0)21 51371369
Country
China
ProdList
1578
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4943
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10276
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Dongyang Honsen Co., Limited
Tel
+86-0579-86846643 18072368515
Fax
+86-0579-86846643
Email
sales@honsentech.com.cn
Country
China
ProdList
124
Advantage
55
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Watson Biotechnology Co.,Ltd
Tel
027-59207879 1972026995 18140587686
Fax
QQ：1972026995
Email
sales@3600chem.com
Country
China
ProdList
4666
Advantage
55
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7850
Advantage
55
Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6463
Advantage
55
More
Less

View Lastest Price from Doxifluridine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
5-Fluoro-5′-deoxyuridine 3094-09-5
Price
US $0.00/g
Min. Order
1g
Purity
≥98.0%
Supply Ability
10kg/month
Release date
2021-09-28
Shaanxi Dideu Medichem Co. Ltd
Product
Doxifluridine 3094-09-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-05
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Doxifluridine 3094-09-5
Price
US $19.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100tons
Release date
2021-12-06

3094-09-5, DoxifluridineRelated Search:

5-Fluorouridine Chenodeoxycholic acid 1-beta-D-Arabinofuranosyluracil Ursodeoxycholic acid 5-Fluorouracil DL-PHENYLEPHRINE HYDROCHLORIDE Trifluridine Floxuridine 3'-O-(5'-Deoxy-α-D-ribofuranosyl) Capecitabine 5'-Deoxy-5-fluorocytidine 2'-O-(5'-Deoxy-β-D-ribofuranosyl) Capecitabine 5'-deoxy-5-fluore-N-[(pentoyloxy)carbonyl]cytidine 2',3'-diacetate CAPECITABINE related substance USP 5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine alpha-Capecitabine 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine 5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine uridine diphosphate glucose {= UDP-glucose}

  • 5’-deoxy-5-fluoro-uridin
  • Doxifluridine/5-Fluoro-5′-deoxyuridine
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-oxolan-2-yl]-5-fluoro-pyrimidine-2,4-dione
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-quinone
  • Capecitabine Related Compound B (20 mg) (5'-deoxy-5-fluorouridine)
  • 5μdFUrd, Doxifluridine
  • 5μdFUrd, 5-Fluoro-5μ-deoxyuridine
  • 5’-Deoxy-5-fluomuridine
  • 2,4(1H,3H)-Pyrimidinedione, 1-(5-deoxy-b-D-ribofuranosyl)-5-fluoro-
  • 5Urd, 5-Fluoro-5deoxyuridine
  • URIDINE,5''-DEOXY-5-FLUORO
  • 1-[(2s,3s,4r,5s)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl]-5-fluoropyrimidine-2,4(1h,3h)-dione
  • flutron
  • furtulon
  • Doxifluridine 3094-9-5
  • 1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
  • 5’dUrd, 5-Fluoro-5’-deoxyuridine, 5’-DFUR, Doxifluridine
  • 5'-dFUrd Doxifluridine 1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
  • Doxifluridine(Ro 21-9738)
  • CAPECITABINE related substance USP B
  • Capecitabine Impurity 16（Capecitabine EP Impurity B）
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-2-oxolanyl]-5-fluoropyrimidine-2,4-dione
  • RO-21-9738
  • (+)-5-FLUORO-5'-DEOXYURIDINE
  • 5-FLUORO-5'-DEOXYURIDINE
  • 5'-DEOXY-5-FLUOROURIDINE
  • 5'-DEOXYFLUOROURIDINE
  • 5'-DFUR
  • 5'DFURD
  • DOXIFLURIDINE
  • MURINE RECOMBINANT
  • Doxifluridine (furtulon)
  • DOXIFLUIRDINE
  • 5'-Deoxy-fluorouridine(DFUR)/Doxifluridine
  • (+)-5-FLUORO-5'-DEOXYURIDINE 97%
  • 5-FLURO-5’-DEOXYURIDINE
  • 5Deoxy-5-fluorouridine, 5DFUR, 5dFUrd, Ro-21-9738
  • Doxifluidine
  • DOXIFLURIDINE(SUBJECTTOPATENTFREE)
  • (+)-5-Fluoro-5'-deoxyuridine98%
  • 5-Fluorodesoxyuridine
  • Uridine, 5'-deoxy-5-fluoro- (8CI, 9CI)
  • 5-FLUORO-5''-DEOXYURIDINE / DOXIFLURIDINE / 5''-DEOXY-FLUOROURIDINE
  • (+)-Doxifluridine, (+)-1-(beta-D-5'-Deoxyribofuranosyl)-5-fluorouracil
  • 5-F-5‘-dU
  • 5'-DFUR-13C5 (5'-Deoxy-5-fluorouridine, Doxifluridine-13C5)
  • AMC 0101
  • 5-cl-5'-dU
  • Doxifluridine, >=98.5%
  • Capecitabine USP RC B
  • Doxifluridine Doxifluridine
  • Capecitabine Impurity B
  • 5'-Deoxy-5-fluorouridine&gt
  • Capecitabine EP Impurity B (5'-DFUR, Doxifluridine)
  • 5’-deoxy-5-fluorouridine, Doxifluridine 5'-DFUR
  • Doxifluridine USP/EP/BP
  • Capecitabine EP Impurity B/ Capecitabine Related Compund B (Doxifluridine/ Deoxy-5-fluorouridine)