N6-CYCLOHEXYLADENOSINE

Product Name: N6-CYCLOHEXYLADENOSINE
CAS No.: 36396-99-3
Chemical Name: N6-CYCLOHEXYLADENOSINE
Synonyms: CHA;Cyclohexyladenosine;N-Cyclohexyladenosine;N6-CYCLOHEXYLADENOSINE;Adenosine, N-cyclohexyl-;N6-Cyclohexyladenosine,CHA;N(sup 6)-cyclohexyladenosine;(2R,4S)-4-fluoropyrrolidine-6-carboxylicacid;N6-CYCLOHEXYLADENOSINE (CHA) SELECTIVE A 1 ADENOSIN;(2R,3R,4S,5R)-2-(6-(CyclohexylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
CBNumber: CB4468462
Molecular Formula: C16H23N5O4
Formula Weight: 349.38
MOL File: 36396-99-3.mol

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N6-CYCLOHEXYLADENOSINE Property

Melting point:: 182 - 184°C
Boiling point:: 675.2±65.0 °C(Predicted)
Density: 1.71±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
pka: 13.12±0.70(Predicted)
color: White to Off-White
Stability:: Hygroscopic

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Safety

WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28427
Product name: N6-Cyclohexyladenosine
Packaging: 50mg
Price: $96
Updated: 2024/03/01

Cayman Chemical

Product number: 28427
Product name: N6-Cyclohexyladenosine
Packaging: 100mg
Price: $180
Updated: 2024/03/01

Cayman Chemical

Product number: 28427
Product name: N6-Cyclohexyladenosine
Packaging: 25mg
Price: $62
Updated: 2024/03/01

Tocris

Product number: 6863
Product name: N6-Cyclohexyladenosine
Purity: ≥98%(HPLC)
Packaging: 50
Price: $85
Updated: 2021/12/16

TRC

Product number: C989785
Product name: N6-Cyclohexyladenosine
Packaging: 500mg
Price: $745
Updated: 2021/12/16

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N6-CYCLOHEXYLADENOSINE Chemical Properties,Usage,Production

Description

N⁶-Cyclohexyladenosine is an adenosine receptor agonist. It selectively binds to adenosine A₁ receptors in rat cortical membranes (IC₅₀ = 2.3 nM) over A₂ receptors in rat striatal membranes (IC₅₀ = 870 nM). N⁶-Cyclohexyladenosine decreases heart rate and increases coronary flow in a perfused working rat heart model ex vivo (EC₂₅s = 5 and 860 nM, respectively). In vivo, it decreases heart rate and blood pressure in normotensive rats (EC₂₅s = 2.4 and 4.2 μg/kg, respectively). N⁶-Cyclohexyladenosine (100 μM) induces sleep in rats when administered via basal forebrain infusion. N⁶-Cyclohexyladenosine also decreases locomotor activity in mice (ED₅₀ = 60 μg/kg, i.p.).

Uses

N6-Cyclohexyladenosine is a derivative of Adenosine (A280400), and is used testing adenosine A1 and A2A receptor activation for pharmaceuticals such as antidepressants. N6-Cyclohexyladenosine also is used as a JAK2 inhibitor, blocking STAT3 signalling in human cancer cells.

Biochem/physiol Actions

Selective A1 adenosine receptor agonist.

storage

Store at -20°C

N6-CYCLOHEXYLADENOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-CYCLOHEXYLADENOSINE Suppliers

China 40 Germany 1 India 1 Russia 1 Switzerland 1 United Kingdom 1 United States 11 Global 56

MedChemexpress LLC

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TargetMol Chemicals Inc.

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Aladdin Scientific

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MP Biomedicals, Inc.

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George Uhe Co., Inc.

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36396-99-3, N6-CYCLOHEXYLADENOSINERelated Search:

Tetramethylthiuram Disulfide Vulcanization accelerator 2',3'-dideoxy-N(6)-cyclohexyladenosine ferritin-cyclohexyladenosine N-ALLYL-N-CYCLOHEXYLADENOSINE N(6)-allyl-N(6)-cyclohexyladenosine (2S)-N6-[2-ENDO-NORBORNYL]ADENOSINE N6-METHYL-2'-DEOXY-ADENOSINE SDZWAG994 CYCLOHEXYLADENOSINE, N6-[ADENINE-2,8-3H]-,N 6-CYCLOHEXYLADENOSINE-[2,8-3H] 6-(METHYLAMINO)PURINE 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE 6-N-HEXYLAMINOPURINE N6-CYCLOHEXYLADENOSINE

CHA

N6-CYCLOHEXYLADENOSINE

N6-CYCLOHEXYLADENOSINE (CHA) SELECTIVE A 1 ADENOSIN

N(sup 6)-cyclohexyladenosine

Cyclohexyladenosine

N-Cyclohexyladenosine

Adenosine, N-cyclohexyl-

N6-Cyclohexyladenosine,CHA

(2R,3R,4S,5R)-2-(6-(CyclohexylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol

(2R,4S)-4-fluoropyrrolidine-6-carboxylicacid

N-6-Cyclohexyladenosine,inhibit,Inhibitor,N6Cyclohexyladenosine,Adenosine Receptor,N6-Cyclohexyladenosine,N6 Cyclohexyladenosine,P1 receptor

36396-99-3