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Pyrimethanil

Product Name
Pyrimethanil
CAS No.
53112-28-0
Chemical Name
Pyrimethanil
Synonyms
Pyrimethani;Mytho;SCALA;MYTHOS;Penbotec;Hsdb 6916;Dynmethanil;PYRIMETHANIL;Pyrimethanil 0;Pyrimethanil [iso]
CBNumber
CB4473703
Molecular Formula
C12H13N3
Formula Weight
199.25
MOL File
53112-28-0.mol
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Pyrimethanil Property

Melting point:
96°C
Boiling point:
362.8±45.0 °C(Predicted)
Density 
1.15
vapor pressure 
2.2 x l0-5 Pa (25 °C)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO: 130 mg/mL (652.45 mM)
form 
Solid
pka
3.52
color 
White to off-white
Water Solubility 
0.121 g/L (25 ºC)
BRN 
151589
InChI
InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)
InChIKey
ZLIBICFPKPWGIZ-UHFFFAOYSA-N
SMILES
C1(NC2=CC=CC=C2)=NC(C)=CC(C)=N1
CAS DataBase Reference
53112-28-0(CAS DataBase Reference)
EPA Substance Registry System
Pyrimethanil (53112-28-0)
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Safety

Hazard Codes 
N
Risk Statements 
51/53
Safety Statements 
60
RIDADR 
UN 3077
WGK Germany 
2
HS Code 
2933599590
Hazardous Substances Data
53112-28-0(Hazardous Substances Data)
Toxicity
LD50 (mg/kg): 4061-5358 orally in mice; 4150-5971 orally in rats; >5000 dermally in rats; LC50 (96 hr) in mirror carp, rainbow trout (mg/l): 35.36, 10.56 (Neumann)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
40947
Product name
Pyrimethanil
Purity
certified reference material, TraceCERT?
Packaging
50mg
Price
$185
Updated
2024/03/01
Sigma-Aldrich
Product number
31577
Product name
Pyrimethanil
Purity
PESTANAL
Packaging
250mg
Price
$136
Updated
2024/03/01
TRC
Product number
P997250
Product name
Pyrimethanil
Packaging
10g
Price
$1165
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
42138
Product name
Pyrimethanil
Packaging
10g
Price
$1460
Updated
2021/12/16
Matrix Scientific
Product number
074289
Product name
4,6-Dimethyl-N-phenyl-2-pyrimidinamine
Purity
95+%
Packaging
5g
Price
$151
Updated
2021/12/16
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Pyrimethanil Chemical Properties,Usage,Production

Chemical Properties

Pyrimethanil is a white to light yellow crystalline powder which is sparingly soluble in water but soluble in most organic solvents. Commercial product is available as a brown emulsifiable concentrate.

Uses

Pyrimethanil provides both protective and curative control of fungal diseases in pome fruits (leaf scab caused by Venturiu inaequalis), vines, fruits, vegetables and ornamentals (grey mould)

Uses

Pyrimethanil is a broad spectrum anilino-pyrimidine foliar fungicide. Pyrimethanil functions by inhibiting the biosynthesis of methionine in Botrytis cinerea.

Preparation

Pyrimethanil is produced by reaction of 2-bromo-4,6-dimethylpyrimidine with aniline.

Definition

ChEBI: Pyrimethanil is a member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6. A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control Botrytis cinerea throughout the winemaking process in grapes, must, fermenting must and wine. It has a role as an aryl hydrocarbon receptor agonist, an environmental contaminant, a xenobiotic and an antifungal agrochemical. It is an aminopyrimidine, a secondary amino compound and an anilinopyrimidine fungicide.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 30, p. 1942, 1982 DOI: 10.1248/cpb.30.1942

General Description

Pyrimethanil is an anilino-pyrimidine, broad spectrum fungicide primarily used for the control of gray mould and leaf scab on fruits, vegetables and ornamentals. Its mode of action involves inhibition of the secretion of hydrolytic enzymes by the fungi during the infection process, thus stopping the further development of the disease.

Agricultural Uses

Fungicide: Used on grapes, strawberries, tomatoes, onions, beans, cucumbers, eggplant, and ornamental.

Trade name

SCALA®; SN 100309®

Potential Exposure

A pyrimidine fungicide used on grapes, strawberries, tomatoes, onions, beans, cucumbers, eggplant, and ornamental plants.

Metabolic pathway

Limited data are available in the open literature. Information presented in this summary is abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1995). Hydroxylation at the methyl, phenyl or pyrimidine moiety is the primary metabolic pathway of pyrimethanil in soil, plants and animals. Cleavage of the aniho-pyrimidine linkage was observed as a minor metabolic reaction. The formation of nitro- analogues of pyrimethanil is a novel nitration reaction observed in the soil metabolism study (Scheme 1).

Shipping

UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Degradation

Pyrimethanil (1) is stable to hydrolytic degradation in the environmentally relevant pH range (5-9) at 22-50 °C.
Pyrimethanil degraded rapidly at pH 4 and 30 °C (DT50 1 day) when the sterile buffered solution was exposed to mercury arc lamp (200-500 nm). The DT50 of pyrimethanil in pH 7 solution under the same photolysis test conditions was ca.77 days. There is no information on the chemical nature of pyrimethanil aqueous photolysis products.

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explo- sions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste Disposal

Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. If this material cannot be disposed of according to label instruc- tions, it may be dissolved or mixed with a combustible sol- vent and burned in a chemical incinerator equipped with an afterburner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers.

Pyrimethanil Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyrimethanil Suppliers

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View Lastest Price from Pyrimethanil manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Pyrimethanil 53112-28-0
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-21
qingdao trust agri chemical co.,ltd
Product
Pyrimethanil 53112-28-0
Price
US $0.00/kg
Min. Order
100kg
Purity
10%
Supply Ability
20tons
Release date
2024-07-03
Hebei Mojin Biotechnology Co., Ltd
Product
Pyrimethanil 53112-28-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-20

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