BETAMETHASONE BENZOATE (200 MG)

Product Name: BETAMETHASONE BENZOATE (200 MG)
CAS No.: 22298-29-9
Chemical Name: BETAMETHASONE BENZOATE (200 MG)
Synonyms: W-5975;17-Benzoate;16-beta)-(11-beta;betamethasonebenzoate;Nintedanib Impurity 155;betamethasone17-benzoate;BETAMETHASONE BENZOATE (200 MG);Betamethasone Benzoate (1067307);BETAMETHASONE BENZOATE USP(CRM STANDARD);9-fluoro-11,21-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl benzoate
CBNumber: CB4501383
Molecular Formula: C35H41FO8
Formula Weight: 608.6936432
MOL File: 22298-29-9.mol

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BETAMETHASONE BENZOATE (200 MG) Property

Melting point:: 225-228°
alpha: D24 +63.5° (dioxane)
Boiling point:: 641.0±55.0 °C(Predicted)
Density: 1.1732 (estimate)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 12.93±0.70(Predicted)

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Safety

RIDADR: UN 2811 6.1 / PGII
WGK Germany: 1
HS Code: 2937220000
Toxicity: LD50 scu-rat: 194 mg/kg TXAPA9 8,250,66

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1067307
Product name: Betamethasone benzoate
Packaging: 200mg
Price: $413
Updated: 2025/07/31

TRC

Product number: B327995
Product name: Betamethasone17-Benzoate
Packaging: 50mg
Price: $140
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001695
Product name: BETAMETHASONE BENZOATE
Purity: 95.00%
Packaging: 5MG
Price: $497.72
Updated: 2021/12/16

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BETAMETHASONE BENZOATE (200 MG) Chemical Properties,Usage,Production

Originator

Benisone,Warner Lambert,US,1973

Uses

BETAMETHASONE BENZOATE (200 MG) is an analog of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.

Definition

ChEBI: Betamethasone benzoate is a 21-hydroxy steroid.

Manufacturing Process

A mixture of 50 g of betamethasone, 50 cc of dimethylformamide, 50 cc of methyl orthobenzoate and 1.5 g of p-toluenesulfonic acid is heated for 24 hours on oil bath at 105°C while a slow stream of nitrogen is passed through the mixture and the methanol produced as a byproduct of the reaction is distilled off. After addition of 2 cc of pyridine to neutralize the acid catalyst the solvent and the excess of methyl orthobenzoate are almost completely eliminated under vacuum at moderate temperature. The residue is chromatographed on a column of 1,500 g of neutral aluminum oxide. By elution with ether-petroleum ether 30 g of a crystalline mixture are obtained consisting of the epimeric mixture of 17α,21-methyl orthobenzoates. This mixture is dissolved without further purification, in 600 cc of methanol and 240 cc of methanol and 240 cc of aqueous 2N oxalic acid are added to the solution. The reaction mixture is heated at 40°-50°C on water bath, then concentrated under vacuum, The residue, crystallized from acetone-ether, gives betamethasone 17-benzoate, MP 225°-231°C.

brand name

Uticort (Parke- Davis).

Therapeutic Function

Glucocorticoid

Safety Profile

Poison by subcutaneous route.An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of F-.

BETAMETHASONE BENZOATE (200 MG) Preparation Products And Raw materials

Raw materials

Preparation Products

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BETAMETHASONE BENZOATE (200 MG) Suppliers

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22298-29-9, BETAMETHASONE BENZOATE (200 MG)Related Search:

Benzyl benzoate Potassium benzoate BETAMETHASONE BENZOATE (200 MG) Betamethasone Betamethasone 17,21-dipropionate Betamethasone 17-valerate BetaMethasone (hydrochloride) Beclomethasone dipropionate

BETAMETHASONE BENZOATE (200 MG)

16-beta)-(11-beta

betamethasone17-benzoate

betamethasonebenzoate

pregna-1,4-diene-3,20-dione,17-(benzoyloxy)-9-fluoro-11,21-dihydroxy-16-methyl

BETAMETHASONE BENZOATE USP(CRM STANDARD)

(17R)-16β-Methyl-17α-(benzoyloxy)-11β,21-dihydroxy-9α-fluoropregna-1,4-diene-3,20-dione

17-Benzoyloxy-9-fluoro-11β,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione

W-5975

17-Benzoate

Pregna-1,4-diene-3,20-dione, 17-(benzoyloxy)-9-fluoro-11,21-dihydroxy-16-methyl-, (11β,16β)-

(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] benzoate

Betamethasone 17-benzoateQ: What is Betamethasone 17-benzoate Q: What is the CAS Number of Betamethasone 17-benzoate Q: What is the storage condition of Betamethasone 17-benzoate Q: What are the applications of Betamethasone 17-benzoate

Betamethasone Benzoate (1067307)

Nintedanib Impurity 155

9-fluoro-11,21-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl benzoate

22298-29-9