GLYCIDYL NEODECANOATE, MIXTURE OF BRANCHED ISOMERS Property

Boiling point:

310.14°C (rough estimate)

Density 

0.966 g/mL at 25 °C(lit.)

vapor pressure 

1.5Pa at 24.85℃

refractive index 

n20/D 1.444(lit.)

Flash point:

113 °C

Water Solubility 

70mg/L at 20℃

Stability:

Stable. Combustible. Reacts vigorously with strong oxidizing agents, acids, curing agents.

LogP

4.4 at 20℃

EPA Substance Registry System

Glycidyl neodecanoate (26761-45-5)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RTECS 

QO7800000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H341Suspected of causing genetic defects

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

GLYCIDYL NEODECANOATE, MIXTURE OF BRANCHED ISOMERS Chemical Properties,Usage,Production

Chemical Properties

yellow liquid

Uses

This material may be used as an epoxy resin reactive diluent, as a component of epoxy coating systems, and as an ingredient in alkyl resins to modify film properties. Improved chemical resistance, weatherability, film hardness, and acid number control are the properties enhanced in epoxy resin applications by the use of this material.

Production Methods

The glycidyl ester of neodecanoic acid (NAGE) is produced by the reaction of neodecanoic acid with epichlorohydrin in the presence of base.

General Description

Clear yellow liquid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

GLYCIDYL NEODECANOATE, MIXTURE OF BRANCHED ISOMERS reacts vigorously with strong oxidizing agents and strong Lewis and mineral acids. Reacts with considerable heat release with many curing agents.

Fire Hazard

GLYCIDYL NEODECANOATE, MIXTURE OF BRANCHED ISOMERS is probably combustible.

Carcinogenicity

The mutagenic activity of glycidyl ester of neodecanoic acid was investigated in cultures of S. typhimutium TA98, TA100, TA102, TA1535, TA1537, and TA1538; E. coli WP2 and WP2 uvr A; and in cultures of S. cerevisiae JD1, both with and without the incorporation of rat liver microsomal enzymes. The results indicated that glycidyl ester of neodecanoic acid induced an increase in mutation frequency only after metabolic activation in Salmonella strains TA100, TA1535, and TA1538. The mutation frequency was within the spontaneous frequency range in the absence of S9 fractions for these strains; however, in some experiments weak responses were observed in the absence of S9. In TA98, TA102, TA1537, and TA1538, there was no increase in mutation frequency either with or without S9. There was no increase in gene mutation and frequency in either of the E. coli strains with or without activation. Similarly, in Saccharomyces no changes in gene conversion frequency were reported. In general, no significant effects were detected below 100mg of material per plate, suggesting that the mutagenic activity was relatively weak. The bacterial results indicate thatmutagenicity was expressed by both base-pair substitution and frameshift mechanisms.
In other studies, monolayer slides of cultures of rat liver (RL1) cells were exposed to culture medium containing glycidyl ester of neodecanoic acid, and after 24 h incubation, the slides were processed for metaphase chromosome analysis . In the RL1 cells, NAGE induced a low frequency of chromatid aberrations at concentrations just below the cytotoxic dose (50 mg/mL).