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PIMARIC ACID

Product Name
PIMARIC ACID
CAS No.
127-27-5
Chemical Name
PIMARIC ACID
Synonyms
Pimaric;NSC 2956;PIMARIC ACID;Pimaric Acid (>DextropiMaric Acid;Δ8(14)-PiMaric Acid;Pimaric acid (PiMA);Pimaric Acid (> 75%);Hexazinone Impurity 27;8(14),15-PiMaradien-18-oic Acid
CBNumber
CB4506393
Molecular Formula
C20H30O2
Formula Weight
302.45
MOL File
127-27-5.mol
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PIMARIC ACID Property

Melting point:
217-219°
alpha 
D18 +74.7° (c = 0.4 in chloroform); D20 +87.3° (in chloroform)
Boiling point:
bp18 282°
Density 
1.0434 (rough estimate)
refractive index 
1.4800 (estimate)
storage temp. 
Store at -20°C
solubility 
DMSO: soluble,Water: soluble
pka
4.68±0.60(Predicted)
LogP
6.731 (est)
EPA Substance Registry System
Pimaric acid (127-27-5)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26062
Product name
Pimaric Acid
Packaging
500μg
Price
$68
Updated
2022/04/27
Cayman Chemical
Product number
26062
Product name
Pimaric Acid
Packaging
5mg
Price
$269
Updated
2022/04/27
Cayman Chemical
Product number
26062
Product name
Pimaric Acid
Packaging
1mg
Price
$122
Updated
2022/04/27
Usbiological
Product number
286933
Product name
Pimaric acid
Packaging
1mg
Price
$582
Updated
2021/12/16
TRC
Product number
P445100
Product name
PimaricAcid(>75%)
Packaging
10mg
Price
$1540
Updated
2021/12/16
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PIMARIC ACID Chemical Properties,Usage,Production

Description

Pimaric acid is a resin acid that has been found in A. cordata and various pines. It reduces mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-α-stimulated human aortic smooth muscle cells (HASMCs) in a concentration-dependent manner when used at concentrations ranging from 5 to 20 μM. Pimaric acid (10-20 μM) reduces nuclear expression and binding of the transcription factors NF-κB and AP-1 to the MMP-9 promoter in HASMCs. Pimaric acid also reduces TNF-α-induced HASMC migration to control levels when used at a concentration of 20 μg/ml.

Uses

A novel activators of large-conductance Ca2+-activated K+ channel α-subunit.

Definition

ChEBI: (+)-Pimaric acid is a diterpenoid.

PIMARIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PIMARIC ACID manufacturers

Career Henan Chemical Co
Product
PIMARIC ACID 127-27-5
Price
US $1.00/KG
Min. Order
1KG
Purity
85.0-99.8%
Supply Ability
20 tons
Release date
2019-12-25

127-27-5, PIMARIC ACIDRelated Search:

Sodium tungstate 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one alpha-Cyperone beta-Sitosterol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether MOSLOFLAVONE Hydroxyecdysone beta-Eudesmol hydroxygenkwanin alpha-Terpineol cis-1,2,3,6-Tetrahydrophthalic anhydride sandaracopimaric acid PIMARIC ACID (CIS)-8-METHYLNON-6-ENOIC ACID

  • (1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-triMethyl-1-phenanthrenecarboxylic Acid
  • 13α-Methyl-13-vinylpodocarp-8(14)-en-15-oic acid
  • PIMARIC ACID
  • 1-phenanthrenecarboxylicacid,7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahyd
  • 7-trimethyl-,[1theta-(1alpha,4abeta,4balpha,7beta,10aalpha)]-ro-4a
  • 13-alpha-methyl-13-vinylpodocarp-8(14)-en-15-oic acid
  • 1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,4bS,7S,10aR)-
  • 8(14),15-PiMaradien-18-oic Acid
  • DextropiMaric Acid
  • NSC 2956
  • PiMara-8(14),15-dien-19-oic Acid
  • Δ8(14)-PiMaric Acid
  • Pimaric Acid (Contains 10-25% Sandaracopimaric Acid)
  • Pimaric Acid (&gt
  • Pimaric Acid (> 75%)
  • Pimaric
  • Hexazinone Impurity 27
  • Pimaric acid (PiMA)
  • 127-27-5
  • Activators
  • Aliphatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals