UNCARINE E

ChemicalBook > CAS DataBase List > UNCARINE E

Product Name: UNCARINE E
CAS No.: 5171-37-9
Chemical Name: UNCARINE E
Synonyms: UNCARINE E;Uncarine E-RM;ISOPTEROPODINE;7-Isopteropodine;Rhynchophylline E;allo-Isopteropodine;Isopteropodine (20 mg);Uncarine E,Isopteropodine;Isopteropodine(Uncarine E);(7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
CBNumber: CB4676247
Molecular Formula: C21H24N2O4
Formula Weight: 368.43
MOL File: 5171-37-9.mol

Less

UNCARINE E Property

Melting point:: 209-211 °C
Boiling point:: 555.2±50.0 °C(Predicted)
Density: 1.33
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 13.56±0.60(Predicted)
form: Solid
color: Pale Yellow to Pale Beige

Less

Safety

HS Code: 2939800000

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89816
Product name: Uncarine E
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $584
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1351107
Product name: Isopteropodine
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 20MG
Price: $1070
Updated: 2024/03/01

TRC

Product number: I874220
Product name: Isopteropodine
Packaging: 25mg
Price: $730
Updated: 2021/12/16

TRC

Product number: I874220
Product name: Isopteropodine
Packaging: 10mg
Price: $305
Updated: 2021/12/16

ChemScene

Product number: CS-0032252
Product name: Isopteropodine
Packaging: 5mg
Price: $343
Updated: 2021/12/16

Less

UNCARINE E Chemical Properties,Usage,Production

Description

This alkaloid occurs in several species of Uncaria and yields colourless crystals from MeOH. It is laevorotatory with [α]_D - 96° (CHCI3). The structure has been determined by spectroscopic methods.

Uses

Isopteropodine is an alkaloid extract from Uncaria Tomentosathat is believed to possess antiproliferative and pro-apoptotic effects.

Definition

ChEBI: Uncarine E is a member of indolizines.

References

Hart, Johns, Lamberton., Chem. Commun., 87 (1967)
Hemingway, Phillipson., 1. Pharm. Pharmacol., 24, 169P (1972)

UNCARINE E Preparation Products And Raw materials

Raw materials

Preparation Products

Less

UNCARINE E Suppliers

China 66 India 1 United Kingdom 3 United States 10 Global 80

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19172
Advantage: 64

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Biyu Biotechnology (Shanghai) Co., ltd

Tel: 021-26018599
Country: China
ProdList: 270
Advantage: 56

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973186 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 18338
Advantage: 68

Shanghai Uteam Biotechnology Co., Ltd.

Tel: 021-36031160 13311776681
Email: 3338195766@QQ.com
Country: China
ProdList: 5175
Advantage: 55

Shanghai Biological Technology Development Co., Ltd.

Tel: 021-69955236-807 13918189704
Fax: 021-65211385
Email: chinaruji@chinaruji.com
Country: China
ProdList: 5176
Advantage: 55

Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-85370565-229 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 8899
Advantage: 60

Chengdu Greenpure Biopharma CO.,Ltd

Tel: 028-88203606; 18283602253
Email: jancyzheng@gcgreenpure.com
Country: China
ProdList: 1589
Advantage: 58

Shanghai Standard Technology Co.,Ltd.

Tel: 021-021-57127007-6622-6622 15618937986
Fax: +86 (21) 5132-0077
Email: zhaok@nature-standard.com
Country: China
ProdList: 3016
Advantage: 58

Shanghai Innovative Reseach Center Of Traditional

Tel: 86-21-50801717-301
Fax: 86-21-50800509
Email: wangjh@sirc-tcm.sh.cn
Country: China
ProdList: 2070
Advantage: 58

Henan Alfachem Co.,Ltd.

Tel: 0371-0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9881
Advantage: 58

Jinan Feiteng Pharmaceutical Technology Co., Ltd.

Tel: 15589964716
Fax: qq：3360232875
Email: 15253102672@163.com
Country: China
ProdList: 211
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57412
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

Aktin Chemicals, Inc.

Tel: 028-85159085
Fax: 86-28-85159085 Ex:604
Email: info@aktinchem.com
Country: CHINA
ProdList: 1025
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30240
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5176
Advantage: 58

Shaanxi Pioneer Biotech Co., Ltd .

Tel: +8613259417953
Fax: 029-84385017
Email: sales@pioneerbiotech.com
Country: China
ProdList: 3000
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-29-87569266 15319487004
Fax: 029-88380327
Email: 1015@dideu.com
Country: China
ProdList: 4084
Advantage: 58

Chengdu Jiuding Chemical Technology Co., Ltd. - Song Bo

Tel: 18584079237
Email: 312074905@qq.com
Country: China
ProdList: 2505
Advantage: 58

Shanghai Bohu Biotechnology Co., LTD

Tel: 021-57763112 13585886131
Email: 3004987436@qq.com
Country: China
ProdList: 9693
Advantage: 58

Shanghai Hewu Biotechnology Co., LTD

Tel: 021-57886085 17317861055
Email: shhebio@126.com
Country: CHINA
ProdList: 7974
Advantage: 58

Aktin Chemicals, Inc.

Tel: 028-85159085
Email: info@aktinchem.com
Country: China
ProdList: 1769
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Nanjing Bencao Yikang Biotechnology Co., Ltd

Tel: +86-025-69790911 18362932668
Email: 522593521@qq.com
Country: China
ProdList: 1163
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

Foshan Treasure Biotechnology Co., Ltd

Tel: 0757-85921206 18520245316
Email: 2329783215@qq.com
Country: China
ProdList: 12661
Advantage: 58

Chengdu Push Bio-Technology Co., Ltd.

Tel: 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 9209
Advantage: 58

Shanghai Moqi Biological Technology Co., LTD

Tel: 021-38218169 13341702378
Email: 190129269@qq.com
Country: China
ProdList: 9126
Advantage: 58

Naturewill Biotechnology Co., Ltd.

Tel: 18113192475 18113192475
Email: 3157321941@qq.com
Country: China
ProdList: 5001
Advantage: 58

Chengdu RefMedic Biotech Co Ltd

Tel: 028-82253651 18140204969
Email: sales@refmedic.com
Country: China
ProdList: 2260
Advantage: 58

Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd

Tel: 18162595016; 18162595016
Email: 3287908757@qq.com
Country: China
ProdList: 9122
Advantage: 58

Shanghai Yanchun Biopharmaceutical Technology Co., Ltd

Tel: 4001-009266 17349750668
Email: product@sci-e.com
Country: China
ProdList: 2808
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: +86-18521732826
Email: market@aladdin-e.com
Country: China
ProdList: 48461
Advantage: 58

Wuhan Huangzhen Biochemical Co., Ltd

Tel: 13795480948 13795480948
Email: 3450865996@qq.com
Country: China
ProdList: 4958
Advantage: 58

SHANGHAI ZZBIO CO., LTD.

Tel: 15102117276 19921389125
Email: tech@zzbioco.com
Country: China
ProdList: 12065
Advantage: 58

RENI Pharmaceutical Technology Co., Ltd

Tel: 028-87865381 18108190480
Email: 2881944542@qq.com
Country: China
ProdList: 3302
Advantage: 58

Mensura Group Limited

Tel: 18109034517
Fax: 028-87362290
Email: 18109034517@163.com
Country: China
ProdList: 2898
Advantage: 58

Tel: 58896805
Email: 7993601name@qq.com
Country: CHINA
ProdList: 15092
Advantage: 58

Chengdu Greenpure Biopharma CO.,Ltd

Tel: 18283602253; +8618283602253
Email: jancyzheng@gcgreenpure.com
Country: China
ProdList: 953
Advantage: 58

Chengdu GLP biotechnology Co Ltd

Tel: 028-87075086 13350802083
Email: scglp@glp-china.com
Country: CHINA
ProdList: 1824
Advantage: 58

Shanghai Zheyan Biotech Co., Ltd.

Tel: 18017610038
Email: zheyansh@163.com
Country: CHINA
ProdList: 3619
Advantage: 58

Mensura Group Limited

Tel: +8618109034517
Fax: 028-87362290
Email: hkd008@vacorda.com
Country: China
ProdList: 2900
Advantage: 58

Chengdu Biopurify Phytochemicals Ltd.

Tel: +8618080483897
Email: sales@biopurify.com
Country: China
ProdList: 3772
Advantage: 58

5171-37-9, UNCARINE ERelated Search:

UNCARINE D(P) UNCARINE C SNAP-N-SHOOT 0.1mg/mL(P),UNCARINE C(P) alpha-Phenylpiperidine-2-acetamide UNCARINE E CHEMBRDG-BB 4002906 2-METHYL-3-PYRROLIDIN-1-YL-PROPAN-1-OL 1-(3-METHOXYPROPYL)-3-PYRROLIDINYL]METHANAMINE 3-AMINOMETHYL-1,3-DIHYDRO-INDOL-2-ONE CHEMBRDG-BB 4002903 UNCARINE C uncarine A Uncarine F UNCARINE D UNCARINE D SNAP-N-SHOOT 0.1mg/mL(P) UNCARINE E(P),UNCARINE E SNAP-N-SHOOT 0.1mg/mL(P) UNCARINE C SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD) Uncarine B UNCARINE D SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD)

allo-Isopteropodine

UNCARINE E

(7alpha,19alpha,20alpha)-19-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester

ISOPTEROPODINE

(7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester

7-Isopteropodine

(1R,4aR,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester

methyl (1R,4aR,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate

methyl (1R,4aR,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate

Isopteropodine (20 mg)

Isopteropodine(Uncarine E)

Rhynchophylline E

Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aS)-

(1'S,3S,4a'S,5a'S,10a'S)-methyl 1'-methyl-2-oxo-1',4a',5',5a',7',8',10',10a'-octahydrospiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate

Uncarine E,Isopteropodine

(1'S,3S,4a'S,5a'S,10a'S)-Methyl 1'-methyl-2-oxo-1',4a',5',5a',7',8',10',10a'-octahydrospiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate

Uncarine E-RM

5171-37-9

standard material,plant extracts