ChemicalBook > CAS DataBase List > UNCARINE E

UNCARINE E

Product Name
UNCARINE E
CAS No.
5171-37-9
Chemical Name
UNCARINE E
Synonyms
UNCARINE E;ISOPTEROPODINE;7-Isopteropodine;Rhynchophylline E;allo-Isopteropodine;Isopteropodine (20 mg);Uncarine E,Isopteropodine;Isopteropodine(Uncarine E);(7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester;(7alpha,19alpha,20alpha)-19-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
CBNumber
CB4676247
Molecular Formula
C21H24N2O4
Formula Weight
368.43
MOL File
5171-37-9.mol
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UNCARINE E Property

Melting point:
209-211 °C
Boiling point:
555.2±50.0 °C(Predicted)
Density 
1.33
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
13.56±0.60(Predicted)
form 
Solid
color 
Pale Yellow to Pale Beige
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Safety

HS Code 
2939800000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89816
Product name
Uncarine E
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$584
Updated
2024/03/01
Sigma-Aldrich
Product number
1351107
Product name
Isopteropodine
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
20MG
Price
$1070
Updated
2024/03/01
TRC
Product number
I874220
Product name
Isopteropodine
Packaging
25mg
Price
$730
Updated
2021/12/16
TRC
Product number
I874220
Product name
Isopteropodine
Packaging
10mg
Price
$305
Updated
2021/12/16
ChemScene
Product number
CS-0032252
Product name
Isopteropodine
Packaging
5mg
Price
$343
Updated
2021/12/16
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UNCARINE E Chemical Properties,Usage,Production

Description

This alkaloid occurs in several species of Uncaria and yields colourless crystals from MeOH. It is laevorotatory with [α]D - 96° (CHCI3). The structure has been determined by spectroscopic methods.

Uses

Isopteropodine is an alkaloid extract from Uncaria Tomentosathat is believed to possess antiproliferative and pro-apoptotic effects.

Definition

ChEBI: Uncarine E is a member of indolizines.

References

Hart, Johns, Lamberton., Chem. Commun., 87 (1967)
Hemingway, Phillipson., 1. Pharm. Pharmacol., 24, 169P (1972)

UNCARINE E Preparation Products And Raw materials

Raw materials

Preparation Products

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5171-37-9, UNCARINE ERelated Search:

UNCARINE D(P) UNCARINE C SNAP-N-SHOOT 0.1mg/mL(P),UNCARINE C(P) alpha-Phenylpiperidine-2-acetamide UNCARINE E CHEMBRDG-BB 4002906 2-METHYL-3-PYRROLIDIN-1-YL-PROPAN-1-OL 1-(3-METHOXYPROPYL)-3-PYRROLIDINYL]METHANAMINE 3-AMINOMETHYL-1,3-DIHYDRO-INDOL-2-ONE CHEMBRDG-BB 4002903 UNCARINE C uncarine A Uncarine F UNCARINE D UNCARINE D SNAP-N-SHOOT 0.1mg/mL(P) UNCARINE E(P),UNCARINE E SNAP-N-SHOOT 0.1mg/mL(P) UNCARINE C SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD) Uncarine B UNCARINE D SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD)

  • allo-Isopteropodine
  • UNCARINE E
  • (7alpha,19alpha,20alpha)-19-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
  • ISOPTEROPODINE
  • (7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
  • 7-Isopteropodine
  • (1R,4aR,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester
  • methyl (1R,4aR,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
  • methyl (1R,4aR,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
  • Isopteropodine (20 mg)
  • Isopteropodine(Uncarine E)
  • Rhynchophylline E
  • Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aS)-
  • (1'S,3S,4a'S,5a'S,10a'S)-methyl 1'-methyl-2-oxo-1',4a',5',5a',7',8',10',10a'-octahydrospiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate
  • Uncarine E,Isopteropodine
  • 5171-37-9
  • standard material,plant extracts