UNCARINE E

Product Name: UNCARINE E
CAS No.: 5171-37-9
Chemical Name: UNCARINE E
Synonyms: UNCARINE E;Uncarine E-RM;ISOPTEROPODINE;7-Isopteropodine;Rhynchophylline E;allo-Isopteropodine;Isopteropodine (20 mg);Uncarine E,Isopteropodine;Isopteropodine(Uncarine E);(7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
CBNumber: CB4676247
Molecular Formula: C21H24N2O4
Formula Weight: 368.43
MOL File: 5171-37-9.mol

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UNCARINE E Property

Melting point:: 209-211 °C
Boiling point:: 555.2±50.0 °C(Predicted)
Density: 1.33
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 13.56±0.60(Predicted)
form: Solid
color: Pale Yellow to Pale Beige

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Safety

HS Code: 2939800000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89816
Product name: Uncarine E
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $584
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1351107
Product name: Isopteropodine
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 20MG
Price: $1070
Updated: 2024/03/01

TRC

Product number: I874220
Product name: Isopteropodine
Packaging: 10mg
Price: $305
Updated: 2021/12/16

TRC

Product number: I874220
Product name: Isopteropodine
Packaging: 25mg
Price: $730
Updated: 2021/12/16

ChemScene

Product number: CS-0032252
Product name: Isopteropodine
Packaging: 5mg
Price: $343
Updated: 2021/12/16

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UNCARINE E Chemical Properties,Usage,Production

Description

This alkaloid occurs in several species of Uncaria and yields colourless crystals from MeOH. It is laevorotatory with [α]_D - 96° (CHCI3). The structure has been determined by spectroscopic methods.

Uses

Isopteropodine is an alkaloid extract from Uncaria Tomentosathat is believed to possess antiproliferative and pro-apoptotic effects.

Definition

ChEBI: Uncarine E is a member of indolizines.

References

Hart, Johns, Lamberton., Chem. Commun., 87 (1967)
Hemingway, Phillipson., 1. Pharm. Pharmacol., 24, 169P (1972)

UNCARINE E Preparation Products And Raw materials

Raw materials

Preparation Products

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UNCARINE E Suppliers

China 66 India 1 United Kingdom 3 United States 10 Global 80

J & K SCIENTIFIC LTD.

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Sinopharm Chemical Reagent Co,Ltd.

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5171-37-9, UNCARINE ERelated Search:

UNCARINE D(P) UNCARINE C SNAP-N-SHOOT 0.1mg/mL(P),UNCARINE C(P) alpha-Phenylpiperidine-2-acetamide UNCARINE E CHEMBRDG-BB 4002906 2-METHYL-3-PYRROLIDIN-1-YL-PROPAN-1-OL 1-(3-METHOXYPROPYL)-3-PYRROLIDINYL]METHANAMINE 3-AMINOMETHYL-1,3-DIHYDRO-INDOL-2-ONE CHEMBRDG-BB 4002903 UNCARINE C uncarine A Uncarine F UNCARINE D UNCARINE D SNAP-N-SHOOT 0.1mg/mL(P) UNCARINE E(P),UNCARINE E SNAP-N-SHOOT 0.1mg/mL(P) UNCARINE C SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD) Uncarine B UNCARINE D SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD)

allo-Isopteropodine

UNCARINE E

(7alpha,19alpha,20alpha)-19-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester

ISOPTEROPODINE

(7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester

7-Isopteropodine

(1R,4aR,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester

methyl (1R,4aR,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate

methyl (1R,4aR,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate

Isopteropodine (20 mg)

Isopteropodine(Uncarine E)

Rhynchophylline E

Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aS)-

(1'S,3S,4a'S,5a'S,10a'S)-methyl 1'-methyl-2-oxo-1',4a',5',5a',7',8',10',10a'-octahydrospiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate

Uncarine E,Isopteropodine

(1'S,3S,4a'S,5a'S,10a'S)-Methyl 1'-methyl-2-oxo-1',4a',5',5a',7',8',10',10a'-octahydrospiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate

Uncarine E-RM

5171-37-9

standard material,plant extracts