2-Chloromandelic acid
- Product Name
- 2-Chloromandelic acid
- CAS No.
- 10421-85-9
- Chemical Name
- 2-Chloromandelic acid
- Synonyms
- TIMTEC-BB SBB003705;2-Chloromandelic aci;2-CHLOROMANDELIC ACID;o-chloromandelic acid;Chloromandelic Acid DL-;DL- Chloromandelic acid;DL-2-CHLOROMANDELIC ACID;Orthochloromandelic acid;2-Chloromandelic acid,98%;RS-2-Chloro Mandelic acid
- CBNumber
- CB4680112
- Molecular Formula
- C8H7ClO3
- Formula Weight
- 186.59
- MOL File
- 10421-85-9.mol
2-Chloromandelic acid Property
- Melting point:
- 90-93 °C(lit.)
- Boiling point:
- 266.91°C (rough estimate)
- Density
- 1.3245 (rough estimate)
- refractive index
- 1.5250 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly, Sonicated), Methanol (Slightly)
- form
- Crystalline Powder
- pka
- 3.30±0.10(Predicted)
- color
- White to pale cream
- Water Solubility
- Very soluble in water.
- BRN
- 2367070
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C8H7ClO3/c9-6-4-2-1-3-5(6)7(10)8(11)12/h1-4,7,10H,(H,11,12)
- InChIKey
- RWOLDZZTBNYTMS-UHFFFAOYSA-N
- SMILES
- C(C1C=CC=CC=1Cl)(O)C(=O)O
- CAS DataBase Reference
- 10421-85-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- HS Code
- 29181990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 530182
- Product name
- 2-Chloromandelic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $163
- Updated
- 2025/07/31
- Product number
- C3937
- Product name
- 2-(2-Chlorophenyl)-2-hydroxyacetic Acid
- Purity
- min. 98.0 %
- Packaging
- 25G
- Price
- $72
- Updated
- 2025/07/31
- Product number
- C3937
- Product name
- 2-(2-Chlorophenyl)-2-hydroxyacetic Acid
- Purity
- min. 98.0 %
- Packaging
- 100G
- Price
- $180
- Updated
- 2025/07/31
- Product number
- C432673
- Product name
- 2-Chloromandelic acid
- Packaging
- 5g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C432673
- Product name
- 2-Chloromandelic acid
- Packaging
- 25g
- Price
- $55
- Updated
- 2021/12/16
2-Chloromandelic acid Chemical Properties,Usage,Production
Chemical Properties
White to pale cream crystalline powder
Uses
2-Chloromandelic acid, is used as a pharmaceutical intermediate as well as in the medicine industry. It is used as a intermediate of clopidrogrel.
General Description
2-Chloromandelic acid (2-ClMA) is a mandelic acid derivative. A report based on its solid state-NMR, X-ray powder diffraction (XPRD) and Fourier transform infrared spectroscopy (FTIR) data reveals that in solid state 2-ClMA exists as a racemic compound. The study also suggests that the crystals of racemic 2-ClMA belongs the monoclinic space group P21/c. The efficiency of (R)-(+)-N-benzyl-1-phenylethylamine in resolving racemate 2-ClMA has been investigated.
Synthesis
74-90-8
89-98-5
10421-85-9
52923-20-3
First, 150 mL of toluene was added to a flask equipped with a stirrer and an internal thermometer. Under stirring conditions, 0.09 g (0.08 x 10^-3 mol) of the (R,R)-VO salen complex from Example 1 and 21.1 g (0.15 mol) of freshly prepared 2-chlorobenzaldehyde were added sequentially. Subsequently, 10.1 g (0.375 mol) of hydrocyanic acid was added all at once. The resulting dark green homogeneous solution was stirred for 24 h at room temperature in a closed apparatus. The conversion was analyzed by gas chromatography (GC) to be 98% and the enantiomeric excess (ee) value of (S)-2-chloromandelate cyanohydrin was 73%.
References
[1] Patent: US2004/236129, 2004, A1. Location in patent: Page 4
[2] Patent: US2004/236129, 2004, A1. Location in patent: Page 4
[3] Patent: US2004/236129, 2004, A1. Location in patent: Page 4
[4] Patent: US2004/236129, 2004, A1. Location in patent: Page 4
[5] Patent: US2004/236129, 2004, A1. Location in patent: Page 4
2-Chloromandelic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloromandelic acid Suppliers
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- --
- Fax
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- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
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- Sales@kemikalieimport.dk
- Country
- Europe
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- Tel
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- info@camida.com
- Country
- Europe
- ProdList
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View Lastest Price from 2-Chloromandelic acid manufacturers
- Product
- 2-Chloromandelic acid 10421-85-9
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-26
- Product
- 2-Chloromandelic acid 10421-85-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-29
- Product
- 2-Chloromandelic acid 10421-85-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27