ChemicalBook > CAS DataBase List > 1-Indanone-6-carboxylic acid

1-Indanone-6-carboxylic acid

Product Name
1-Indanone-6-carboxylic acid
CAS No.
60031-08-5
Chemical Name
1-Indanone-6-carboxylic acid
Synonyms
6-CARBOXY-1-INDANONE;6-CARBOXYLIC ACID 1-INDANONE;1-INDANONE-6-CARBOXYLIC ACID;3-OXOINDANE-5-CARBOXYLIC ACID;3-OXO-INDAN-5-CARBOXYLIC ACID;3-oxo-1,2-dihydroindene-5-carboxylic Acid;2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID;3-oxo-2,3-dihydro-1H-indene-5-carboxylic acid;1H-Indene-5-carboxylic acid, 2,3-dihydro-3-oxo-;JR-8361, 2,3-Dihydro-3-oxo-1H-indene-5-carboxylic acid, 97%
CBNumber
CB4684307
Molecular Formula
C10H8O3
Formula Weight
176.17
MOL File
60031-08-5.mol
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1-Indanone-6-carboxylic acid Property

Melting point:
256-260 °C
Boiling point:
375.2±31.0 °C(Predicted)
Density 
1.381±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.99±0.20(Predicted)
Appearance
White to off-white Solid
CAS DataBase Reference
60031-08-5(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
25-36/37/38
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
Ⅲ
HS Code 
2918300090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
I655748
Product name
1-Indanone-6-carboxylicAcid
Packaging
25g
Price
$75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0967081
Product name
2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID
Purity
95.00%
Packaging
1G
Price
$1030.84
Updated
2021/12/16
AK Scientific
Product number
W7273
Product name
1-Indanone-6-carboxylicacid
Packaging
10g
Price
$1747
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0967081
Product name
2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID
Purity
95.00%
Packaging
5G
Price
$4244.63
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0967081
Product name
2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID
Purity
95.00%
Packaging
10G
Price
$7882.88
Updated
2021/12/16
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1-Indanone-6-carboxylic acid Chemical Properties,Usage,Production

Synthesis

38628-51-2

60031-08-5

The general procedure for the synthesis of 1-indanone-6-carboxylic acid from 4-(2-carboxyethyl)benzoic acid is as follows: 6-carboxy-1-indanone, which is the feedstock of Example 206, was prepared as follows: 3-(4-carboxyphenyl)propionic acid (5 g, 0.026 mol), fresh AlCl3 (25 g, 7.2 equivalents, 0.187 mol) and NaCl (2.5 g , 10% of the mass of AlCl3) were added to a 100 mL flask equipped with a condenser and an internal thermometer. The flask was shaken briefly to mix the solids well and subsequently heated in an oil bath set at 190°C. The reaction was maintained at an internal temperature of 180°C or above for 1 hour (the mixture melted to a dark brown liquid during the reaction). After the reaction was complete, the mixture was cooled and poured into a 2000 mL beaker containing ice and washed with water. 180mL of 6M HCl and 250mL of EtOAc were added and the layers were separated. The aqueous layer was extracted with EtOAc (3 x 200mL). The organic layers were combined, washed sequentially with 2M HCl, water and brine, dried with MgSO4, filtered and concentrated in vacuum to give a light brown solid 6-carboxy-1-indanone (4.10 g, 90% yield), which was used directly in the next synthesis.

References

[1] Patent: WO2005/87236, 2005, A1. Location in patent: Page/Page column 39
[2] Patent: US2010/249095, 2010, A1. Location in patent: Page/Page column 68-69
[3] Tetrahedron, 1995, vol. 51, # 1, p. 203 - 216
[4] Journal of the Chemical Society, 1956, p. 4647,3652
[5] Patent: US2012/71461, 2012, A1. Location in patent: Page/Page column 60

1-Indanone-6-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Indanone-6-carboxylic acid Suppliers

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View Lastest Price from 1-Indanone-6-carboxylic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1-Indanone-6-carboxylic acid 60031-08-5
Price
US $0.10-10.00/KG
Min. Order
0.10000000149011612KG
Purity
98%
Supply Ability
200TONS
Release date
2025-08-14
Career Henan Chemical Co
Product
1-Indanone-6-carboxylic acid 60031-08-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KGS
Release date
2019-12-25

60031-08-5, 1-Indanone-6-carboxylic acidRelated Search:

Methyl formate 1-Indanone Retinoic acid Chromium picolinate Bis(2-ethylhexyl) phthalate Calcium formate Benzoic acid Phthalic acid Isophthalic acid Anthranilic acid INDAN-5-CARBOXALDEHYDE 1-INDANONE-4-CARBOXYLIC ACID 6-Methyl-1-indanone 5-chloro-2-hydroxy-1-indanone-2-carboxylic acid methyl ester 1-Indanone-3-carboxylic Acid 5-HYDROXYMETHYLINDANE INDAN-5-CARBOXYLIC ACID CHEMBRDG-BB 6861500

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  • JR-8361, 2,3-Dihydro-3-oxo-1H-indene-5-carboxylic acid, 97%
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  • 1H-Indene-5-carboxylic acid, 2,3-dihydro-3-oxo-
  • 60031-08-5
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