(+)-(18-CROWN-6)-2,3,11,12-TETRACARBOXYLIC ACID Property

Melting point:

210-212 °C (lit.)

Boiling point:

798.9±60.0 °C(Predicted)

Density 

1.399±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer, Under Inert Atmosphere

solubility 

Methanol (Slightly), Water (Slightly)

pka

1.95±0.70(Predicted)

form 

Solid

color 

Off-White to Pale Yellow

optical activity

[α]20/D +62°, c = 1 in methanol

BRN 

4240375

Stability:

Hygroscopic

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2932990090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

(+)-(18-CROWN-6)-2,3,11,12-TETRACARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

(+)-(18-CROWN-6)-2,3,11,12-TETRACARBOXYLIC ACID is White Solid

Uses

(+)-(18-CROWN-6)-2,3,11,12-TETRACARBOXYLIC ACID is a calcium and barium chelator. A useful chiral NMR discriminating agent for underivatized amino acids

Uses

Derived tetracarboxylic acid chloride of this crown ether reacts with meta- and para-xylylene diamines to form chiral captands in high yields. Used as a chiral selector in capillary zone electrophoresis for the separation of a variety of optically active amines. Synthesis of monoamides.