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CASTICIN

Product Name
CASTICIN
CAS No.
479-91-4
Chemical Name
CASTICIN
Synonyms
CASTICIN;Casticine;CASTICIN(P);VITEXICARPIM;VITEXICARPIN;Casticin (6CI);Casticin (25 mg);CASTICIN WITH HPLC;CASTICIN USP/EP/BP;CASTICIN 479-91-4
CBNumber
CB4688714
Molecular Formula
C19H18O8
Formula Weight
374.34
MOL File
479-91-4.mol
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CASTICIN Property

Melting point:
186-187 °C
Boiling point:
617.7±55.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
ethanol: soluble1mg/mL, clear, colorless to light yellow
form 
Solid
pka
6.13±0.40(Predicted)
color 
Yellow
BRN 
1300392
InChI
InChI=1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3
InChIKey
PJQLSMYMOKWUJG-UHFFFAOYSA-N
SMILES
C1(C2=CC=C(OC)C(O)=C2)OC2=CC(OC)=C(OC)C(O)=C2C(=O)C=1OC
CAS DataBase Reference
479-91-4(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001724
Product name
Agnus castus fruit dry extract
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
350 mg
Price
$225
Updated
2025/07/31
Sigma-Aldrich
Product number
1096779
Product name
Casticin
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$935
Updated
2025/07/31
Sigma-Aldrich
Product number
01940590
Product name
Casticin
Purity
primary pharmaceutical reference standard
Packaging
10mg
Price
$524
Updated
2023/06/20
Cayman Chemical
Product number
16976
Product name
Casticin
Purity
≥98%
Packaging
1mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
16976
Product name
Casticin
Purity
≥98%
Packaging
5mg
Price
$184
Updated
2024/03/01
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CASTICIN Chemical Properties,Usage,Production

Chemical Properties

Soluble in a mixed solvent of DMSO, chloroform and methanol, insoluble in petroleum ether and chloroform. Derived from the Umbelliferae plant Foeniculum vulgare

Uses

Casticin is a biological compound known to induce human glioma cell death through an apoptotic mechanism and disruption of the mitotic cycle.

Definition

ChEBI: A tetramethoxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6, 7 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii.

in vivo

Casticin (20 mg/kg, p.o.) has toxic effect on the liver in mice with CCl4-and BDL-induced hepatic injury. Casticin attenuates liver fibrosis induced by CCl4 or BDL in vivo. Casticin inhibits HSC activation and collagen matrix expression by blocking TGF-β/Smad signaling in vivo[2].

CASTICIN Preparation Products And Raw materials

Raw materials

Preparation Products

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CASTICIN Suppliers

China 248 France 2 Germany 3 India 1 United Kingdom 5 United States 21 Global 280
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View Lastest Price from CASTICIN manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
CASTICIN 479-91-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-13
Shanghai Standard Technology Co., Ltd.
Product
Vitexicarpin 479-91-4
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-12
Career Henan Chemical Co
Product
Casticin 479-91-4
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-25

479-91-4, CASTICINRelated Search:

Taxifolin DIHYDRO CUMINYL ALCOHOL Shikonin Paclitaxel Pterostilbene Baicalein centaureidin 2-BENZYLOXY-4,5-DIMETHOXYBENZALDEHYDE ARTEMETIN 7-METHOXYFLAVONOL CASTICIN 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE ARTEMISININ SCUTELLAREIN 6-METHOXYFLAVONOL 2,4,5-Trimethoxybenzaldehyde TAMARIXETIN 6,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE

  • CASTICIN
  • 5,3'-DIHYDROXY-3,6,7,4'-TETRAMETHOXYFLAVONE
  • 3',5-DIHYDROXY-3,4',6,7-TETRAMETHOXY FLAVONE
  • VITEXICARPIN
  • VITEXICARPIM
  • Casticin (Vitexicarpin)
  • Casticin (25 mg)
  • CASTICIN WITH HPLC
  • (3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-
  • 4H-1-Benzopyran-4-one,5-hydroxy-2-
  • 3,4',6,7-Tetramethoxy-3',5-dihydroxyflavone
  • 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one
  • CASTICIN(P)
  • 4H-1-Benzopyran-4-one,5-hydroxy-2-(3-hydroxy-4-Methoxyphenyl)-3,6,7-triMethoxy-
  • Casticine
  • Quercetagetin 3,6,7,4′-tetramethyl ether
  • 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one
  • Agnus castus fruit dry extract
  • Casticin, 98%, from Vitex trifolia Linn. var. trifolia
  • CASTICIN USP/EP/BP
  • CASTICIN 479-91-4
  • Di-β-aminopropionitrile fumarate
  • β-Aminopropionitrile fumarate
  • β-Ammoniumpropionitrile hemifumarate
  • Casticin (6CI)
  • 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-chromen-4-one
  • Casticin, 10 mM in DMSO
  • 479-91-4
  • Hexa-substituted Flavones
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract