2-Hydroxyethyl methacrylate
- Product Name
- 2-Hydroxyethyl methacrylate
- CAS No.
- 868-77-9
- Chemical Name
- 2-Hydroxyethyl methacrylate
- Synonyms
- HEMA;GMA;HYDROXYETHYL METHACRYLATE;GLYCOL METHACRYLATE;ETHYLENE GLYCOL METHACRYLATE;BisoMer HEMA;N5-Methyl-L-glutamine;Hydroxyethyl Methacrylat;2-(Methacryloyloxy)ethanol;Hydroxyethyl methacrylate (HEMA)
- CBNumber
- CB4690827
- Molecular Formula
- C6H10O3
- Formula Weight
- 130.14
- MOL File
- 868-77-9.mol
2-Hydroxyethyl methacrylate Property
- Melting point:
- -12 °C
- Boiling point:
- 67 °C3.5 mm Hg(lit.)
- Density
- 1.073 g/mL at 25 °C(lit.)
- vapor density
- 5 (vs air)
- vapor pressure
- 0.01 mm Hg ( 25 °C)
- refractive index
- n20/D 1.453(lit.)
- Flash point:
- 207 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform, Methanol (Slightly)
- form
- Liquid
- pka
- 13.83±0.10(Predicted)
- color
- Clear
- Odor
- Ester like
- Water Solubility
- soluble
- FreezingPoint
- -20
- FreezingPoint
- -96
- Sensitive
- Air Sensitive
- BRN
- 1071583
- Stability:
- Unstable - may polymerize in the absence of stabilizer. May be stabilized with, or contain small amounts of, diethylene glycol monomethacrylate, di(ethylene glycol)dimethacrylate, methacrylic acid. Incompatible with strong oxidizing agents, free radical initiators, peroxides, steel. Closed containers may explode if heated due to runaway polymer
- InChIKey
- WOBHKFSMXKNTIM-UHFFFAOYSA-N
- LogP
- 0.42 at 25℃
- CAS DataBase Reference
- 868-77-9(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Hydroxyethyl methacrylate(868-77-9)
- EPA Substance Registry System
- 2-Hydroxyethyl methacrylate (868-77-9)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/38-43-36/37/38
- Safety Statements
- 26-36/37-28A-28
- WGK Germany
- 1
- RTECS
- OZ4725000
- TSCA
- Yes
- HS Code
- 29161490
- Hazardous Substances Data
- 868-77-9(Hazardous Substances Data)
- Toxicity
- LD50 orally in Rabbit: 5050 mg/kg LD50 dermal Rabbit > 3000 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.00588
- Product name
- 2-Hydroxyethyl methacrylate
- Purity
- (stabilised with hydroquinone monomethyl ether) for synthesis
- Packaging
- 250ML
- Price
- $60.3
- Updated
- 2024/03/01
- Product number
- 8.00588
- Product name
- 2-Hydroxyethyl methacrylate
- Purity
- (stabilised with hydroquinone monomethyl ether) for synthesis
- Packaging
- 2.5L
- Price
- $132
- Updated
- 2024/03/01
- Product number
- 17348
- Product name
- 2-Hydroxyethyl methacrylate
- Purity
- embedding medium (for microscopy)
- Packaging
- 250ML
- Price
- $115
- Updated
- 2024/03/01
- Product number
- 128635
- Product name
- 2-Hydroxyethyl methacrylate
- Purity
- contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%
- Packaging
- 1kg
- Price
- $52
- Updated
- 2024/03/01
- Product number
- 128635
- Product name
- 2-Hydroxyethyl methacrylate
- Purity
- contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%
- Packaging
- 18kg
- Price
- $547
- Updated
- 2024/03/01
2-Hydroxyethyl methacrylate Chemical Properties,Usage,Production
Chemical Properties
colourless liquid
Uses
2-Hydroxyethyl methacrylate is the methacrylic monomer for use in UV inks, adhesives, lacquers, dental materials, artificial nails, etc.
Uses
2-Hydroxyethyl methacrylate is used in UV-curable inks and coatings. It is also used in adhesives, artificial nails, dental materials and lacquers. In dentistry, it is one of the main volatile acrylates along with methyl methacrylate. Further, it is used as a monomer in the synthesis of polymers for dental prosthetics and for geotechnical grouting in construction work.
Uses
2-Hydroxyethyl methacrylate is used for preparation of hydrophilic polymers for biomedical devices.
Definition
2-Hydroxyethyl methacrylate is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.
General Description
2-Hydroxyethyl methacrylate (HEMA) is biocompatible in nature. Polymeric hydrogel scaffold can be produced by polymerizing HEMA in water.
Hazard
30% grade (with xylene): Flammable, moderate fire risk.
Environmental Fate
2-Hydroxyethyl methacrylate's production and use in acrylic resins, enamels, and as a binder for non-woven fabrics may result in its release to the environment through various waste streams. If released into the air, a vapor pressure of 0.126 mm Hg at 25 °C indicates that 2-hydroxyethyl methacrylate will exist solely as a vapor in the ambient atmosphere. Vapor-phase 2-hydroxyethyl methacrylate will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 16 hours. If released to soil, 2-hydroxyethyl methacrylate is expected to have very high mobility based upon an estimated Koc of 43. Volatilization from moist soil surfaces is not expected to be an important fate process based upon an estimated Henry's Law constant of 4.6X10-9 atm-cu m/mole. 2-Hydroxyethyl methacrylate is not expected to volatilize from dry soil surfaces based on its vapor pressure. If released into water, 2-hydroxyethyl methacrylate is not expected to adsorb to suspended solids and sediment in the water column based on the estimated Koc. 2-Hydroxyethyl methacrylate reached 92-100% of its theoretical BOD in 2 weeks using an activated sludge inoculum. Volatilization from water surfaces is not expected to be a necessary fate process based on this compound's estimated Henry's Law constant. An estimated BCF of 1.3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis of 2-hydroxyethyl methacrylate may be a significant process under basic conditions based upon a hydrolytic half-life of 4 hours at pH 11 for the structurally similar butyl acrylate; half-lives for butyl acrylate at pH 7, 8, and 9 were 4 years, 150 days, and 15 days, respectively. Occupational exposure to 2-hydroxyethyl methacrylate may occur through inhalation and dermal contact with this compound at workplaces where 2-hydroxyethyl methacrylate is produced or used. The general population may be exposed to 2-hydroxyethyl methacrylate via inhalation or dermal contact with acrylic resins or enamels containing this compound.
Metabolism
2-hydroxyethyl methacrylate (HEMA) is a monomer based on methacrylic acid (MAA) used to produce biomaterials such as dental adhesive and composite resins. The process of polymerization, which is run in situ, is always incomplete, resulting in the presence of free monomers in the oral cavity. Moreover, monomers can be released from polymer-based tooth restorations through mechanical shearing and enzymatic degradation of polymers. They may penetrate the pulp through microchannels in the dentin structure. HEMA, like many of MAA-based monomers, is an ester, so it can be targeted by esterases when in organism and can undergo degradation. The main product of HEMA hydrolysis is MAA, which may undergo further degradation producing several intermediates of potential biological activity[1].
Purification Methods
Dissolve the ester in water and extract with n-heptane to remove ethylene glycol dimethacrylate (checked by gas-liquid chromatography and by NMR) and distil it twice under reduced pressure [Strop et al. J Phys Chem 80 694 1976]. [Beilstein 2 IV 1530.]
Toxics Screening Level
The ITSL can be determined from the mouse LD50 from Tanii and Hashimoto using the
equation from R232(1)(h) as follows.
ITSL = (5887 mg/kg)/( 500x 40 x 100 x 0.167) x 1kg/1.7m3 = 10 μg/m3 annual average.
The default mouse inhalation rate of 1.7 m3/kg was used in the above calculation.
2-Hydroxyethyl methacrylate Preparation Products And Raw materials
Raw materials
Preparation Products
2-Hydroxyethyl methacrylate Suppliers
- Tel
- 400-400-6206333 18521732826
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 0532-0532-86867058 18562606086
- Fax
- 0532-86867058
- sales@qdrenas.com
- Country
- China
- ProdList
- 128
- Advantage
- 50
- Tel
- 021-69185552 13701777608
- Fax
- 021-69186006
- kangtuochem@163.com
- Country
- China
- ProdList
- 4360
- Advantage
- 55
- Tel
- 19371278702
- n13164103386@163.com
- Country
- China
- ProdList
- 511
- Advantage
- 58
- Tel
- 020-82567763 13609796592
- summitchem@163.com
- Country
- China
- ProdList
- 20
- Advantage
- 58
- Tel
- 19357188251; 19357188251
- 1605755801@qq.com
- Country
- China
- ProdList
- 24
- Advantage
- 58
- Tel
- 15651337098
- 15651337098@163.com
- Country
- China
- ProdList
- 4468
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 010-89508211 18501085097
- Fax
- 010-89508210
- sales.bj@hwrkchemical.com
- Country
- China
- ProdList
- 8418
- Advantage
- 55
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44689
- Advantage
- 61
- Tel
- 010-82967028 13552068683
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12390
- Advantage
- 60
- Tel
- 18951621803
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 19185
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42958
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 15527768850
- 1791901229@qq.com
- Country
- China
- ProdList
- 8835
- Advantage
- 52
- Tel
- 010-82954736 13391601435
- sales@isomersyn.com
- Country
- China
- ProdList
- 3295
- Advantage
- 57
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18738
- Advantage
- 57
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9815
- Advantage
- 79
- Tel
- 0086-755-86198205
- acinfo@aemonchem.com
- Country
- China
- ProdList
- 1931
- Advantage
- 57
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 021-021-021-67601398-809-809-809 15221380277
- Fax
- 021-57711696
- marketing_china@spectrumchemical.com
- Country
- China
- ProdList
- 9658
- Advantage
- 60
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4940
- Advantage
- 60
- Tel
- 4008-755-333 18080918076
- Fax
- 028-86757656
- 800078821@qq.com
- Country
- China
- ProdList
- 9718
- Advantage
- 55
- Tel
- 0755-4000505016 13380397412
- Fax
- 0755 28094224
- 3001272453@qq.com
- Country
- China
- ProdList
- 5047
- Advantage
- 50
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17770
- Advantage
- 75
- Tel
- 400-810-7969 010-59572699
- Fax
- 010-59572688
- ningzi.li@inno-chem.com.cn
- Country
- China
- ProdList
- 6134
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 22514
- Advantage
- 55
- Tel
- 86 592 2680277
- Fax
- 0086 592 2680237
- sale@simagchem.com
- Country
- China
- ProdList
- 430
- Advantage
- 55
- Tel
- 021-61552785
- Fax
- 021-55660885
- sales@shshiji.com
- Country
- China
- ProdList
- 9545
- Advantage
- 55
- Tel
- 0570-3066667
- Fax
- 0570-3063388
- Country
- China
- ProdList
- 3930
- Advantage
- 58
- Tel
- 400-8706899
- Fax
- 400-8706899
- hysj_bj.com
- Country
- China
- ProdList
- 3583
- Advantage
- 55
- Tel
- 021-60549325 18616193163
- Fax
- 021-33250306
- Country
- China
- ProdList
- 4526
- Advantage
- 56
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- 422131432@qq.com
- Country
- China
- ProdList
- 9978
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41462
- Advantage
- 60
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- Country
- China
- ProdList
- 2930
- Advantage
- 58
- Tel
- 021-54359730 400-008-9730
- Fax
- 021-54353864
- info@chemxyz.com
- Country
- China
- ProdList
- 3991
- Advantage
- 60
- Tel
- 010-51268198
- Fax
- 010-63833209
- leadershipchem@126.com
- Country
- China
- ProdList
- 2546
- Advantage
- 58
- Tel
- 0371-13526885213 15637198702
- Fax
- 0371-63709726
- xpkchem@163.com
- Country
- China
- ProdList
- 3980
- Advantage
- 58
- Tel
- 021-58958189
- Fax
- 021-58957967
- wouchina@126.com
- Country
- China
- ProdList
- 2666
- Advantage
- 55
- Tel
- 0755-0755-66853366 13670046396
- Fax
- 0755-28363542
- sales@chem-strong.com
- Country
- China
- ProdList
- 18084
- Advantage
- 56
- Tel
- 021-58957966 18930537195
- Fax
- 021-60899437
- wouchina@126.com
- Country
- China
- ProdList
- 3027
- Advantage
- 58
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 021-60899189-8001 18918189673
- Fax
- 021-60899304
- gtchem@126.com
- Country
- China
- ProdList
- 2656
- Advantage
- 58
View Lastest Price from 2-Hydroxyethyl methacrylate manufacturers
- Product
- 2-Hydroxyethyl methacrylate 868-77-9
- Price
- US $999.00-666.00/ton
- Min. Order
- 1ton
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-08-20
- Product
- 2-Hydroxyethyl methacrylate 868-77-9
- Price
- US $99.00-66.00/kg
- Min. Order
- 0.0010000000474974513kg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-08-19
- Product
- 2-Hydroxyethyl methacrylate，HEMA 868-77-9
- Price
- US $0.00/KG
- Min. Order
- 200KG
- Purity
- 98
- Supply Ability
- 10mt
- Release date
- 2020-12-28