Benzamidine hydrochloride hydrate
- Product Name
- Benzamidine hydrochloride hydrate
- CAS No.
- 206752-36-5
- Chemical Name
- Benzamidine hydrochloride hydrate
- Synonyms
- BENZAMIDINE HCL HYDRATE;Imino(phenyl)methylamine;BENZAMIDINIUM CHLORIDE HYDRATE;BENZAMIDINE HYDROCHLORIDE HYDRATE;[amino(phenyl)methylidene]azanium;BENZAMIDINE HYDROCHLORIDE N-HYDRATE;AMIDINOBENZENE HYDROCHLORIDE HYDRATE;BENZAMIDINE HYDROCHLORIDE HYDRATE FO;BENZAMIDINE HYDROCHLORIDE MONOHYDRATE;Benzamidine hydrochloride hydrate,98%
- CBNumber
- CB4694173
- Molecular Formula
- C7H11ClN2O
- Formula Weight
- 174.63
- MOL File
- 206752-36-5.mol
Benzamidine hydrochloride hydrate Property
- Melting point:
- 86-88 °C(lit.)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble50mg/mL, clear to slightly hazy, colorless to faintly yellow
- form
- Powder
- color
- White to off-white
- PH
- 5 (50g/l, H2O, 20℃)
- Water Solubility
- soluble
- Sensitive
- Hygroscopic
- BRN
- 3594959
- CAS DataBase Reference
- 206752-36-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- CV6260000
- F
- 3-21
- TSCA
- Yes
- HS Code
- 2925 29 00
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 8.20122
- Product name
- Benzamidine hydrochloride hydrate
- Purity
- for synthesis
- Packaging
- 2g
- Price
- $41.8
- Updated
- 2024/03/01
- Product number
- 8.20122
- Product name
- Benzamidine hydrochloride hydrate
- Purity
- for synthesis
- Packaging
- 25g
- Price
- $125
- Updated
- 2024/03/01
- Product number
- 8.20122
- Product name
- Benzamidine hydrochloride hydrate
- Purity
- for synthesis
- Packaging
- 1kg
- Price
- $1250
- Updated
- 2024/03/01
- Product number
- A16002
- Product name
- Benzamidine hydrochloride hydrate, 98%, water ca 10-14%
- Packaging
- 5g
- Price
- $27.65
- Updated
- 2024/03/01
- Product number
- A16002
- Product name
- Benzamidine hydrochloride hydrate, 98%, water ca 10-14%
- Packaging
- 25g
- Price
- $78
- Updated
- 2024/03/01
Benzamidine hydrochloride hydrate Chemical Properties,Usage,Production
Chemical Properties
white fine crystalline powder
Uses
Benzamidine hydrochloride hydrate is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases. It is a proteolytic inhibitor and apoptosis reagent.
Uses
Benzamidine hydrochloride hydrate has been used:
- in western blot analysis
- in immunoprecipitation
- in the purification of yeast dynein
- as a protease inhibitor in the preparation of brush-border membrane vesicles
- for the processing of human synovial fluid, blood and eye sleep
- to prevent non-specific degradation of cartilages
Application
Benzamidine hydrochloride hydrate has been used:
in western blot analysis
in immunoprecipitation
in the purification of yeast dynein
as a protease inhibitor in the preparation of brush-border membrane vesicles
for the processing of human synovial fluid, blood and eye sleep
to prevent non-specific degradation of cartilages
Biological Activity
Peptidase inhibitor.
Benzamidine HCl is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases.A concentration of approximately 1 mM is used for general protease inhibition. To inhibit proteases from yeast, a range of 0.5 to 4.0 mM is used and it is for the most part interchangeable with pepstatin A.
In addition to being a strong competitive inhibitor of trypsin, benzamidine HCl has been also shown to be a strong competitive inhibitor of thrombin and plasmin. It was also found to be as effective as aprotinin in the prevention of glucagon degradation in human plasma.
Biochem/physiol Actions
Peptidase inhibitor.
Purification Methods
Recrystallise it from dilute HCl (crystals contain xH2O) or EtOH/few drops HCl; dry it in a vacuum. It is a proteolytic inhibitor [Jeffcoate & White J Clin Endocrinol Metab 38 155 1974, Beilstein 9 IV 898.]
Preparation and handling
Benzamidine HCl is soluble in water and alcohol. Solubility testing in water at a concentration of 50 mg/ml yields a clear solution with heating. Benzamidine HCl is sensitive to oxidation. It is recommended to prepare solutions fresh each time in degassed water prior to use. However, frozen aliquots stored under inert gas, to exclude air, may be stable for a short time. Insufficient information is available to assess the shelf-life of a frozen solution.
Precautions
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is hygroscopic in nature.
Benzamidine hydrochloride hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Benzamidine hydrochloride hydrate manufacturers
- Product
- Benzamidine hydrochloride hydrate 206752-36-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 5000kgs/month
- Release date
- 2021-10-28
- Product
- Benzamidine hydrochloride hydrate 206752-36-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- Benzamidine hydrochloride hydrate 206752-36-5
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-24