ChemicalBook > CAS DataBase List > 1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER

1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER

Product Name
1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER
CAS No.
215597-35-6
Chemical Name
1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER
Synonyms
1, 1-ACCB(OME);Methyl 1-aMinocyclobutanecarboxylate;methyl 1-aminocyclobutane-1-carboxylate;1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER;Cyclobutanecarboxylic acid, 1-aMino-, Methyl ester;Cyclobutanecarboxylic acid, 1-amino-, methyl ester (9CI);1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER USP/EP/BP;Cyclobutanecarboxylicacid, 1-amino-, methyl ester, hydrochlo...
CBNumber
CB4710963
Molecular Formula
C6H11NO2
Formula Weight
129.16
MOL File
215597-35-6.mol
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1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER Property

Boiling point:
162.3±23.0 °C(Predicted)
Density 
1.127±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka
7.71±0.20(Predicted)
form 
Solid
Appearance
Colorless to light yellow Liquid
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Safety

Hazard Codes 
Xn
Risk Statements 
22
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A596345
Product name
1-Amino-cyclobutanecarboxylicacidmethylester
Packaging
250mg
Price
$240
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA148096
Product name
1-Amino-cyclobutanecarboxylic acid methylester
Packaging
25mg
Price
$56
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA148096
Product name
1-Amino-cyclobutanecarboxylic acid methylester
Packaging
50mg
Price
$98
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA148096
Product name
1-Amino-cyclobutanecarboxylic acid methylester
Packaging
100mg
Price
$170
Updated
2021/12/16
Matrix Scientific
Product number
074125
Product name
1-Amino-cyclobutanecarboxylic acid methyl ester
Purity
95+%
Packaging
1g
Price
$300
Updated
2021/12/16
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1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

67-56-1

120728-10-1

215597-35-6

Stage 1: Synthesis of methyl 1-aminocyclobutanecarboxylate Concentrated H2SO4 (10 ml) was slowly added to a methanol solution (30 ml) containing 1-(tert-butoxycarbonylamino)-cyclobutane-1-carboxylic acid (9.29 mmol, 1 eq.) at 0°C. The reaction mixture was refluxed at 0°C for 2 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in distilled water and the pH was adjusted to 8-9 with saturated sodium bicarbonate solution, followed by extraction with ethyl acetate (2 x 200 ml). The combined organic phases were washed sequentially with distilled water (2 x 150 ml) and saturated NaCl solution (2 x 50 ml) and dried with anhydrous sodium sulfate. Finally, the solvent was removed by concentration under reduced pressure to afford methyl 1-aminocyclobutanecarboxylate as a white solid in 75% yield.

References

[1] Patent: US2010/173889, 2010, A1. Location in patent: Page/Page column 34

1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER Suppliers

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215597-35-6, 1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTERRelated Search:


  • 1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER
  • 1, 1-ACCB(OME)
  • Cyclobutanecarboxylic acid, 1-amino-, methyl ester (9CI)
  • Cyclobutanecarboxylic acid, 1-aMino-, Methyl ester
  • Methyl 1-aMinocyclobutanecarboxylate
  • methyl 1-aminocyclobutane-1-carboxylate
  • 1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER USP/EP/BP
  • Cyclobutanecarboxylicacid, 1-amino-, methyl ester, hydrochlo...
  • 215597-35-6
  • AMINEPRIMARY
  • AMINOACID
  • pharmacetical