ChemicalBook > CAS DataBase List > 3,5-Diaminobenzoic acid

3,5-Diaminobenzoic acid

Product Name: 3,5-Diaminobenzoic acid
CAS No.: 535-87-5
Chemical Name: 3,5-Diaminobenzoic acid
Synonyms: 3,5-DABA;3,5-DiaMinoben;3, 5-2 aMino acid;DiaMinobenzoic aci;3,5-Diaminobenzoic a;3,5-DIACETYLPYRAZINE;3,5-eranjibenjiasuan;3,5-diamino-benzoicaci;3,5-DIAMINOBENZOIC ACID;3,5-Diaminebenzoic acid
CBNumber: CB4718646
Molecular Formula: C7H8N2O2
Formula Weight: 152.15
MOL File: 535-87-5.mol

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3,5-Diaminobenzoic acid Property

Melting point:: 235-238 °C (dec.) (lit.)
Boiling point:: 274.61°C (rough estimate)
Density: 1.2804 (rough estimate)
vapor pressure: 0Pa at 25℃
refractive index: 1.5200 (estimate)
Flash point:: 235-240°C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Sparingly), Methanol (Slightly)
form: Powder
pka: pK1:5.30 (25°C)
color: White to gray
Water Solubility: Very soluble in water.
Decomposition: 235-240 ºC
Merck: 14,2978
BRN: 2086484
InChIKey: UENRXLSRMCSUSN-UHFFFAOYSA-N
LogP: -0.51
CAS DataBase Reference: 535-87-5(CAS DataBase Reference)
EPA Substance Registry System: Benzoic acid, 3,5-diamino- (535-87-5)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: DG6186000
Hazard Note: Irritant
TSCA: Yes
HS Code: 29224995

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D12805
Product name: 3,5-Diaminobenzoic acid
Purity: 98%
Packaging: 100g
Price: $63.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: D12805
Product name: 3,5-Diaminobenzoic acid
Purity: 98%
Packaging: 1kg
Price: $627
Updated: 2025/07/31

TCI Chemical

Product number: D0294
Product name: 3,5-Diaminobenzoic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $71
Updated: 2025/07/31

TCI Chemical

Product number: D0294
Product name: 3,5-Diaminobenzoic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 100g
Price: $185
Updated: 2025/07/31

TCI Chemical

Product number: D0294
Product name: 3,5-Diaminobenzoic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 500g
Price: $555
Updated: 2025/07/31

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3,5-Diaminobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

White to grey powder

Uses

3,5-diaminobenzoic acid be used as organic intermediates.

Uses

3,5-Diaminobenzoic acid is an analog of diatriazoate, which has been shown to have antigenicity properties towards the monoclonal antibodies. It is used as pharmaceutical intermediate.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

99-34-3

535-87-5

General procedure for the synthesis of 3,5-diaminobenzoic acid from 3,5-dinitrobenzoic acid: 3,5-dinitrobenzoic acid (51 g, 0.24 mol) and 300 mL of water were added to a 1 L stainless steel high-pressure reactor and stirred thoroughly until homogeneous. Subsequently, the pH of the reaction system was adjusted to 7-8 using an aqueous sodium hydroxide solution with a mass percent concentration of 20%. 0.25 g of Ni-Yb-Al triple-acting catalyst was added followed by three nitrogen substitutions to remove air. The hydrogen pressure was controlled at 0.2 MPa and the reaction temperature was maintained at 25-30 °C until the reaction pressure decreased significantly, indicating the completion of the reaction. Upon completion of the reaction, the catalyst was recovered by filtration. The filtrate was adjusted to pH 3 with concentrated hydrochloric acid to precipitate the target product 3,5-diaminobenzoic acid. The solid product was collected by filtration, washed with water and finally dried under vacuum to give 36.5 g of 3,5-diaminobenzoic acid in 98.8% yield and 98.9% HPLC purity. The retention time of the product was consistent with the standard control.

Purification Methods

Crystallise the acid from water. The dihydrochloride has m 226-228o(dec). [Beilstein 14 H 453, 14 III 1179, 14 IV 1304.]

References

[1] Patent: CN105949076, 2016, A. Location in patent: Paragraph 0025; 0026; 0031; 0036; 0040; 0045; 0053
[2] Journal of the Iranian Chemical Society, 2014, vol. 11, # 6, p. 1587 - 1592
[3] Synthetic Communications, 2000, vol. 30, # 20, p. 3639 - 3644
[4] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000, vol. 39, # 9, p. 709 - 711
[5] Synthetic Communications, 2003, vol. 33, # 2, p. 281 - 289

3,5-Diaminobenzoic acid Preparation Products And Raw materials

Raw materials

Benzoic acid

Preparation Products

DIATRIZOIC ACID

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3,5-Diaminobenzoic acid Suppliers

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View Lastest Price from 3,5-Diaminobenzoic acid manufacturers

CHINATECH(TIANJIN) CHEMICAL CO.,LTD.

Product: 3,5’-Diaminobenzoic acid 535-87-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ≥99%&99.5%
Supply Ability: 1000
Release date: 2025-10-27

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: 3,5-Diaminobenzoic acid 535-87-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 20tons
Release date: 2025-08-21

Asia Chem I and E (Jiangsu) Co Ltd

Product: 3,5-Diaminobenzoic acid 535-87-5
Price: US $36.28/Kg/Drum
Min. Order: 25Kg/Drum
Purity: 99.50%HPLC
Supply Ability: 10tons/month
Release date: 2025-07-08

535-87-5, 3,5-Diaminobenzoic acidRelated Search:

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3,5-Diaminobenzoic acid 535-87-5

3,5-eranjibenjiasuan

3,5-Diaminobenzoic Acid &gt

3,5-Diaminobenzoic acid USP/EP/BP

3,5-Diaminobenzoic Acid extrapure, 98%

3,5-Diaminobenzoic acid,NA

Sarpogrelate Imurity 4 Monomer

3,5'-Diaminobenzoic acid

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535-87-5

H2N2C6H3COOH

Fluorescent Probes, Labels, Particles and Stains

Fluorescent Labels

Other Fluorescent Labels

Biochemicals and Reagents

BioChemical

Aromatic Amino AcidsFluorescent Probes, Labels, Particles and Stains

Fluorescent Labels

Other Fluorescent Labels

Peptide Synthesis

Organic acids

Unnatural Amino Acid Derivatives

535-87-5