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Ciprofloxacin hydrochloride hydrate

Product Name
Ciprofloxacin hydrochloride hydrate
CAS No.
86393-32-0
Chemical Name
Ciprofloxacin hydrochloride hydrate
Synonyms
Ciprofloxacin hydrochloride CRS;Monohydrochloride monohydrate;Ceprimax;Oftacilox;Ciprooxacin HCL;Ciprofloxcin hcl;oride Monohydrate;Ciprofloxaicin HCL;Ciprofloxacin-d8 HCl;CIPROFLOXACIN HCL USP
CBNumber
CB4740508
Molecular Formula
C17H21ClFN3O4
Formula Weight
385.82
MOL File
86393-32-0.mol
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Ciprofloxacin hydrochloride hydrate Property

Melting point:
318-320 °C
RTECS 
VB1993800
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Soluble in water, slightly soluble in methanol, very slightly soluble in anhydrous ethanol, practically insoluble in acetone, in ethyl acetate and in methylene chloride.
form 
Solid
color 
White to Light yellow
PH
pH (25g/l, 25℃) 3.0~4.5
Water Solubility 
Soluble in water (35mg/ml).
Merck 
14,2314
InChIKey
DIOIOSKKIYDRIQ-UHFFFAOYSA-N
CAS DataBase Reference
86393-32-0(CAS DataBase Reference)
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Safety

WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933595960
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1044
Product name
Ciprofloxacin HCl
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
1g
Price
$114
Updated
2024/03/01
Sigma-Aldrich
Product number
1134335
Product name
Ciprofloxacin hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
400mg
Price
$436
Updated
2024/03/01
TCI Chemical
Product number
C2227
Product name
Ciprofloxacin Hydrochloride Monohydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$57
Updated
2024/03/01
TCI Chemical
Product number
C2227
Product name
Ciprofloxacin Hydrochloride Monohydrate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$149
Updated
2024/03/01
Alfa Aesar
Product number
J61970
Product name
Ciprofloxacin hydrochloride
Packaging
5g
Price
$71.6
Updated
2024/03/01
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Ciprofloxacin hydrochloride hydrate Chemical Properties,Usage,Production

Chemical Properties

Pale yellow, crystalline, slightly hygroscopic powder.

Uses

Ciprofloxacin hydrochloride has been suggested as a treatment for a wide range of infections caused by susceptible organisms including infections of urinary, respiratory, and gastrointestinal tracts, gonorrhoea and septicaemia. Nalidixic acid analogue.

Uses

Fluoroquinolone antibacterial.

Application

Ciprofloxacin hydrochloride hydrate is a broad-spectrum antibiotic that inhibits bacterial DNA gyrase and blocks DNA synthesis and replication, resulting in bacterial death. It has strong antibacterial activity against Escherichia coli, Klebsiella and other Enterobacteriaceae; the antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae is better than norfloxacin and pefloxacin.

Definition

ChEBI: The monohydrate form of ciprofloxacin monohydrochloride.

brand name

Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).

General Description

Ciprofloxacin HCl is a fluoroquinolone antibiotic agent, which shows a broad spectrum of antibacterial activity against gram positive and gram negative bacteria.

in vitro

Ciprofloxacin (hydrochloride monohydrate) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. Ciprofloxacin (hydrochloride monohydrate) (CIP) shows potent activity against Y. pestis with MIC 90 of 0.03 μg/mL.

in vivo

Ciprofloxacin (hydrochloride monohydrate) (1 mg/L) induces glutathione-S-transferase (GST) activity, in contrast with inhibited GST and Catalase (CAT) of larvae exposed to enrofloxacin. Ciprofloxacin (hydrochloride monohydrate) (≥10 μg/L) is ecotoxic for development, growth, detoxifying, and oxidative stress enzymes in anuran amphibian larvae. In a murine model of pneumonic plague, Ciprofloxacin (hydrochloride monohydrate) (30 mg/kg, i.p.) results in a drug exposure which is similar to the drug exposure observed in human following a 500 mg dose of oral Ciprofloxacin (hydrochloride monohydrate). Intraperitoneal Ciprofloxacin (hydrochloride monohydrate) reduces the lung bacterial load compare to controls treated with intraperitoneal PBS.

Ciprofloxacin hydrochloride hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ciprofloxacin hydrochloride hydrate Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
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Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
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Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
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59
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
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Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
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View Lastest Price from Ciprofloxacin hydrochloride hydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ciprofloxacin Hydrochloride 86393-32-0
Price
US $0.00/Kg/Drum
Min. Order
25KG
Purity
98%-102%; EP
Supply Ability
1000 KG
Release date
2021-05-31
Apeloa production Co.,Limited
Product
Ciprofloxacin Hydrochloride hydrate 86393-32-0
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
40000
Release date
2024-06-03
Hebei Weibang Biotechnology Co., Ltd
Product
Ciprofloxacin hydrochloride hydrate 86393-32-0
Price
US $1.00/PCS
Min. Order
1PCS
Purity
99%
Supply Ability
100mt
Release date
2024-11-04

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