ChemicalBook > CAS DataBase List > Ciprofloxacin hydrochloride hydrate

Ciprofloxacin hydrochloride hydrate

Product Name
Ciprofloxacin hydrochloride hydrate
CAS No.
86393-32-0
Chemical Name
Ciprofloxacin hydrochloride hydrate
Synonyms
Ciprofloxacin hydrochloride CRS;Monohydrochloride monohydrate;Ceprimax;Oftacilox;Ciprooxacin HCL;Ciprofloxcin hcl;oride Monohydrate;Ciprofloxaicin HCL;Ciprofloxacin-d8 HCl;CIPROFLOXACIN HCL USP
CBNumber
CB4740508
Molecular Formula
C17H21ClFN3O4
Formula Weight
385.82
MOL File
86393-32-0.mol
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Ciprofloxacin hydrochloride hydrate Property

Melting point:
318-320 °C
RTECS 
VB1993800
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Soluble in water, slightly soluble in methanol, very slightly soluble in anhydrous ethanol, practically insoluble in acetone, in ethyl acetate and in methylene chloride.
color 
White to Light yellow
PH
pH (25g/l, 25℃) 3.0～4.5
Water Solubility 
Soluble in water (35mg/ml).
Merck 
14,2314
InChIKey
DIOIOSKKIYDRIQ-UHFFFAOYSA-N
CAS DataBase Reference
86393-32-0(CAS DataBase Reference)
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Safety

WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933595960
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1044
Product name
Ciprofloxacin HCl
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
1g
Price
$114
Updated
2024/03/01
Sigma-Aldrich
Product number
1134335
Product name
Ciprofloxacin hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
400mg
Price
$436
Updated
2024/03/01
TCI Chemical
Product number
C2227
Product name
Ciprofloxacin Hydrochloride Monohydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$57
Updated
2024/03/01
TCI Chemical
Product number
C2227
Product name
Ciprofloxacin Hydrochloride Monohydrate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$149
Updated
2024/03/01
Alfa Aesar
Product number
J61970
Product name
Ciprofloxacin hydrochloride
Packaging
5g
Price
$71.6
Updated
2024/03/01
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Ciprofloxacin hydrochloride hydrate Chemical Properties,Usage,Production

Chemical Properties

Pale yellow, crystalline, slightly hygroscopic powder.

Uses

Ciprofloxacin hydrochloride has been suggested as a treatment for a wide range of infections caused by susceptible organisms including infections of urinary, respiratory, and gastrointestinal tracts, gonorrhoea and septicaemia. Nalidixic acid analogue.

Uses

Fluoroquinolone antibacterial.

Application

Ciprofloxacin hydrochloride hydrate is a broad-spectrum antibiotic that inhibits bacterial DNA gyrase and blocks DNA synthesis and replication, resulting in bacterial death. It has strong antibacterial activity against Escherichia coli, Klebsiella and other Enterobacteriaceae; the antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae is better than norfloxacin and pefloxacin.

Definition

ChEBI: The monohydrate form of ciprofloxacin monohydrochloride.

brand name

Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).

General Description

Ciprofloxacin HCl is a fluoroquinolone antibiotic agent, which shows a broad spectrum of antibacterial activity against gram positive and gram negative bacteria.

in vitro

Ciprofloxacin (hydrochloride monohydrate) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. Ciprofloxacin (hydrochloride monohydrate) (CIP) shows potent activity against Y. pestis with MIC 90 of 0.03 μg/mL.

in vivo

Ciprofloxacin (hydrochloride monohydrate) (1 mg/L) induces glutathione-S-transferase (GST) activity, in contrast with inhibited GST and Catalase (CAT) of larvae exposed to enrofloxacin. Ciprofloxacin (hydrochloride monohydrate) (≥10 μg/L) is ecotoxic for development, growth, detoxifying, and oxidative stress enzymes in anuran amphibian larvae. In a murine model of pneumonic plague, Ciprofloxacin (hydrochloride monohydrate) (30 mg/kg, i.p.) results in a drug exposure which is similar to the drug exposure observed in human following a 500 mg dose of oral Ciprofloxacin (hydrochloride monohydrate). Intraperitoneal Ciprofloxacin (hydrochloride monohydrate) reduces the lung bacterial load compare to controls treated with intraperitoneal PBS.

Ciprofloxacin hydrochloride hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ciprofloxacin hydrochloride hydrate Suppliers

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View Lastest Price from Ciprofloxacin hydrochloride hydrate manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Ciprofloxacin hydrochloride hydrate 86393-32-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-04-07
Sigma Audley
Product
Ciprofloxacin hydrochloride hydrate 86393-32-0
Price
US $35.00-25.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
200tons/year
Release date
2024-03-14
Hebei Yanxi Chemical Co., Ltd.
Product
Ciprofloxacin HCl hydrate 86393-32-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2023-09-20

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  • 86393-32-0
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