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CILAZAPRIL

Product Name
CILAZAPRIL
CAS No.
92077-78-6
Chemical Name
CILAZAPRIL
Synonyms
Justor;Dynorm;Vascase;Initiss;Inhibace;Cilazapril CRS;CILAZAPRIL EPC(;Cilazapril Hydrate;Vascace monohydrate;Inhibace monohydrate
CBNumber
CB4771690
Molecular Formula
C22H33N3O6
Formula Weight
435.51
MOL File
92077-78-6.mol
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CILAZAPRIL Property

Melting point:
98° (dec)
alpha 
D20 -62.51° (c = 1% in ethanol)
storage temp. 
Store at -20°C
solubility 
Slightly soluble in water, freely soluble in methanol and in methylene chloride.
pka
pKa1 3.3; pKa2 6.4(at 25℃)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C2174000
Product name
Cilazapril
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
c2174000
Price
$153
Updated
2024/03/01
Biosynth Carbosynth
Product number
FC34997
Product name
Cilazapril monohydrate
Packaging
25mg
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC34997
Product name
Cilazapril monohydrate
Packaging
10mg
Price
$95
Updated
2021/12/16
ChemScene
Product number
CS-2448
Product name
Cilazaprilmonohydrate
Purity
99.44%
Packaging
10mg
Price
$108
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC34997
Product name
Cilazapril monohydrate
Packaging
5mg
Price
$60
Updated
2021/12/16
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CILAZAPRIL Chemical Properties,Usage,Production

Description

Cilazapril is a new ACE inhibitor useful in the management of mild to moderate hypertension. Orally administered cilazapril is a prodrug which is de-esterified to its active diacid metabolite cilazprilat. Compared with enalapril and captopril, cilazapril is more potent and longer lasting.

Chemical Properties

White or almost white, crystalline powder.

Originator

Hoffmann-LaRoche (Switzerland)

Uses

Antihypertensive.

Definition

ChEBI: Cilazapril monohydrate is a hydrate that is the monohydrate of cilazapril. It is used for the treatment of hypertension and heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It contains a cilazapril.

brand name

Inhibace (Hoffmann-LaRoche).

CILAZAPRIL Preparation Products And Raw materials

Raw materials

Preparation Products

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CILAZAPRIL Suppliers

Chembest Research Laboratories Limited
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Haoyuan Chemexpress Co., Ltd.
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ChemStrong Scientific Co.,Ltd
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sales@chem-strong.com
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Guangzhou QiYun Biotechnology Co., Ltd.
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505721671@qq.com
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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Chengdu Dianchun Technology Co., Ltd
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Dideu Industries Group Limited
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AFINE CHEMICALS LIMITED
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Shaanxi Dideu Medichem Co. Ltd
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View Lastest Price from CILAZAPRIL manufacturers

Dideu Industries Group Limited
Product
CILAZAPRIL 92077-78-6
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-10
Shaanxi Dideu Medichem Co. Ltd
Product
Cilazapril 92077-78-6
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-09
Career Henan Chemical Co
Product
Cilazapril (monohydrate) 92077-78-6
Price
US $1.00/g
Min. Order
1g
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-10

92077-78-6, CILAZAPRILRelated Search:


  • Initiss
  • Justor
  • Vascase
  • 9[[1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]OCTAHYDRO-10-OXO-6HPYRIDAZINO[1,2-A][1,2]DIAZEPINE-1-CARBOXYLIC ACID
  • CILAZAPRIL EPC(
  • CILAZAPRIL EPC(CRM STANDARD)
  • CILAZAPRIL IMPURITY A1,1-DIMETHYLETHYL(1S,9S)-9-[[(S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]-10-OXO-OCTAHYDRO-6H-PYRIDAZINO[1,2A][1,2]DIAZEPINE-1-CABOXYLATE EPC
  • [1S-[1α,9α(R^<*>^)]]-9-[[1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-α][1,2]diazepine-1-carboxylic acid monohydrate
  • 9-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-10-oxo-1,2,3,4,6,7,8,9-oc tahydropyridazino[1,2-a]diazepine-1-carboxylic acid
  • Inhibace
  • Cilazapril Hydrate
  • Inhibace monohydrate
  • INHIBACE MONOHYDRATE;RO 31-2848 MONOHYDRATE;VASCACE MONOHYDRATE
  • Vascace monohydrate
  • (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]aMino}-1-hydroxy-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
  • Cilazapril Monohydrate (Inhibace)
  • 6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylicacid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]aMino]octahydro-10-oxo-,hydrate (1:1), (1S,9S)-
  • (1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, hydrate (1:1)
  • (1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate
  • (1S,9S)-9-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate (1:1)
  • 6h-pyridazino(1,2-a)(1,2)diazepine-1-carboxylicacid,octahydro-9-((1-(ethoxyca
  • cilazaprilmonohydrate
  • hydrate,(1s-(1-alpha,9-alpha(r*)))-rbonyl)-3-phenylpropyl)amino)-10-oxo
  • ro31-2848monohydrate
  • (1s,9s)-9-[(s)-1-ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
  • Cilazapril CRS
  • (1S,9S)-9-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-10-oxooctahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
  • Cilazapril Monohydrate (Ro 31-2848)
  • (1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-10-oxooctahydro-6h-pyridazino[1,2-a][1,2]diazepine-1-carboxylicacidmonohydrate
  • Dynorm
  • 92077-78-6
  • C22H31N3O5H2O
  • Inhibitors