CILAZAPRIL

Product Name: CILAZAPRIL
CAS No.: 92077-78-6
Chemical Name: CILAZAPRIL
Synonyms: Justor;Dynorm;Vascase;Initiss;Inhibace;Cilazapril CRS;CILAZAPRIL EPC(;Cilazapril Hydrate;Vascace monohydrate;Inhibace monohydrate
CBNumber: CB4771690
Molecular Formula: C22H33N3O6
Formula Weight: 435.51
MOL File: 92077-78-6.mol

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CILAZAPRIL Property

Melting point:: 98° (dec)
alpha: D20 -62.51° (c = 1% in ethanol)
storage temp.: Store at -20°C
solubility: Slightly soluble in water, freely soluble in methanol and in methylene chloride.
pka: pKa1 3.3; pKa2 6.4(at 25℃)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C2174000
Product name: Cilazapril
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: c2174000
Price: $153
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FC34997
Product name: Cilazapril monohydrate
Packaging: 25mg
Price: $185
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC34997
Product name: Cilazapril monohydrate
Packaging: 10mg
Price: $95
Updated: 2021/12/16

ChemScene

Product number: CS-2448
Product name: Cilazaprilmonohydrate
Purity: 99.44%
Packaging: 10mg
Price: $108
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC34997
Product name: Cilazapril monohydrate
Packaging: 5mg
Price: $60
Updated: 2021/12/16

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CILAZAPRIL Chemical Properties,Usage,Production

Description

Cilazapril is a new ACE inhibitor useful in the management of mild to moderate hypertension. Orally administered cilazapril is a prodrug which is de-esterified to its active diacid metabolite cilazprilat. Compared with enalapril and captopril, cilazapril is more potent and longer lasting.

Chemical Properties

White or almost white, crystalline powder.

Originator

Hoffmann-LaRoche (Switzerland)

Uses

Antihypertensive.

Definition

ChEBI: Cilazapril monohydrate is a hydrate that is the monohydrate of cilazapril. It is used for the treatment of hypertension and heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It contains a cilazapril.

brand name

Inhibace (Hoffmann-LaRoche).

CILAZAPRIL Preparation Products And Raw materials

Raw materials

Lithium tert-butoxide Potassium bicarbonate Diborane Sodium carbonate

Preparation Products

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CILAZAPRIL Suppliers

Canada 2 China 41 France 1 India 3 United Kingdom 1 United States 17 Global 65

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View Lastest Price from CILAZAPRIL manufacturers

Dideu Industries Group Limited

Product: CILAZAPRIL 92077-78-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-10

Shaanxi Dideu Medichem Co. Ltd

Product: Cilazapril 92077-78-6
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-09

Career Henan Chemical Co

Product: Cilazapril (monohydrate) 92077-78-6
Price: US $1.00/g
Min. Order: 1g
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-10

92077-78-6, CILAZAPRILRelated Search:

Cefaclor Quinapril hydrochloride Chlorprothixene ENALAPRILAT DIHYDRATE Lopinavir Ramipril Cilazapril

Initiss

Justor

Vascase

9[[1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]OCTAHYDRO-10-OXO-6HPYRIDAZINO[1,2-A][1,2]DIAZEPINE-1-CARBOXYLIC ACID

CILAZAPRIL EPC(

CILAZAPRIL EPC(CRM STANDARD)

CILAZAPRIL IMPURITY A1,1-DIMETHYLETHYL(1S,9S)-9-[[(S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]-10-OXO-OCTAHYDRO-6H-PYRIDAZINO[1,2A][1,2]DIAZEPINE-1-CABOXYLATE EPC

[1S-[1α，9α(R^<*>^)]]-9-[[1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1，2-α][1，2]diazepine-1-carboxylic acid monohydrate

9-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-10-oxo-1,2,3,4,6,7,8,9-oc tahydropyridazino[1,2-a]diazepine-1-carboxylic acid

Inhibace

Cilazapril Hydrate

Inhibace monohydrate

INHIBACE MONOHYDRATE;RO 31-2848 MONOHYDRATE;VASCACE MONOHYDRATE

Vascace monohydrate

(1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]aMino}-1-hydroxy-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid

Cilazapril Monohydrate (Inhibace)

6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylicacid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]aMino]octahydro-10-oxo-,hydrate (1:1), (1S,9S)-

(1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, hydrate (1:1)

(1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate

(1S,9S)-9-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate (1:1)

6h-pyridazino(1,2-a)(1,2)diazepine-1-carboxylicacid,octahydro-9-((1-(ethoxyca

cilazaprilmonohydrate

hydrate,(1s-(1-alpha,9-alpha(r*)))-rbonyl)-3-phenylpropyl)amino)-10-oxo

ro31-2848monohydrate

(1s,9s)-9-[(s)-1-ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid

Cilazapril CRS

(1S,9S)-9-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-10-oxooctahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid

Cilazapril Monohydrate (Ro 31-2848)

(1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-10-oxooctahydro-6h-pyridazino[1,2-a][1,2]diazepine-1-carboxylicacidmonohydrate

Dynorm

92077-78-6

C22H31N3O5H2O

Inhibitors