ChemicalBook > CAS DataBase List > 2-Chloro-4,6-dimethoxy-1,3,5-triazine

2-Chloro-4,6-dimethoxy-1,3,5-triazine

Product Name
2-Chloro-4,6-dimethoxy-1,3,5-triazine
CAS No.
3140-73-6
Chemical Name
2-Chloro-4,6-dimethoxy-1,3,5-triazine
Synonyms
CDMT;AKOS 89995;CDMT 2-Chloro-4,6-diMethoxy-1,3,5-triazine;Chlorodimethoxytriazine;NSC 46520;6-diMethoxy-1;5-triazine (CDMT);2-Chloro-4,6-dimetho;2-Chloro-4,6-dimethoxy-1;2-CHLORO-4,6-DIMETHOXY-TRIAZINE
CBNumber
CB4775597
Molecular Formula
C5H6ClN3O2
Formula Weight
175.57
MOL File
3140-73-6.mol
More
Less

2-Chloro-4,6-dimethoxy-1,3,5-triazine Property

Melting point:
71-74 °C (lit.)
Boiling point:
99-100 °C (1 mmHg)
Density 
1.7917 (rough estimate)
vapor pressure 
5.8Pa at 25℃
refractive index 
1.5870 (estimate)
Flash point:
99-100°C/1mm
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform, Methanol
form 
Crystalline Powder
pka
0.33±0.10(Predicted)
color 
White to almost white
Water Solubility 
insoluble
BRN 
148988
InChIKey
GPIQOFWTZXXOOV-UHFFFAOYSA-N
LogP
2.105 at 25℃
CAS DataBase Reference
3140-73-6(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37-36
RIDADR 
UN3077
WGK Germany 
3
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
375217
Product name
2-Chloro-4,6-dimethoxy-1,3,5-triazine
Purity
97%
Packaging
5g
Price
$63.7
Updated
2024/03/01
TCI Chemical
Product number
C1676
Product name
2-Chloro-4,6-dimethoxy-1,3,5-triazine
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
C1676
Product name
2-Chloro-4,6-dimethoxy-1,3,5-triazine
Purity
>97.0%(HPLC)(T)
Packaging
25g
Price
$39
Updated
2024/03/01
Alfa Aesar
Product number
B24474
Product name
2-Chloro-4,6-dimethoxy-1,3,5-triazine, 98%
Packaging
5g
Price
$43.65
Updated
2024/03/01
Alfa Aesar
Product number
B24474
Product name
2-Chloro-4,6-dimethoxy-1,3,5-triazine, 98%
Packaging
25g
Price
$126
Updated
2024/03/01
More
Less

2-Chloro-4,6-dimethoxy-1,3,5-triazine Chemical Properties,Usage,Production

Chemical Properties

white to almost white crystalline powder

Uses

2-Chloro-4,6-dimethoxy-1,3,5-triazine is used as a peptide coupling agent for the purification of peptides. It is used in the synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride through coupling with N-methylmorpholine in tetrahydrofuran. Further, it plays an important role in the production of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, through reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine. In addition to this, it is involved in the preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts through reaction with various tertiary amines.

Uses

2-Chloro-4,6-dimethoxy-1,3,5-triazine may be used in the following studies:

  • The specific labeling of streptavidin by the modular method for affinity labeling (MoAL).
  • The preparation of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, via reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine.
  • The preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts, via reaction with various tertiary amines.
  • The synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, via coupling with N-methylmorpholine in THF.

General Description

2-Chloro-4,6-dimethoxy-1,3,5-triazine is a stable, yet highly reactive, peptide coupling agent. It is reported as useful coupling reagent for the purification of peptides. Catalytic amide-forming reactions of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported. Procedure for the preparation of multikilogram quantities of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported.

Synthesis

A preparation method of 2-chloro-4,6-dimethoxy-1,3,5-triazine comprises the following steps: using cyanuric chloride and sodium methoxide solid as reaction raw materials and N, N-dimethylformamide as a reaction solvent, gradually heating to obtain a 2-chloro-4,6-dimethoxy-1,3,5-triazine crude product, and finally, recrystallizing with heptane for purification. The reaction temperature is controlled to prepare the product, and the yield is up to 91%.

2-Chloro-4,6-dimethoxy-1,3,5-triazine Preparation Products And Raw materials

Raw materials

Sodium bicarbonate Methanol PETROLEUM ETHER Cyanuric chloride

Preparation Products

More
Less

2-Chloro-4,6-dimethoxy-1,3,5-triazine Suppliers

Americas 1 Belgium 2 Canada 3 China 400 Europe 5 France 1 Germany 11 India 48 Ireland 1 Israel 1 Italy 2 Japan 3 Poland 1 Slovakia 1 South Korea 1 Switzerland 5 Ukraine 1 United Kingdom 24 United States 48 Global 559
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
AB PharmaTech,LLC
Tel
323-480-4688
Fax
323-480-4688
Email
sales@acrospharmatech.com
Country
United States
ProdList
989
Advantage
55
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Anisyn, Inc.
Tel
--
Fax
--
Email
sales@anisyn.com
Country
United States
ProdList
863
Advantage
0
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Chem-Impex International, Inc. (CII)
Tel
--
Fax
--
Email
Customer@chemimpex.com
Country
United States
ProdList
893
Advantage
58
Interchem Corporation USA
Tel
--
Fax
--
Email
esa@interchem.com
Country
United States
ProdList
469
Advantage
58
Alzchem, Llc
Tel
--
Fax
--
Country
United States
ProdList
47
Advantage
58
Advanced Chemical Intermediates Ltd.
Tel
--
Fax
--
Email
enquiries@acints.com
Country
United States
ProdList
4893
Advantage
58
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
RnD SciChem, LLC
Tel
--
Fax
--
Email
rndscichem@gmail.com
Country
United States
ProdList
569
Advantage
0
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
CNH Technologies, Inc.
Tel
--
Fax
--
Email
info@cnhtechnologies.com
Country
United States
ProdList
353
Advantage
42
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
Fluorous Technologies Inc.
Tel
--
Fax
--
Email
orders@fluorous.com
Country
United States
ProdList
192
Advantage
58
D & O PHARMACHEM INC.
Tel
--
Fax
--
Email
info@dochem.com
Country
United States
ProdList
202
Advantage
51
AnaSpec, Inc.
Tel
--
Fax
--
Email
service@anaspec.com
Country
United States
ProdList
4871
Advantage
77
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Davos Chemical Corporation
Tel
--
Fax
--
Email
info@davos.com
Country
United States
ProdList
1640
Advantage
65
AcceleDev Chemical LLC
Tel
--
Fax
--
Email
info@acceledev.com
Country
United States
ProdList
632
Advantage
42
BOSCHE SCIENTIFIC, LLC
Tel
--
Fax
--
Email
Sales@BoscheSci.com
Country
United States
ProdList
6477
Advantage
55
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
More
Less

View Lastest Price from 2-Chloro-4,6-dimethoxy-1,3,5-triazine manufacturers

Watson Biotechnology Co.,Ltd
Product
CDMT 2-Chloro-4,6-dimethoxy-1,3,5-triazine 3140-73-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20MT
Release date
2024-09-26
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Chloro-4,6-dimethoxy-1,3,5-triazine/CDMT 3140-73-6
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000 KG
Release date
2021-06-03
airuikechemical co., ltd.
Product
2-chloro-4,6-dimethoxy-1,3,5-triazine 3140-73-6
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-09

3140-73-6, 2-Chloro-4,6-dimethoxy-1,3,5-triazineRelated Search:

Epichlorohydrin Dimethyldimethoxysilane 4-Methoxybenzylchloride 3-Chloropropyltrimethoxysilane Acetoxyacetyl chloride 1,3,5-Triazine Difluorochloromethane Chloroacetic acid F26 CDMT, 2-Chloro-4,6-bis(4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluorononyloxy)-1,3,5-triazine 2-Chloro-4,6-dimethoxy-1,3,5-triazine 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE (3140-73-6) 2-CHLORO-4-(2,4-DIFLUOROPHENOXY)-6-METHOXY-1,3,5-TRIAZINE BIS-RF8 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE 2-CHLORO-4-(2,4-DIMETHYLPHENOXY)-6-METHOXY-1,3,5-TRIAZINE BIS-RF6 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE 2-CHLORO-4-(4-CHLORO-3-METHYLPHENOXY)-6-METHOXY-1,3,5-TRIAZINE 2-CHLORO-4,6-DI(4-FLUOROPHENOXY)-1,3,5-TRIAZINE Dimethoxy

  • CDMT
  • AKOS 89995
  • 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE
  • 2-CHLORO-4,6-DIMETHOXY-TRIAZINE
  • Chlorodimethoxytriazine
  • 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE, 9 7%
  • 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE (CDMT)
  • 2-Chloro-4,6-dimethoxy-1
  • oro-4,6-dimethoxy-1,3,5-triazine
  • 1,3,5-Triazine, 2-chloro-4,6-dimethoxy-
  • 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE 98%
  • 2,4-Dimethoxy-6-chloro-1,3,5-triazine
  • 2,4-Dimethoxy-6-chloro-s-triazine
  • 4,6-Dimethoxy-2-chloro-1,3,5-triazine
  • 2-Chloro-4,6-dimetho
  • 5-triazine (CDMT)
  • 6-diMethoxy-1
  • 2-CHLORO 4,6-DIMETHOX 1,3,5-TRIAZINE
  • 4-CHLORO-2,6-DIMETHOXY-1,3.5-TRIAZINE
  • CDMT 2-Chloro-4,6-diMethoxy-1,3,5-triazine
  • 4,6-DiMethoxy-2-chloro-s-triazine
  • NSC 46520
  • 2-Chloro-4,6-diMethoxy-1,3,5-triazine, 98% 25GR
  • 2-Chloro-4,6-diMethoxy-1,3,5-triazine, 98% 5GR
  • 2-Chloro-4,6-dimethoxy-s-triazine
  • 2-chloro -4,6-twoMethoxy -1,3,5-three work
  • 2-Chlor-4,6-dimethoxy-1,3,5-triazin
  • 2-Chloro-4,6-dimethoxy-1,3,5-triazine&gt
  • 2-Chloro-4,6-dimethoxy-1,3,5-triazine, 97%, for synthesis
  • 2-Chloro-4,6 Dimethoxy-1,3,5 Triazine extrapure, 99%
  • 3140-73-6
  • C5H6C1N3O2
  • C5H6ClN3O2
  • HETERO CHLORIDE
  • Building Blocks
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Triazines
  • Miscellaneous
  • Aromatics
  • Heterocycles
  • Miscellaneous Reagents
  • Biochemistry
  • Coupling Reactions (Peptide Synthesis)
  • Peptide Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Triazines
  • TriazinesBuilding Blocks
  • Starting Raw Materials & Intermediates
  • bc0001