ChemicalBook > CAS DataBase List > Olinvacimab
Olinvacimab
- Product Name
- Olinvacimab
- CAS No.
- 2095504-49-5
- Chemical Name
- Olinvacimab
- Synonyms
- Tanibirumab;Olinvacimab;Olinvacimab (anti-VEGFR2);Research Grade Tanibirumab;Research Grade Olinvacimab;Research Grade Tanibirumab (DHE16604);Research Grade Olinvacimab (DHE16602)
- CBNumber
- CB48081094
- Formula Weight
- 0
- MOL File
- Mol file
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Olinvacimab Property
- form
- Liquid
- color
- Colorless to light yellow
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Olinvacimab Chemical Properties,Usage,Production
Uses
Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer[1].
in vivo
Olinvacimab (100 ng; s.c., once) inhibits angiogenesis in vivo[1].
| Animal Model: | Matrigel-implanted nude mice model[1] |
| Dosage: | 100 ng |
| Administration: | Subcutaneous injection; 100 ng, once |
| Result: | Inhibited the neovascularization induced by hVEGF165. |
References
[1] Lee WS, et al. TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis. MAbs. 2015;7(5):957-68. DOI:10.1080/19420862.2015.1045168
Olinvacimab Preparation Products And Raw materials
Raw materials
Preparation Products
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Olinvacimab Suppliers
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