3-FLUORO-4-NITRO-BENZALDEHYDE

Product Name: 3-FLUORO-4-NITRO-BENZALDEHYDE
CAS No.: 160538-51-2
Chemical Name: 3-FLUORO-4-NITRO-BENZALDEHYDE
Synonyms: uoro-4-nitrobenzenecarbaL;3-floro-4-nitrobenzaldehyde;2-Fluoro-4-formylnitrobenzene;3-FLUORO-4-NITRO-BENZALDEHYDE;Benzaldehyde, 3-fluoro-4-nitro-;8-(Trifluoromethyl)propiophenone;3-Fluoro-4-nitrobenzaldehyde 98%;3-FLUORO-4-NITROBENZENECARBALDEHYDE
CBNumber: CB4836142
Molecular Formula: C7H4FNO3
Formula Weight: 169.11
MOL File: 160538-51-2.mol

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3-FLUORO-4-NITRO-BENZALDEHYDE Property

Melting point:: 57-58
Boiling point:: 312℃
Density: 1.443
Flash point:: 143℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to crystal
color: Light yellow to Amber
InChI: InChI=1S/C7H4FNO3/c8-6-3-5(4-10)1-2-7(6)9(11)12/h1-4H
InChIKey: BWUIGISQVCIQBT-UHFFFAOYSA-N
SMILES: C(=O)C1=CC=C([N+]([O-])=O)C(F)=C1

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2913000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: F1130
Product name: 3-Fluoro-4-nitrobenzaldehyde
Purity: >97.0%(GC)
Packaging: 1g
Price: $83
Updated: 2025/07/31

TCI Chemical

Product number: F1130
Product name: 3-Fluoro-4-nitrobenzaldehyde
Purity: >97.0%(GC)
Packaging: 5g
Price: $326
Updated: 2025/07/31

TRC

Product number: F401538
Product name: 3-Fluoro-4-nitrobenzaldehyde
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Apolloscientific

Product number: PC7624
Product name: 3-Fluoro-4-nitrobenzaldehyde
Purity: 98%
Packaging: 250mg
Price: $22
Updated: 2021/12/16

Matrix Scientific

Product number: 047023
Product name: 3-Fluoro-4-nitrobenzenecarbaldehyde
Purity: >95%
Packaging: 500mg
Price: $26
Updated: 2021/12/16

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3-FLUORO-4-NITRO-BENZALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

3-fluoro-4-nitrobenzaldehyde is a strong, oxidizing agent with a pungent odor that is soluble in organic solvents.

Uses

3-fluoro-4-nitrobenzaldehyde is resistant to oxidation by acids and bases and can be used for the synthesis of cytomegalovirus (CMV) inhibitors.

Synthesis

863604-64-2

160538-51-2

General procedure for the synthesis of 3-fluoro-4-nitrobenzaldehyde from 3-fluoro-N-methoxy-N-methyl-4-nitrobenzamide: 3-fluoro-N-methoxy-N-methyl-4-nitrobenzamide was added to 800 mL of tetrahydrofuran (THF) under ice-salt/water bath cooling conditions. Subsequently, a THF solution of 1 M diisobutylaluminum hydride (DIBAL) was slowly added through the addition funnel over 30 min. The reaction mixture was stirred under nitrogen (N2) protection for 1 hour. Upon completion of the reaction, the reaction mixture was carefully diluted with 1N hydrochloric acid (500 mL) and ethyl acetate (EtOAc, 500 mL) and then transferred to a separatory funnel for separation. The organic phase was washed sequentially with 1N hydrochloric acid (3 × 250 mL), 1N sodium hydroxide (2 × 250 mL) and water (250 mL). All aqueous layers were back-extracted with ethyl acetate (2 × 250 mL). The organic layers were combined, dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated in vacuum to give 67 g of the target product 3-fluoro-4-nitrobenzaldehyde (396 mmol, 88% yield). The product was confirmed by nuclear magnetic resonance hydrogen spectroscopy (1H-NMR, DMSO-d6): δ 10.06 (s, 1H), 8.36-8.32 (t, J = 7.8 Hz, 1H), 8.06-8.03 (d, J = 11.2 Hz, 1H), 7.95-7.93 (d, J = 9.1 Hz, 1H).

References

[1] Patent: WO2005/121147, 2005, A1. Location in patent: Page/Page column 106

3-FLUORO-4-NITRO-BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-FLUORO-4-NITRO-BENZALDEHYDE Suppliers

Americas 1 China 120 Europe 1 France 1 Germany 3 India 5 Japan 1 Switzerland 1 United Kingdom 6 United States 27 Global 166

Changzhou Pumelo Co.,Ltd.

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Energy Chemical

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Wuhan Chemwish Technology Co., Ltd

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Shanghai Harvest Chemical Industrial Co., Ltd.

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View Lastest Price from 3-FLUORO-4-NITRO-BENZALDEHYDE manufacturers

Career Henan Chemical Co

Product: 3-FLUORO-4-NITRO-BENZALDEHYDE 160538-51-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-24

160538-51-2, 3-FLUORO-4-NITRO-BENZALDEHYDERelated Search:

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3-FLUORO-4-NITRO-BENZALDEHYDE

3-FLUORO-4-NITROBENZENECARBALDEHYDE

3-floro-4-nitrobenzaldehyde

2-Fluoro-4-formylnitrobenzene

3-Fluoro-4-nitrobenzaldehyde 98%

Benzaldehyde, 3-fluoro-4-nitro-

uoro-4-nitrobenzenecarbaL

8-(Trifluoromethyl)propiophenone

160538-51-2

Fluorine series