Meptazinol hydrochloride

ChemicalBook > CAS DataBase List > Meptazinol hydrochloride

Meptazinol hydrochloride

Product Name: Meptazinol hydrochloride
CAS No.: 59263-76-2
Chemical Name: Meptazinol hydrochloride
Synonyms: Meptazinol hcl;Meptazinol-d3 HCl;Meptazinol hydrochlo;WY-22811 hydrochloride;IL-22811 hydrochloride;MEPTAZINOL HYDROCHLORIDE;Meptazinol-d3 hydrochloride;Meptazinol hydrochloride USP/EP/BP;IL-22811 HYDROCHLORIDE;WY-22811 HYDROCHLORIDE;3-(3-ethyl-1-methyl-3-azepanyl)phenol hydrochloride
CBNumber: CB4843649
Molecular Formula: C15H24ClNO
Formula Weight: 269.81
MOL File: 59263-76-2.mol

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Meptazinol hydrochloride Property

Melting point:: 250-252°C
storage temp.: Inert atmosphere,2-8°C
solubility: H2O: >10mg/mL
form: powder
color: white to off-white
Stability:: Hygroscopic
InChIKey: MPJUSISYVXABBH-UHFFFAOYSA-N

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 1
RTECS: SL4250000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M2824
Product name: Meptazinol hydrochloride
Packaging: 10mg
Price: $91.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: BP583
Product name: Meptazinol hydrochloride
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 100MG
Price: $229
Updated: 2024/03/01

Sigma-Aldrich

Product number: M2824
Product name: Meptazinol hydrochloride
Packaging: 50mg
Price: $314
Updated: 2022/05/15

Tocris

Product number: 3636
Product name: Meptazinol hydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $331
Updated: 2021/12/16

Tocris

Product number: 3636
Product name: Meptazinol hydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $83
Updated: 2021/12/16

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Meptazinol hydrochloride Chemical Properties,Usage,Production

Description

Meptazinol hydrochloride is an injectable narcotic analgesic with antagonist properties; it is similar in potency to meperidine. Meptazinol appears to have a low propensity toward respiratory depression and other opiate-like side effects, possibly due to selective interaction with the mu-1 receptor. Also somewhat unique for an analgesic, it interacts with central cholinergic receptors. An oral form of meptazinol is under development.

Chemical Properties

White Solid

Originator

Wyeth (United Kingdom)

Uses

Analgesic;Opiate receptor agonist

Uses

Mixed opioid agonist-antagonist. Analgesic (narcotic).

brand name

MEPTID

Biological Activity

Centrally active opioid analgesic. Partial agonist at the μ 1 opioid receptor. Also shown to inhibit acetylcholinesterase.

Biochem/physiol Actions

Meptazinol entered the human pharmaceutical market as a racemic mixture in the 1980s for use as an analgesic. Its pharmacology is not completely understood; however, its analgesic properties are mostly due to its partial agonism at the mu1 opioid receptor. Due to its partial agonism, Meptazinol antagonizes morphine dependence in vivo. Its advantage over other opiates is its reduced capacity to cause addition and respiratory depression, also due to its intrinsic activity as a partial agonist. Meptazinol has been found to have additional activity as an acetylcholinesterase (AChE) inhibitor, particularly in its (-) enantiomeric form, which may partially explain its analgesic properties. AChE inhibitors are used to treat Alzheimer′s disease, providing additional interest in this compound.

Meptazinol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Meptazinol hydrochloride manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Meptazinol Hydrochloride 59263-76-2
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 50kg/Month
Release date: 2024-09-12

Xiamen Wonderful Bio Technology Co., Ltd.

Product: Meptazinol HCl 59263-76-2
Price: US $120.00/KG
Min. Order: 1250KG
Purity: 99.8%
Supply Ability: 330T
Release date: 2023-06-05

Dideu Industries Group Limited

Product: Meptazinol hydrochloride 59263-76-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-16

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Intermediates & Fine Chemicals

Pharmaceuticals

59263-76-2