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Meptazinol hydrochloride

Product Name
Meptazinol hydrochloride
CAS No.
59263-76-2
Chemical Name
Meptazinol hydrochloride
Synonyms
Meptazinol hcl;Meptazinol-d3 HCl;Meptazinol hydrochlo;WY-22811 hydrochloride;IL-22811 hydrochloride;MEPTAZINOL HYDROCHLORIDE;Meptazinol-d3 hydrochloride;Meptazinol hydrochloride USP/EP/BP;IL-22811 HYDROCHLORIDE;WY-22811 HYDROCHLORIDE;3-(3-ethyl-1-methyl-3-azepanyl)phenol hydrochloride
CBNumber
CB4843649
Molecular Formula
C15H24ClNO
Formula Weight
269.81
MOL File
59263-76-2.mol
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Meptazinol hydrochloride Property

Melting point:
250-252°C
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: >10mg/mL
form 
powder
color 
white to off-white
Stability:
Hygroscopic
InChIKey
MPJUSISYVXABBH-UHFFFAOYSA-N
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
1
RTECS 
SL4250000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M2824
Product name
Meptazinol hydrochloride
Packaging
10mg
Price
$91.6
Updated
2024/03/01
Sigma-Aldrich
Product number
BP583
Product name
Meptazinol hydrochloride
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$229
Updated
2024/03/01
Sigma-Aldrich
Product number
M2824
Product name
Meptazinol hydrochloride
Packaging
50mg
Price
$314
Updated
2022/05/15
Tocris
Product number
3636
Product name
Meptazinol hydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$331
Updated
2021/12/16
Tocris
Product number
3636
Product name
Meptazinol hydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$83
Updated
2021/12/16
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Meptazinol hydrochloride Chemical Properties,Usage,Production

Description

Meptazinol hydrochloride is an injectable narcotic analgesic with antagonist properties; it is similar in potency to meperidine. Meptazinol appears to have a low propensity toward respiratory depression and other opiate-like side effects, possibly due to selective interaction with the mu-1 receptor. Also somewhat unique for an analgesic, it interacts with central cholinergic receptors. An oral form of meptazinol is under development.

Chemical Properties

White Solid

Originator

Wyeth (United Kingdom)

Uses

Analgesic;Opiate receptor agonist

Uses

Mixed opioid agonist-antagonist. Analgesic (narcotic).

brand name

MEPTID

Biological Activity

Centrally active opioid analgesic. Partial agonist at the μ 1 opioid receptor. Also shown to inhibit acetylcholinesterase.

Biochem/physiol Actions

Meptazinol entered the human pharmaceutical market as a racemic mixture in the 1980s for use as an analgesic. Its pharmacology is not completely understood; however, its analgesic properties are mostly due to its partial agonism at the mu1 opioid receptor. Due to its partial agonism, Meptazinol antagonizes morphine dependence in vivo. Its advantage over other opiates is its reduced capacity to cause addition and respiratory depression, also due to its intrinsic activity as a partial agonist. Meptazinol has been found to have additional activity as an acetylcholinesterase (AChE) inhibitor, particularly in its (-) enantiomeric form, which may partially explain its analgesic properties. AChE inhibitors are used to treat Alzheimer′s disease, providing additional interest in this compound.

Meptazinol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Meptazinol hydrochloride Suppliers

Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from Meptazinol hydrochloride manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Meptazinol Hydrochloride 59263-76-2
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
50kg/Month
Release date
2024-09-12
Xiamen Wonderful Bio Technology Co., Ltd.
Product
Meptazinol HCl 59263-76-2
Price
US $120.00/KG
Min. Order
1250KG
Purity
99.8%
Supply Ability
330T
Release date
2023-06-05
Dideu Industries Group Limited
Product
Meptazinol hydrochloride 59263-76-2
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-16

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