Penicillin G potassium salt

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Penicillin G potassium salt

Product Name: Penicillin G potassium salt
CAS No.: 113-98-4
Chemical Name: Penicillin G potassium salt
Synonyms: PENICILLIN G POTASSIUM;BENZYLPENICILLIN POTASSIUM;PENICILLIN G POTASSIUM SALT;PENICILLIN G POTASSIUM SALT;pfizerpen;Penicilline G;potassium [2s-(2alpha,5alpha,6beta)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;Pen-G;forpen;PENICILLINE G POTASSIUM
CBNumber: CB4855484
Molecular Formula: C16H17KN2O4S
Formula Weight: 372.48
MOL File: 113-98-4.mol

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Penicillin G potassium salt Property

Melting point:: 214-217 C
alpha: D22 +285° (c = 0.748 in water)
refractive index: 294 ° (C=1, H2O)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: H₂O: 100 mg/mL
form: powder
color: Needles from butanol (aq)
PH: pH (10g/L, 25℃) : 5.0～7.5
Water Solubility: Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.
Merck: 14,7094
BRN: 3832841
Stability:: Hygroscopic
InChIKey: IYNDLOXRXUOGIU-LQDWTQKMSA-M
SMILES: N12C([C@@H](NC(=O)CC3=CC=CC=C3)[C@@]1([H])SC(C)(C)[C@@H]2C([O-])=O)=O.[K+] |&1:2,13,19,r|
EPA Substance Registry System: Penicillin G Potassium (113-98-4)

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Safety

Hazard Codes: Xn,C,F
Risk Statements: 42/43-34-11
Safety Statements: 36/37-45-36/37/39-26-16-60-37-24-22
WGK Germany: 2
RTECS: XH9700000
F: 10-23
TSCA: Yes
HS Code: 29411000
Toxicity: LD50 oral in rabbit: 5848mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PENK
Product name: Penicillin G potassium salt
Purity: ~1600?U/mg
Packaging: 1000000units
Price: $21.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: PENK
Product name: Penicillin G potassium salt
Purity: ~1600?U/mg
Packaging: 10000000units
Price: $27.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR2640
Product name: Penicillin G Potassium
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 500MG
Price: $200
Updated: 2024/03/01

Sigma-Aldrich

Product number: PENK
Product name: Penicillin G potassium salt
Purity: ~1600?U/mg
Packaging: 100000000units
Price: $130
Updated: 2024/03/01

Sigma-Aldrich

Product number: P7794
Product name: Penicillin G potassium salt
Purity: powder, BioReagent, suitable for cell culture
Packaging: 1000000units
Price: $22.5
Updated: 2024/03/01

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Penicillin G potassium salt Chemical Properties,Usage,Production

Description

Benzylpenicillin potassiumwas the first crystalline penicillin produced on an industrial scale , . It is produced in the pure state by the addition of phenylacetate to a culture of Penicillium chrysogenum. The crystalline benzylpenicillin potassium contains 1598 U/mg.

Chemical Properties

Penicillin G potassium salt is also known as Potassium benzylpenicillin, it is white crystalline powder, odorless or slightly specific odor, hygroscopic. Soluble in water, physiological saline, glucose solution. The aqueous solution of it is easy to fail when placed at room temperature, and it will fail rapidly in the presence of acid, alkali, oxidant, etc. Penicillin G potassium salt has good antibacterial effect on Streptococcus such as Streptococcus hemolyticus, Streptococcus pneumoniae and Staphylococcus without penicillinase.

Uses

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

Preparation

Penicillin G potassium salt is a highly effective and low toxicity antibiotic, which is obtained by salt formation of Chlorpheniramine maleate and maleic acid.

Definition

ChEBI: Penicillin G potassium salt is organic potassium salt of benzylpenicillin. It is an antibiotic substance produced by Penicillium sp. Antibacterial. It contains a benzylpenicillin(1-).

brand name

Pentids (Apothecon); Pfizerpen (Pfizer).

General Description

Penicillin G Potassium is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic. Penicillin G potassium binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, which is a critical component of the bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently leading to bacterial cell growth inhibition and cell lysis.

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.
Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Safety Profile

Poison by intracerebral andintravenous routes. Moderately toxic by intraperitonealroute. Mutation data reported. See other penicillin entries.When heated to decomposition it emits toxic fumes ofNOx and SOx.

Penicillin G potassium salt Preparation Products And Raw materials

Raw materials

D(+)-Glucose Ethanol Potassium carbonate Butyl acetate 1-Butanol Phenylacetic acid

Preparation Products

Calcium gluconate Procaine penicillin G Cephalexin 6-Aminopenicillanic acid D-Penicillamine Pivaloyloxymethyl6-(phenylacetamido)penicillanate Penicillin G sodium salt

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View Lastest Price from Penicillin G potassium salt manufacturers

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Penicillin G potassium salt 113-98-4
Price: US $0.00/bou
Min. Order: 40bou
Purity: ≥96%
Supply Ability: 10000bou
Release date: 2024-04-22

Hebei Yime New Material Technology Co., Ltd.

Product: benzylpenicillin potassium 113-98-4
Price: US $20.00/KG
Min. Order: 25KG
Purity: 99%
Supply Ability: 1000KG/day
Release date: 2024-02-28

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Potassium Benzylpenicillin 113-98-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-04-24

113-98-4, Penicillin G potassium saltRelated Search:

Sodium 1-heptanesulfonate Potassium iodide Heptane Potassium Acetate Potassium chloride Potassium sorbate Potassium persulfate Potassium Citrate Potassium bromate PENITREM A D-Penicillamine Penicillin G sodium salt Carbenicillin Disodium Salt Potassium nitrate Potassium Penicillin G PHENETHICILLIN POTASSIUM SALT AMOXYCILLIN SODIUM/POTASSIUM CLAVULANATE Benzylpenicillin Potassium

tabilin

PENICILLIN G K-SALT

PENICILLIN G POTASSIUM SALT

PENICILLIN G POTASSIUM

potassium [2s-(2alpha,5alpha,6beta)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

potassium benzylpenicillin

4-Thia-1-azabicyclo

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, [2S-(2alpha,5alpha,6beta)]-, monopotassium salt

Dixocillin

Liquapen

M-cillin

Megacillin

Monopotassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1 -azabicyclo

Novopen-G

Orpeneed

Pen-G

BENZYLPENICILLIN POTASSIUM SALT

BENZYLPENICILLIN POTASSIUM

BENZYLPENICILLIN, K

falapen

forpen

hipercilina

hyasorb

hylenta

megacillintablets

monopen

monopotassiumsalt

notaral

novocillinvet.

pentid

pentids

pfizerpen

potassiumbenzylpenicillinate

potassiumbenzylpenicilling

potassiumpenicilling

potassiumsaltofbenzylpenicillin

qidpeng

scotcil

sk-penicilling

sugracillin

R-Pen

Truxcillin

Unilab Penicillin G

PENICILLINE G POTASSIUM

PENCILLINE G POTASSIUM

PENICILLIN G POTASSIIUM CRUDE OR FIRST CRYSTAL

PENICILLINE G POTASSIUM SALT VETR

PENICILLIN-G POTASSIUM CELL CULTURE*TEST ED

PENICILLIN G POTASSIUM USP

PENICILLIN G POTASSIUM PLANT CELL*CULTUR E TESTED

PENICILLIN-G POTASSIUM EMBRYO TESTED

PENICILLIN G POTASSIUM USP(CRM STANDARD)

PENICILLIN G POTASSIUM SALT CELL CULTURE REAGENT

BENZYLPENICILLIN POTASSIUM EPB(CRM STANDARD)

BENZYLPENICILLIN POTASSIUM SALT (PENICILLIN G POTASSIUM SALT)

BENZYLPENICILLIN POTASSIUM WHO(CRM STANDARD)

= 97% PURE WITH HPLC RADIOCHROMATOGRAM

BENZYLPENICILLIN POTASSIUM, [ACETAMIDO-1,2-14C]- 50-60 MCI(1.85-2.22 GBQ)/MMOL, HPLC PURIFIED, DELIVERED &gt