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simfibrate

Product Name
simfibrate
CAS No.
14929-11-4
Chemical Name
simfibrate
Synonyms
CLY-503;Sinfibrate;simfibrate;Cholesolvin;simfibrate USP/EP/BP;1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate];Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate);Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl;Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester;3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate
CBNumber
CB4875031
Molecular Formula
C23H26Cl2O6
Formula Weight
469.35
MOL File
14929-11-4.mol
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simfibrate Property

Melting point:
51-53°
Boiling point:
bp0.03 197-200°; bp0.15 220-230°
Density 
1.2623 (estimate)
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Safety

Toxicity
LD50 in mice, rats (g/kg): 3.3-3.5; 7.3-8.0 orally (Nakanishi, J. Pharm. Soc. Japan)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0004178
Product name
SIMFIBRATE
Purity
95.00%
Packaging
1G
Price
$1750
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004178
Product name
SIMFIBRATE
Purity
95.00%
Packaging
5G
Price
$7150
Updated
2021/12/16
Alichem
Product number
14929114
Product name
Propane-1,3-diylbis(2-(4-chlorophenoxy)-2-methylpropanoate)
Packaging
1g
Price
$1008
Updated
2021/12/16
Crysdot
Product number
CD12140008
Product name
Propane-1,3-diylbis(2-(4-chlorophenoxy)-2-methylpropanoate)
Purity
95+%
Packaging
1g
Price
$1186
Updated
2021/12/16
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simfibrate Chemical Properties,Usage,Production

Originator

Cholesorbin,Takeda,Japan,1971

Definition

ChEBI: Simfibrate is an organic molecular entity.

Manufacturing Process

A mixture of 22 grams of α-(p-chlorophenoxy)isobutyric acid, 3.8 grams of 1,3-propanediol, 0.5 gram of p-toluenesulfonic acid and 150 ml of xylene was refluxed. When the theoretically calculated amount of water had been removed, the xylene solution was washed with dilute aqueous sodium bicarbonate and then the xylene was distilled off. The residue was distilled under reduced pressure to give 11 grams (47% yield) of 1,3-propanediol bis[α-(p-chlorophenoxy)isobutyrate] boiling at 197° to 200°C/0.03 mm Hg.

Therapeutic Function

Antihyperlipidemic

simfibrate Preparation Products And Raw materials

Raw materials

Preparation Products

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simfibrate Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19881
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Fine Chem Trading LTD
Tel
--
Fax
--
Email
chemfinder@chemfinder.co.uk
Country
United States
ProdList
1609
Advantage
64

14929-11-4, simfibrateRelated Search:


  • simfibrate
  • 1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate]
  • Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl
  • Cholesolvin
  • CLY-503
  • Sinfibrate
  • Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate)
  • Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester
  • simfibrate USP/EP/BP
  • 3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate
  • 14929-11-4
  • C23H26Cl2O6