ChemicalBook > CAS DataBase List > 3-AMINO-5-BROMOBENZOIC ACID

3-AMINO-5-BROMOBENZOIC ACID

Product Name: 3-AMINO-5-BROMOBENZOIC ACID
CAS No.: 42237-85-4
Chemical Name: 3-AMINO-5-BROMOBENZOIC ACID
Synonyms: 3-Amino-6-bromobenzoic acid;Benzoicacid,3-aMino-5-broMo-;3-AMINO-5-BROMOBENZOIC ACID USP/EP/BP
CBNumber: CB4972327
Molecular Formula: C7H6BrNO2
Formula Weight: 216.03
MOL File: 42237-85-4.mol

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3-AMINO-5-BROMOBENZOIC ACID Property

Melting point:: 217-221 °C
Boiling point:: 398.3±32.0 °C(Predicted)
Density: 1.793
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: solid
pka: 3.97±0.10(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C7H6BrNO2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,9H2,(H,10,11)
InChIKey: RQSXRGSPGHZKFT-UHFFFAOYSA-N
SMILES: C(O)(=O)C1=CC(Br)=CC(N)=C1

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Safety

Hazard Codes: Xn
Risk Statements: 22
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2922498590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 686425
Product name: 3-Amino-5-bromobenzoic acid
Purity: 97%
Packaging: 5g
Price: $210
Updated: 2025/07/31

TRC

Product number: A602473
Product name: 3-Amino-5-bromobenzoic acid
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Matrix Scientific

Product number: 127738
Product name: 3-Amino-5-bromobenzoic acid
Purity: >95%
Packaging: 1g
Price: $59
Updated: 2021/12/16

ChemScene

Product number: CS-W002536
Product name: 3-Amino-5-bromobenzoic acid
Purity: 98.64%
Packaging: 25g
Price: $79
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA55299
Product name: 3-Amino-5-bromobenzoic acid
Packaging: 10g
Price: $85
Updated: 2021/12/16

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3-AMINO-5-BROMOBENZOIC ACID Chemical Properties,Usage,Production

Uses

peptide synthesis

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

6307-83-1

42237-85-4

The general procedure for the synthesis of 3-amino-5-bromobenzoic acid from 3-bromo-5-nitrobenzoic acid was as follows: concentrated hydrochloric acid (30 mL) was slowly added to a solution containing 3-bromo-5-nitrobenzoic acid (7.02 g, 28.54 mmol) and ethanol (150 mL), and the mixture was stirred for 5 min at room temperature. Subsequently, tin (II) chloride was added and the reaction mixture was stirred at 50 °C for 2 hours. After completion of the reaction, the mixture was cooled to room temperature. The pH was adjusted to 9 with 8 M sodium hydroxide solution, at which point a solid precipitated. The solids were removed by filtration. The filtrate was acidified to pH 5 with hydrochloric acid and the target product 3-amino-5-bromobenzoic acid was precipitated, which was filtered to give 5.8 g (94% yield). The product was analyzed by HPLC/MS with a retention time of 4.67 min, LRMS: m/z 216 (M-1).

References

[1] Patent: EP2196465, 2010, A1. Location in patent: Page/Page column 42; 43
[2] Patent: EP2394998, 2011, A1. Location in patent: Page/Page column 22-23
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 23, p. 10479 - 10497
[4] Justus Liebigs Annalen der Chemie, 1884, vol. 222, p. 169
[5] Organic and Biomolecular Chemistry, 2005, vol. 3, # 20, p. 3757 - 3766

3-AMINO-5-BROMOBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-AMINO-5-BROMOBENZOIC ACID manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 3-AMINO-5-BROMOBENZOIC ACID 42237-85-4
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-24

Henan Fengda Chemical Co., Ltd

Product: 3-AMINO-5-BROMOBENZOIC ACID 42237-85-4
Price: US $3.00-0.20/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-26

Career Henan Chemical Co

Product: 3-Amino-5-bromobenzoic acid 42237-85-4
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-25

42237-85-4, 3-AMINO-5-BROMOBENZOIC ACIDRelated Search:

3-Bromo-5-nitrobenzoic acid 3-AMINO-5-BROMOBENZOIC ACID 3-ACETAMIDO-5-BROMOBENZOIC ACID 5-BROMO-2-NITRO-3-ACETYL-AMINO-4-METHYLBENZOIC ACID 3-BROMO-2-NITRO-5-AMINOBENZOIC ACID 2-NITRO-3-AMINO-4-METHYL-5-BROMOBENZOIC ACID RARECHEM AL BE 0950 3-BROMO-4-METHYL-5-NITROBENZOIC ACID 5-(ACETYLAMINO)-3-BROMO-2-NITRO-BENZOIC ACID 3-BROMO-4-METHYL-5-NITROBENZOIC ACID METHYL ESTER 5-BROMO-2-METHYL-3-NITROBENZOIC ACID RARECHEM AL BI 0950 RARECHEM AL BO 2199 RARECHEM AL BF 0950 3-BROMO-2,6-DIMETHOXY-5-NITROBENZOIC ACID RARECHEM AL BO 0536 DINITRO BROMO FLUORESCEIN RARECHEM AL BI 0746

Benzoicacid,3-aMino-5-broMo-

3-Amino-6-bromobenzoic acid

3-AMINO-5-BROMOBENZOIC ACID USP/EP/BP

42237-85-4

Peptide Chemistry

Unnatural Amino Acid Derivatives

Aromatic Amino Acids

Building Blocks

Carbonyl Compounds

Carboxylic Acids

Chemical Biology

Chemical Synthesis

Organic Building Blocks

Aromatic Amino AcidsCarbonyl Compounds

Carboxylic Acids

Peptide Synthesis

Unnatural Amino Acid Derivatives