5-BROMO-2-METHYL-3-NITROBENZOIC ACID

Product Name: 5-BROMO-2-METHYL-3-NITROBENZOIC ACID
CAS No.: 107650-20-4
Chemical Name: 5-BROMO-2-METHYL-3-NITROBENZOIC ACID
Synonyms: AKOS BB-9545;-3-nitrobenzoic acid;5-Bromo-2-methyl-3-nitrobenzoicAci;5-BROMO-2-METHYL-3-NITROBENZOIC ACID;Benzoic acid, 5-broMo-2-Methyl-3-nitro-;5-BROMO-2-METHYL-3-NITROBENZOIC ACID ISO 9001：2015 REACH
CBNumber: CB8460277
Molecular Formula: C8H6BrNO4
Formula Weight: 260.04
MOL File: 107650-20-4.mol

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5-BROMO-2-METHYL-3-NITROBENZOIC ACID Property

Boiling point:: 377.0±42.0 °C(Predicted)
Density: 1.777±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 2?+-.0.20(Predicted)
InChI: InChI=1S/C8H6BrNO4/c1-4-6(8(11)12)2-5(9)3-7(4)10(13)14/h2-3H,1H3,(H,11,12)
InChIKey: DXUUJILVHXQDCV-UHFFFAOYSA-N
SMILES: C1(C(C)=C(C(=O)O)C=C(Br)C=1)[N+]([O-])=O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B687510
Product name: 5-Bromo-2-methyl-3-nitrobenzoicAcid
Packaging: 10g
Price: $130
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0105115
Product name: 5-BROMO-2-METHYL-3-NITROBENZOIC ACID
Purity: 95.00%
Packaging: 1G
Price: $145.95
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB32995
Product name: 5-Bromo-2-methyl-3-nitrobenzoic acid
Packaging: 5G
Price: $150
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0105115
Product name: 5-BROMO-2-METHYL-3-NITROBENZOIC ACID
Purity: 95.00%
Packaging: 10G
Price: $1589.28
Updated: 2021/12/16

AK Scientific

Product number: X8853
Product name: 5-Bromo-2-methyl-3-nitrobenzoicacid
Packaging: 1g
Price: $20
Updated: 2021/12/16

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5-BROMO-2-METHYL-3-NITROBENZOIC ACID Chemical Properties,Usage,Production

Uses

5-Bromo-2-methyl-3-nitrobenzoic Acid is a reactant in the preparation of EPZ005687 (E592200), a potent and selective inhibitor of EZH2.

Synthesis

1975-50-4

107650-20-4

General procedure for the synthesis of 2-methyl-3-nitro-5-bromobenzoic acid from 2-methyl-3-nitrobenzoic acid: N-bromosuccinimide (15 g, 84.3 mmol) was added to a concentrated sulfuric acid solution (60 mL) containing 2-methyl-3-nitrobenzoic acid (15 g, 82.8 mmol). The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the reaction solution was slowly poured into ice water (400 mL). The precipitate was collected by filtration and dried under vacuum to give 21 g of the target product 2-methyl-3-nitro-5-bromobenzoic acid in 98% yield.

References

[1] Patent: US2012/264734, 2012, A1. Location in patent: Page/Page column 100
[2] Patent: WO2012/142513, 2012, A1. Location in patent: Page/Page column 288
[3] Patent: US2014/107122, 2014, A1. Location in patent: Paragraph 0157; 0158
[4] Patent: WO2003/99275, 2003, A1. Location in patent: Page 101
[5] Patent: US2007/219212, 2007, A1. Location in patent: Page/Page column 23

5-BROMO-2-METHYL-3-NITROBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-METHYL-3-NITROBENZOIC ACID Suppliers

China 145 Germany 2 India 8 United Kingdom 2 United States 7 Global 164

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View Lastest Price from 5-BROMO-2-METHYL-3-NITROBENZOIC ACID manufacturers

Henan Fengda Chemical Co., Ltd

Product: 5-Bromo-2-methyl-3-nitrobenzoic acid 107650-20-4
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-13

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-2-METHYL-3-NITROBENZOIC ACID 107650-20-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-2-METHYL-3-NITROBENZOIC ACID 107650-20-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

107650-20-4, 5-BROMO-2-METHYL-3-NITROBENZOIC ACIDRelated Search:

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AKOS BB-9545

5-BROMO-2-METHYL-3-NITROBENZOIC ACID

-3-nitrobenzoic acid

5-Bromo-2-methyl-3-nitrobenzoicAci

5-BROMO-2-METHYL-3-NITROBENZOIC ACID ISO 9001：2015 REACH

107650-20-4