3-Bromo-5-nitrobenzoic acid
- Product Name
- 3-Bromo-5-nitrobenzoic acid
- CAS No.
- 6307-83-1
- Chemical Name
- 3-Bromo-5-nitrobenzoic acid
- Synonyms
- 3-BR-5-NO2-BENZOIC ACID;3-Bromo-5-nitrobenzoic aci;3-BROMO-5-NITROBENZOIC ACID;3-Brom-5-nitro-benzoic acid;3-Bromo-5-carboxynitrobenzene;3-Bromo-5-nitrobenzoicAcid>Benzoic acid, 3-bromo-5-nitro-;3-Bromo-5-nitrobenzoic acid, 99%,;3-Bromo-5-nitrobenzoic acid ISO 9001：2015 REACH
- CBNumber
- CB3331675
- Molecular Formula
- C7H4BrNO4
- Formula Weight
- 246.01
- MOL File
- 6307-83-1.mol
3-Bromo-5-nitrobenzoic acid Property
- Melting point:
- 159-161°C
- Boiling point:
- 376.8±32.0 °C(Predicted)
- Density
- 1.892±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 3.09±0.10(Predicted)
- color
- White to Light yellow to Light orange
- BRN
- 2051365
- InChIKey
- AXRKIZCFYZBBPX-UHFFFAOYSA-N
- CAS DataBase Reference
- 6307-83-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,N,Xn
- Risk Statements
- 36/37/38-50-22
- Safety Statements
- 26-36/37/39-61-60-36/37-37
- HazardClass
- IRRITANT
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B3370
- Product name
- 3-Bromo-5-nitrobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $37
- Updated
- 2025/07/31
- Product number
- B3370
- Product name
- 3-Bromo-5-nitrobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $147
- Updated
- 2025/07/31
- Product number
- B697955
- Product name
- 3-Bromo-5-nitrobenzoic Acid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B697955
- Product name
- 3-Bromo-5-nitrobenzoic Acid
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- OR5735
- Product name
- 3-Bromo-5-nitrobenzoic Acid
- Purity
- 95%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
3-Bromo-5-nitrobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
white to slightly yellow crystalline needles
Synthesis Reference(s)
The Journal of Organic Chemistry, 72, p. 5867, 2007 DOI: 10.1021/jo070477u
Synthesis
121-92-6
6307-83-1
Part G: Preparation of 3-bromo-5-nitrobenzoic acid 3-Nitrobenzoic acid (16.7 g, 100 mmol) was dissolved in a mixed solution of trifluoroacetic acid (50 mL) and sulfuric acid (20 mL) at 50 °C. Subsequently, N-bromosuccinimide (26.7 g, 150 mmol) was added in three batches over 3 hours. The reaction mixture was stirred at 50 °C for 16 h and then cooled to room temperature. The reaction mixture was slowly poured into ice water (200 mL) and extracted three times with ethyl acetate. The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was recrystallized by dichloromethane to give the white solid product 3-bromo-5-nitrobenzoic acid (17.7 g, 72% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 13.8 (broad peak, 1H, carboxylic acid proton), 8.60 (single peak, 1H, aromatic proton), 8.55 (single peak, 1H, aromatic proton), 8.37 (single peak, 1H, aromatic proton).
References
[1] ChemMedChem, 2014, vol. 9, # 5, p. 973 - 983
[2] Journal of the American Chemical Society, 2017, vol. 139, # 36, p. 12579 - 12590
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 4, p. 1556 - 1564
[4] Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5867 - 5869
[5] Chemistry - A European Journal, 2011, vol. 17, # 10, p. 2987 - 2995
3-Bromo-5-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Bromo-5-nitrobenzoic acid manufacturers
- Product
- 3-Bromo-5-nitrobenzoic acid 6307-83-1
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-24
- Product
- 3-Bromo-5-nitrobenzoic acid 6307-83-1
- Price
- US $20.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-10-16
- Product
- 3-Bromo-5-nitrobenzoic acid 6307-83-1
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25