2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER
- Product Name
- 2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER
- CAS No.
- 70146-78-0
- Chemical Name
- 2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER
- Synonyms
- Diethyl-(4-brombenzyl)malonat;diethyl 2-(4-broMobenzyl)Malonate;2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER;diethyl 2-[(4-bromophenyl)methyl]propanedioate;1,3-diethyl 2-[(4-bromophenyl)methyl]propanedioate;Propanedioic acid, 2-[(4-bromophenyl)methyl]-, 1,3-diethyl ester
- CBNumber
- CB51009775
- Molecular Formula
- C14H17BrO4
- Formula Weight
- 329.19
- MOL File
- 70146-78-0.mol
2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER Property
- Boiling point:
- 193-198 °C(Press: 14 Torr)
- Density
- 1.344±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 12.35±0.59(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- HCH0117068
- Product name
- 2-(4-BROMO-BENZYL)MALONIC ACID DIETHYL ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.58
- Updated
- 2021/12/16
- Product number
- CM254636
- Product name
- Diethyl2-(4-bromobenzyl)malonate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $982
- Updated
- 2021/12/16
- Product number
- CD12041442
- Product name
- Diethyl2-(4-bromobenzyl)malonate
- Purity
- 97%
- Packaging
- 5g
- Price
- $1040
- Updated
- 2021/12/16
- Product number
- 70146780
- Product name
- Diethyl2-(4-bromobenzyl)malonate
- Packaging
- 5g
- Price
- $1261.75
- Updated
- 2021/12/16
- Product number
- CM254636
- Product name
- Diethyl2-(4-bromobenzyl)malonate
- Purity
- 95+%
- Packaging
- 10g
- Price
- $1636
- Updated
- 2021/12/16
2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER Chemical Properties,Usage,Production
Synthesis
589-15-1
105-53-3
70146-78-0
Sodium metal (5.82 g, 0.25 mol) was added to ethanol (240 mL) and stirred until the sodium was completely dissolved. 1-Bromo-4-bromomethylbenzene (37.35 g, 0.15 mol) and diethyl malonate (78 g, 0.49 mol) were then added. The reaction mixture was slowly heated to reflux overnight. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in distilled water and extracted with ether. The organic layer was washed sequentially with 0.5 N aqueous hydrochloric acid and saturated brine, dried over anhydrous sodium sulfate and concentrated to give diethyl 2-(4-bromobenzyl)malonate (40 g, 85% yield).
References
[1] Patent: WO2010/105179, 2010, A2. Location in patent: Page/Page column 76
[2] Journal of Organic Chemistry, 1984, vol. 49, # 22, p. 4226 - 4237
[3] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1994, vol. 30, # 8, p. 905 - 915
[4] Khimiya Geterotsiklicheskikh Soedinenii, 1993, # 8, p. 1052 - 1062
[5] Tetrahedron Asymmetry, 2001, vol. 12, # 4, p. 585 - 596
2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER manufacturers
- Product
- 2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER 70146-78-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-10