5-Fluoro-2-Methoxybenzyl alcohol
- Product Name
- 5-Fluoro-2-Methoxybenzyl alcohol
- CAS No.
- 426831-32-5
- Chemical Name
- 5-Fluoro-2-Methoxybenzyl alcohol
- Synonyms
- (5-Fluoro-2-methoxyphenyl);5-Fluoro-3-methoxybenzyl alcohol;5-FLUORO-2-METHOXYBENZYL ALCOHOL;Benzenemethanol, 5-fluoro-2-methoxy-;Benzenemethanol, 5-fluoro-2-methoxy- (9CI)
- CBNumber
- CB51065694
- Molecular Formula
- C8H9FO2
- Formula Weight
- 156.15
- MOL File
- 426831-32-5.mol
5-Fluoro-2-Methoxybenzyl alcohol Property
- Boiling point:
- 242℃
- Density
- 1.187
- Flash point:
- 119℃
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.09±0.10(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C8H9FO2/c1-11-8-3-2-7(9)4-6(8)5-10/h2-4,10H,5H2,1H3
- InChIKey
- NJDNHGOIOZXFCB-UHFFFAOYSA-N
- SMILES
- C1(CO)=CC(F)=CC=C1OC
Safety
- HS Code
- 2909498090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F597470
- Product name
- 5-Fluoro-2-methoxybenzyl alcohol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 2607-3-52
- Product name
- 5-Fluoro-2-methoxybenzyl alcohol
- Packaging
- 5G
- Price
- $61
- Updated
- 2021/12/16
- Product number
- 117225
- Product name
- 5-Fluoro-2-methoxybenzyl alcohol
- Packaging
- 1g
- Price
- $93
- Updated
- 2021/12/16
- Product number
- PC7735
- Product name
- 5-Fluoro-2-methoxybenzyl alcohol
- Packaging
- 1g
- Price
- $12
- Updated
- 2021/12/16
- Product number
- 2607-3-52
- Product name
- 5-Fluoro-2-methoxybenzyl alcohol
- Packaging
- 1g
- Price
- $20
- Updated
- 2021/12/16
5-Fluoro-2-Methoxybenzyl alcohol Chemical Properties,Usage,Production
Synthesis
19415-51-1
426831-32-5
To a methanolic solution of 5-fluoro-2-methoxybenzaldehyde (11.093 g, 1 eq., purchased from Aldrich Chemical Company) was added sodium borohydride (7.515 g, 2.7 eq.) in batches at -10 °C and under nitrogen protection. The reaction solution was slowly warmed to room temperature and stirred for 30 minutes before the methanol solvent was removed by reduced pressure distillation and replaced with dichloromethane. The reaction mixture was poured into ice water and extracted with dichloromethane. The organic phases were combined, dried with magnesium sulfate and concentrated under reduced pressure to remove the solvent to give 5-fluoro-2-methoxybenzyl alcohol as a colorless oil (9.794 g, 87% yield).1H NMR (300 MHz, CDCl3) δ: 2.58 (m, 1H), 3.81 (s, 3H), 4.63 (d, 2H, J=6.3 Hz), 6.78 (dd, 1H J=8.9 and 4.3 Hz), 6.94 (td, 1H, J=8.5 and 3.1 Hz), 7.04 (dd, 1H, J=8.7 and 3.1 Hz).
References
[1] Patent: EP1216225, 2005, B1. Location in patent: Page/Page column 39
[2] Patent: WO2004/18441, 2004, A1. Location in patent: Page 22
[3] Patent: WO2005/20975, 2005, A2. Location in patent: Page/Page column 126
[4] Patent: WO2005/20976, 2005, A2. Location in patent: Page/Page column 129
[5] Patent: WO2005/60949, 2005, A2. Location in patent: Page/Page column 132; 277
5-Fluoro-2-Methoxybenzyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Fluoro-2-Methoxybenzyl alcohol manufacturers
- Product
- Benzenemethanol, 5-fluoro-2-methoxy- (9CI) 426831-32-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- Benzenemethanol, 5-fluoro-2-methoxy- (9CI) 426831-32-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- Benzenemethanol, 5-fluoro-2-methoxy- (9CI) 426831-32-5
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02