Lodoxamidetromethamine
- Product Name
- Lodoxamidetromethamine
- CAS No.
- 63610-09-3
- Chemical Name
- Lodoxamidetromethamine
- Synonyms
- AloMide;AlMide;U-42585-E;LodoxaMide troMetaMol;Lodoxamidetromethamine;Lodoxamide Tromethamide;LodoxaMide troMethaMineon;LodoxaMide troMethaMine salt;Lodoxamide tromethamine (U 42585 E);2-Amino-2-(hydroxymethyl)propane-1,3-diol hemi(2,2'-((2-chloro-5-cyano-1,3-phenylene)bis(azanediyl))bis(2-oxoacetate))
- CBNumber
- CB51074423
- Molecular Formula
- C15H17ClN4O9
- Formula Weight
- 432.77
- MOL File
- 63610-09-3.mol
Lodoxamidetromethamine Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- DMSO: 20 mg/mL (36.11 mM and warming)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-6465
- Product name
- Lodoxamide(tromethamine)
- Purity
- 99.37%
- Packaging
- 100mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- CS-6465
- Product name
- Lodoxamide(tromethamine)
- Purity
- 99.37%
- Packaging
- 5mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CS-6465
- Product name
- Lodoxamide(tromethamine)
- Purity
- 99.37%
- Packaging
- 10mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 9710AB
- Product name
- Lodoxamidetromethamine
- Packaging
- 1mg
- Price
- $73
- Updated
- 2021/12/16
- Product number
- 9710AB
- Product name
- Lodoxamidetromethamine
- Packaging
- 5mg
- Price
- $87
- Updated
- 2021/12/16
Lodoxamidetromethamine Chemical Properties,Usage,Production
Description
Lodoxamide tromethamine was launched as an ophthalmic formulation for the treatment of allergic conjunctivitis. It appears to act as a mast cell stabilizer inhibiting degranulation and the release of histamine and other vasoactive products in a similar manner to sodium cromoglycate. The compound is also under investigation as an orally active antiallergic/antiasthmatic agent.
Originator
Upjohn (U.S.A.)
Uses
cataract treatment
brand name
Alomide (Alcon);Almide.
General Description
Lodoxamidetromethamine, N, N -(2-chloro-5-cyano-m-phenylene)dioxamicacid (Alomide), is a white crystalline, water-solublepowder. The only significant structural similarity betweenlodoxamide and cromolyn and nedocromil is the presence oftwo acidic groups. Lodoxamide is indicated in the treatmentof the ocular disorders including vernal keratoconjunctivitis,vernal conjunctivitis, and vernal keratitis. Lodoxamide isavailable as a 0.1% solution, with each milliliter containing1.78 mg of lodoxamide tromethamine equivalent to 1 mg oflodoxamide. The solution contains the preservative benzalkoniumchloride (0.007%) as well as mannitol, hydroxypropylmethylcellulose, sodium citrate, citric acid, edetatedisodium, tyloxapol, hydrochloric acid and/or sodium hydroxide(to adjust pH), and purified water.
The dose for adults and children older than 2 years of ageis 1 to 2 drops in each affected eye 4 times daily for up to 3months. The most frequently reported ocular adverse experienceswere transient burning, stinging, or discomfort oninstillation.
Lodoxamidetromethamine Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from Lodoxamidetromethamine manufacturers
- Product
- Lodoxamidetromethamine 63610-09-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26
- Product
- Lodoxamidetromethamine 63610-09-3
- Price
- US $1.00/Kg/Drum
- Min. Order
- 25Kg/Drum
- Purity
- 99.00%
- Supply Ability
- 1ton
- Release date
- 2019-10-29
- Product
- Lodoxamidetromethamine 63610-09-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500kg
- Release date
- 2018-08-19