ChemicalBook > CAS DataBase List > 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

Product Name
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
CAS No.
93107-30-3
Chemical Name
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Synonyms
1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;14002-6N;7-difluoro-4-oxo-1;Valine Impurity 125;Ciprofloxacin Intermediate;CIPROFLOXACIN CARBOXYLIC ACID;Moxifloxacin Difluoro Acid Impurity;Bexifloxacin hydrochloride intermediate *;1-CYCLOPROPYL-6,7-DIFLUORO-4-OXOQUINOLINE-3-CARBOXYLIC ACID;1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carb...
CBNumber
CB51092814
Molecular Formula
C13H9F2NO3
Formula Weight
265.21
MOL File
93107-30-3.mol
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1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Property

Melting point:
289°C(lit.)
Boiling point:
434.2±45.0 °C(Predicted)
Density 
1.630±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO
form 
Solid
pka
6.36±0.41(Predicted)
color 
Off-White
InChI
InChI=1S/C13H9F2NO3/c14-9-3-7-11(4-10(9)15)16(6-1-2-6)5-8(12(7)17)13(18)19/h3-6H,1-2H2,(H,18,19)
InChIKey
KNEXGVPHPGXAGF-UHFFFAOYSA-N
SMILES
N1(C2CC2)C2=C(C=C(F)C(F)=C2)C(=O)C(C(O)=O)=C1
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Safety

Hazard Codes 
Xn
Risk Statements 
62-52/53
Safety Statements 
22-36/37-61
HS Code 
2933.49.7000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L133051
Product name
1-CYCLOPROPYL-6,7-DIFLUORO-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID
Purity
AldrichCPR
Packaging
25MG
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
C2779
Product name
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$74
Updated
2024/03/01
TCI Chemical
Product number
C2779
Product name
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$250
Updated
2021/12/16
TRC
Product number
C989685
Product name
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Packaging
1g
Price
$95
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC33263
Product name
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
Packaging
2g
Price
$60
Updated
2021/12/16
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1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Chemical Properties,Usage,Production

Uses

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid is a metabolite of Moxifloxacin (M745000) and is used in the synthesis of chiral aminopiperidinyl quinolones as potent antibacterial agents against resistant pathogens.

General Description

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid and 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3 -Carboxylic Acid has a similar structure; the difference lies in the number of substituted fluorine atoms. They could be formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Preparation Products And Raw materials

Raw materials

Sodium hydride 2-Chloro-4,5-difluorobenzoic acid Cyclopropylamine Hexane Acetonitrile Nitrogen Ethanol Acetic anhydride N,N-Dimethylformamide Triethyl orthoformate Toluene Carbon tetrachloride 1,4-Dioxane Diethyl ether Acetic acid Methanol Oxalyl chloride Diethyl malonate Magnesium Sulfuric acid

Preparation Products

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1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Suppliers

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View Lastest Price from 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid manufacturers

Shaanxi Franta Biotechnology Co., Ltd
Product
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid 93107-30-3
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-09-23
Career Henan Chemical Co
Product
1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID 93107-30-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-30

93107-30-3, 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic AcidRelated Search:

Perfluoro-1-iodohexane METHYL 1-N-CYCLOPROPYL-6,7-DIFLUORO-8-METHYL-5-NITRO-4-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLATE 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester 1-CYCLOPROPYL-6,7-DIFLUORO-8-DIFLUOROMETHOXY-4-OXO-3-QUINOLINE CARBOXYLIC ACID ETHYL 1-CYCLOPROPYL-5,6,7,8-TETRAFLUORO-4(1H)-OXOQUINOLINE-3-CARBOXYLATE 1-CYCLOPROPYL-5-NITRO-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3- QUINOLINECARBOXYLIC ACID ETHYL ESTER 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid AKOS 1130 5-AMINO-1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-8-METHYL-4-OXO-3-QUINOLINECARBOCYLIC ACID 1-CYCLOPROPYL-5-AMIDO-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3- QUINOLINECARBOXYLIC ACID ETHYL ESTER ethyl 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydroquinoline-4-oxo-3-carboxyla 1-CYCLOPROPYL-6,7-DIFLUORO-5-METHYL-4-OXO-3-QUINOLINE CARBOXYLIC ACID 1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoq 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

  • 1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 6,7-DIFLUORO-4-OXO-1-CYCLOPROPYL-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID
  • 1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 1-CYCLOPROPYL-6,7-DIFLUORO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6,7- difluoro-1,4-dihydro-4-oxo-
  • Ciprofloxacin Intermediate
  • Moxifloxacin Difluoro Acid Impurity
  • 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid &gt
  • CIPROFLOXACIN CARBOXYLIC ACID
  • 7-difluoro-4-oxo-1
  • 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carb...
  • Bexifloxacin hydrochloride intermediate *
  • CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 14002-6N
  • 1-Cyclorpropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinoline Carboxylic Acid
  • Valine Impurity 125
  • 93107-30-3