4-(CHLOROSULFONYL)BENZOIC ACID
- Product Name
- 4-(CHLOROSULFONYL)BENZOIC ACID
- CAS No.
- 10130-89-9
- Chemical Name
- 4-(CHLOROSULFONYL)BENZOIC ACID
- Synonyms
- AKOS BB-9471;ClSO2C6H4COOH;RARECHEM AL BO 0540;4-(CHLOROSULFONYL)BE;OTAVA-BB BB7020430958;4-(Chlorsulfonyl)benzoesure;(Chlorosulfonyl)benzoic Acid;4-(chlorosulfonyl)-benzoicaci;P-(CHLOROSULFONYL)BENZOIC ACID;4-(CHLOROSULFONYL)BENZOIC ACID
- CBNumber
- CB5109294
- Molecular Formula
- C7H5ClO4S
- Formula Weight
- 220.63
- MOL File
- 10130-89-9.mol
4-(CHLOROSULFONYL)BENZOIC ACID Property
- Melting point:
- 230 °C
- Boiling point:
- 379.1±25.0 °C(Predicted)
- Density
- 1.5116 (estimate)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in DMSO, Methanol
- pka
- 3.09±0.10(Predicted)
- form
- Powder
- color
- Off-white to beige
- Water Solubility
- Reacts with water.
- Sensitive
- Moisture Sensitive
- CAS DataBase Reference
- 10130-89-9(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 4-(chlorosulfonyl)- (10130-89-9)
Safety
- Hazard Codes
- C
- Risk Statements
- 34-29-22
- Safety Statements
- 8-45-36/37/39-26
- RIDADR
- 3261
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29173990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- 252700
- Product name
- 4-(Chlorosulfonyl)benzoic acid
- Purity
- 96%
- Packaging
- 1g
- Price
- $35.62
- Updated
- 2025/07/31
- Product number
- 252700
- Product name
- 4-(Chlorosulfonyl)benzoic acid
- Purity
- 96%
- Packaging
- 5g
- Price
- $47.88
- Updated
- 2025/07/31
- Product number
- 252700
- Product name
- 4-(Chlorosulfonyl)benzoic acid
- Purity
- 96%
- Packaging
- 25g
- Price
- $104.3
- Updated
- 2025/07/31
- Product number
- C383100
- Product name
- (Chlorosulfonyl)benzoicAcid
- Packaging
- 2.5g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- J96715
- Product name
- 4-(Chlorosulfonyl)benzoic acid
- Packaging
- 10g
- Price
- $75
- Updated
- 2021/12/16
4-(CHLOROSULFONYL)BENZOIC ACID Chemical Properties,Usage,Production
Chemical Properties
off-white to beige powder
Uses
4-(Chlorosulfonyl)benzoic acid was used in the preparation of polymer bound transfer hydrogenation catalyst and 4-(carboxymethyl-sulfamoyl)-benzoyladenosine. It was also used as a reagent in the sulfonation of γ-cyclodextrin.
Synthesis
104-15-4
10130-89-9
The general procedure for the synthesis of 4-(chlorosulfonyl)benzoic acid from 4-methylphenylsulfonic acid was as follows: a solution of potassium permanganate (KMnO4, 1.6 g) in water (H2O, 13 mL) was added slowly and dropwise at 80 °C to a solution of 4-methylphenylsulfonic acid (1.7 g, 10 mmol) and potassium hydroxide (KOH, 0.68 g, 12 mmol) in water (H2O, a 15 mL) solution. Upon completion of the reaction, the mixture was poured into ethanol (EtOH, 20 mL), filtered and concentrated to give potassium 4-carboxybenzenesulfonate (1.2 g). This intermediate was used directly in the next reaction without further purification. At room temperature, chlorosulfonic acid (4 mL) was slowly added dropwise to a stirring solution of potassium 4-carboxybenzenesulfonate (1.2 g). The reaction mixture was continued to be stirred for 2 hours and then poured into crushed ice. The resulting solid product was collected by filtration and washed with water (H2O) to give 4-(chlorosulfonyl)benzoic acid (0.22 g) as a white solid in 20% yield. The melting point of the product was 230-232 °C (literature value: 228-232 °C); 1H-NMR (CDCl3, 400 MHz) data: δ 8.30 (d, J=8.0 Hz, 2H), 8.42 (d, J=8.0 Hz, 2H).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 2, p. 958 - 962
4-(CHLOROSULFONYL)BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(CHLOROSULFONYL)BENZOIC ACID manufacturers
- Product
- 4-(Chlorosulfonyl)benzoic acid 10130-89-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-19
- Product
- 4-(CHLOROSULFONYL)BENZOIC ACID 10130-89-9
- Price
- US $85.00-850.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-11-13
- Product
- 4-(Chlorosulfonyl)Benzoic Acid 10130-89-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09