3-(Chlorosulfonyl)benzoic acid
- Product Name
- 3-(Chlorosulfonyl)benzoic acid
- CAS No.
- 4025-64-3
- Chemical Name
- 3-(Chlorosulfonyl)benzoic acid
- Synonyms
- AKOS BB-9469;AKOS BBS-00006994;RARECHEM AL BO 0793;TIMTEC-BB SBB003351;3-(Chlorosulfonyl)be;3-Chlorosulfony benzoic acid;3-(chlorosulfonyl)-benzoicaci;3-(CHLOROSULFONYL)BENZOIC ACID;3-(CHLOROSULPHONYL)BENZOIC ACID;M-(CHLOROSULFONYL) BENZOIC ACID
- CBNumber
- CB1476213
- Molecular Formula
- C7H5ClO4S
- Formula Weight
- 220.63
- MOL File
- 4025-64-3.mol
3-(Chlorosulfonyl)benzoic acid Property
- Melting point:
- 128-130 °C(lit.)
- Boiling point:
- 402.5±28.0 °C(Predicted)
- Density
- 1.591±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 3.00±0.10(Predicted)
- color
- White to Brown
- Sensitive
- Moisture Sensitive
- BRN
- 2645465
- CAS DataBase Reference
- 4025-64-3(CAS DataBase Reference)
- NIST Chemistry Reference
- M-(chlorosulfonyl)benzoic acid(4025-64-3)
- EPA Substance Registry System
- Benzoic acid, 3-(chlorosulfonyl)- (4025-64-3)
Safety
- Hazard Codes
- C
- Risk Statements
- 34-29-22
- Safety Statements
- 26-27-36/37/39-45
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- 441759
- Product name
- 3-(Chlorosulfonyl)benzoic acid
- Purity
- 95%
- Packaging
- 5g
- Price
- $25.8
- Updated
- 2025/07/31
- Product number
- 441759
- Product name
- 3-(Chlorosulfonyl)benzoic acid
- Purity
- 95%
- Packaging
- 25g
- Price
- $86.1
- Updated
- 2025/07/31
- Product number
- C3466
- Product name
- 3-(Chlorosulfonyl)benzoic Acid
- Packaging
- 5G
- Price
- $28
- Updated
- 2025/07/31
- Product number
- C3466
- Product name
- 3-(Chlorosulfonyl)benzoic Acid
- Packaging
- 25G
- Price
- $112
- Updated
- 2025/07/31
- Product number
- C384970
- Product name
- 3-(Chlorosulfonyl)benzoic Acid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
3-(Chlorosulfonyl)benzoic acid Chemical Properties,Usage,Production
Chemical Properties
white to light beige crystalline powder
General Description
3-(Chlorosulfonyl)benzoic acid is a sulfonyl halide. It participates in the synthesis of novel anthranilic acid class of PPARδ (Peroxisome proliferator-activated receptor δ) partial agonists.
Synthesis
65-85-0
4025-64-3
1.22 g (10 mmol) of benzoic acid was accurately weighed into a 50 mL pear shaped flask and 10 mL of chlorosulfonic acid was slowly added. The reaction mixture was stirred at 100°C for 45 minutes. Upon completion of the reaction, the reaction solution was slowly added dropwise to ice brine followed by vacuum filtration. The resulting solid was washed with cold water and finally dried under vacuum to obtain 3-chlorosulfonylbenzoic acid in white solid form in 88.7% yield.
References
[1] Patent: CN105732444, 2016, A. Location in patent: Paragraph 0031; 0032; 0036; 0037; 0038
[2] Patent: WO2014/100833, 2014, A1. Location in patent: Paragraph 0076
[3] Journal of Heterocyclic Chemistry, 1982, vol. 19, p. 961 - 965
[4] Patent: US2005/49307, 2005, A1. Location in patent: Page/Page column 5
[5] European Journal of Medicinal Chemistry, 2014, vol. 89, p. 503 - 523
3-(Chlorosulfonyl)benzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(Chlorosulfonyl)benzoic acid manufacturers
- Product
- 3-(Chlorosulfonyl)benzoic acid 4025-64-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-19
- Product
- 3-(Chlorosulfonyl)benzoic acid 4025-64-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 97%
- Supply Ability
- 1000kg
- Release date
- 2018-12-18