ChemicalBook > CAS DataBase List > 3-(Chlorosulfonyl)benzoic acid

3-(Chlorosulfonyl)benzoic acid

Product Name
3-(Chlorosulfonyl)benzoic acid
CAS No.
4025-64-3
Chemical Name
3-(Chlorosulfonyl)benzoic acid
Synonyms
AKOS BB-9469;AKOS BBS-00006994;RARECHEM AL BO 0793;TIMTEC-BB SBB003351;3-(Chlorosulfonyl)be;3-Chlorosulfony benzoic acid;3-(chlorosulfonyl)-benzoicaci;3-(CHLOROSULFONYL)BENZOIC ACID;3-(CHLOROSULPHONYL)BENZOIC ACID;M-(CHLOROSULFONYL) BENZOIC ACID
CBNumber
CB1476213
Molecular Formula
C7H5ClO4S
Formula Weight
220.63
MOL File
4025-64-3.mol
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3-(Chlorosulfonyl)benzoic acid Property

Melting point:
128-130 °C(lit.)
Boiling point:
402.5±28.0 °C(Predicted)
Density 
1.591±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
3.00±0.10(Predicted)
color 
White to Brown
Sensitive 
Moisture Sensitive
BRN 
2645465
CAS DataBase Reference
4025-64-3(CAS DataBase Reference)
NIST Chemistry Reference
M-(chlorosulfonyl)benzoic acid(4025-64-3)
EPA Substance Registry System
Benzoic acid, 3-(chlorosulfonyl)- (4025-64-3)
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Safety

Hazard Codes 
C
Risk Statements 
34-29-22
Safety Statements 
26-27-36/37/39-45
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
441759
Product name
3-(Chlorosulfonyl)benzoic acid
Purity
95%
Packaging
5g
Price
$25.8
Updated
2025/07/31
Sigma-Aldrich
Product number
441759
Product name
3-(Chlorosulfonyl)benzoic acid
Purity
95%
Packaging
25g
Price
$86.1
Updated
2025/07/31
TCI Chemical
Product number
C3466
Product name
3-(Chlorosulfonyl)benzoic Acid
Packaging
5G
Price
$28
Updated
2025/07/31
TCI Chemical
Product number
C3466
Product name
3-(Chlorosulfonyl)benzoic Acid
Packaging
25G
Price
$112
Updated
2025/07/31
TRC
Product number
C384970
Product name
3-(Chlorosulfonyl)benzoic Acid
Packaging
250mg
Price
$55
Updated
2021/12/16
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3-(Chlorosulfonyl)benzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to light beige crystalline powder

General Description

3-(Chlorosulfonyl)benzoic acid is a sulfonyl halide. It participates in the synthesis of novel anthranilic acid class of PPARδ (Peroxisome proliferator-activated receptor δ) partial agonists.

Synthesis

65-85-0

4025-64-3

1.22 g (10 mmol) of benzoic acid was accurately weighed into a 50 mL pear shaped flask and 10 mL of chlorosulfonic acid was slowly added. The reaction mixture was stirred at 100°C for 45 minutes. Upon completion of the reaction, the reaction solution was slowly added dropwise to ice brine followed by vacuum filtration. The resulting solid was washed with cold water and finally dried under vacuum to obtain 3-chlorosulfonylbenzoic acid in white solid form in 88.7% yield.

References

[1] Patent: CN105732444, 2016, A. Location in patent: Paragraph 0031; 0032; 0036; 0037; 0038
[2] Patent: WO2014/100833, 2014, A1. Location in patent: Paragraph 0076
[3] Journal of Heterocyclic Chemistry, 1982, vol. 19, p. 961 - 965
[4] Patent: US2005/49307, 2005, A1. Location in patent: Page/Page column 5
[5] European Journal of Medicinal Chemistry, 2014, vol. 89, p. 503 - 523

3-(Chlorosulfonyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-(Chlorosulfonyl)benzoic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3-(Chlorosulfonyl)benzoic acid 4025-64-3
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-19
Career Henan Chemical Co
Product
3-(Chlorosulfonyl)benzoic acid 4025-64-3
Price
US $1.00/kg
Min. Order
1kg
Purity
97%
Supply Ability
1000kg
Release date
2018-12-18

4025-64-3, 3-(Chlorosulfonyl)benzoic acidRelated Search:

4-Aminobenzoic acid Benzoic acid Ethyl 2-(Chlorosulfonyl)acetate 3-Nitrobenzoic acid Estradiol benzoate Folic acid 3-Hydroxybenzoic acid 4-Nitrobenzoic acid 3-Aminobenzoic acid 4-(Chloromethyl)benzoic acid m-Toluic acid Chlorosulfonyl isocyanate 3-Chloroperoxybenzoic acid Citric acid Ascoric Acid 2-Methoxy-5-(chlorosulfonyl)benzoic acid 4-CHLORO-3-CHLOROSULFONYLBENZOIC ACID 2-Hydroxy-5-(chlorosulfonyl)benzoic acid

  • 3-CARBOXYPHENYLSULFONYLCHLORIDE
  • 3-CARBOXY-BENZENESULFONYL CHLORIDE
  • 3-(CHLOROSULPHONYL)BENZOIC ACID
  • 3-(CHLOROSULFONYL)BENZOIC ACID
  • AKOS BBS-00006994
  • AKOS BB-9469
  • M-(CHLOROSULFONYL) BENZOIC ACID
  • BENZOIC ACID, 3-(CHLOROSULFONYL)-
  • TIMTEC-BB SBB003351
  • RARECHEM AL BO 0793
  • 3-(chlorosulfonyl)-benzoicaci
  • 2-[(3-methoxyphenyl)thio]acetic acid
  • 3-Carboxylbenzenesulfonylchloride
  • Benzoic acid, m-(chlorosulfonyl)-
  • 3-(Chlorosulfonyl)Benzoic Acid UN 3261
  • 3-(Chlorosulfonyl)benzoic acid ,97%
  • 3-Chlorosulfony benzoic acid
  • 3-(CHLOROSULFONYL)BENZOIC ACID, 98+%
  • 3-Carboxybenzenesulphonyl chloride
  • 3-(Chlorosulfonyl)be
  • 4025-64-3
  • C7H5ClO4S
  • C7H5O4ClS
  • ClSO2C6H4CO2H
  • SULFONYL CHLORIDE
  • Organic Building Blocks
  • Sulfur Compounds
  • Sulfonyl Halides
  • Building Blocks
  • Fluorobenzene
  • Benzene derivates
  • Organic Building Blocks
  • Sulfonyl Halides
  • Sulfur Compounds
  • bc0001